Effects of exercise and muscle type on BDNF, NT-4/5, and TrKB expression in skeletal muscle

Muscle and Nerve

Volumn 41, Issue 3, 2010, Pages 385-391

  Ogborn, Daniel I ^a,b   Gardiner, Phillip F ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Brain derived neurotrophic factor; Gene expression; Neurotrophin 4 5; Skeletal muscle; Treadmill exercise; Tropomyosin related kinase B

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA; NEUROTROPHIN 4;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXERCISE; FEMALE; GASTROCNEMIUS MUSCLE; GENE EXPRESSION; GENE EXPRESSION REGULATION; NEUROMUSCULAR FUNCTION; NEUROMUSCULAR SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SKELETAL MUSCLE; SOLEUS MUSCLE; SPRAGUE DAWLEY RAT; TREADMILL; TREADMILL EXERCISE;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; FEMALE; MUSCLE, SKELETAL; NERVE GROWTH FACTORS; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 77649106224     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.21503     Document Type: Article

References (33)

1. Funakoshi H, Belluardo N, Arenas E, Yamamoto Y, Casabona A, Persson H, et al. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science 1995;268:1495-1499.
2. Griesbeck O, Parsadanian AS, Sendtner M, Thoenen H. Expression of neurotrophins in skeletal muscle: quantitative comparison and significance for motoneuron survival and maintenance of function. J Neurosci Res 1995;42:21-33.
3. Mousavi K, Jasmin BJ. BDNF is expressed in skeletal muscle satellite cells and inhibits myogenic differentiation. J Neurosci 2006;26: 5739-5749.
4. Beaumont E, Gardiner PF. Endurance training alters the biophysical properties of hindlimb motoneurons in rats. Muscle Nerve 2003;27: 228-236.
5. Munson JB, Foehring RC, Mendell LM, Gordon T. Fast-to-slow conversion following chronic low-frequency activation of medial gastrocnemius muscle in cats. II. Motoneuron properties. J Neurophysiol 1997;77:2605-2615.
6. Carrasco DI, English AW. Neurotrophin 4/5 is required for the normal development of the slow muscle fiber phenotype in the rat soleus. J Exp Biol 2003;206:2191-2200.
7. Gonzalez M, Collins WF III.Modulation of motoneuron excitability by brain-derived neurotrophic factor. J Neurophysiol 1997;77: 502-506.
8. Adlard PA, Perreau VM, Engesser-Cesar C, Cotman CW. The time-course of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise. Neurosci Lett 2004;363:43-48.
9. Gomez-Pinilla F, Ying Z, Roy RR, Molteni R, Edgerton VR. Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. J Neurophysiol 2002;88:2187-2195.
10. Cuppini R, Sartini S, Agostini D, Guescini M, Ambrogini P, Betti M, et al. BDNF expression in rat skeletal muscle after acute or repeated exercise. Arch Ital Biol 2007;145:99-110.
11. Gomez-Pinilla F, Ying Z, Opazo P, Roy RR, Edgerton VR. Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle. Eur J Neurosci 2001;13:1078-1084.
12. Neeper SA, Gomez-Pinilla F, Choi J, Cotman C. Exercise and brain neurotrophins. Nature 1995;373:109.
13. Oliff HS, Berchtold NC, Isackson P, Cotman CW. Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Brain Res Mol Brain Res 1998;61:147-153.
14. Klein R, Lamballe F, Bryant S, Barbacid M. The trkB tyrosine protein kinase is a receptor for neurotrophin-4. Neuron 1992;8:947-956.
15. Klein R, Nanduri V, Jing SA, Lamballe F, Tapley P, Bryant S, et al. The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 1991;66:395-403.
16. Walker UA, Schon EA. Neurotrophin-4 is up-regulated in ragged-red fibers associated with pathogenic mitochondrial DNA mutations. Ann Neurol 1998;43:536-540.
17. Funakoshi H, Frisen J, Barbany G, Timmusk T, Zachrisson O, Verge VM, et al. Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. J Cell Biol 1993; 123:455-465.
18. Sakuma K, Watanabe K, Sano M, Uramoto I, Nakano H, Li YJ, et al. A possible role for BDNF, NT-4 and TrkB in the spinal cord and muscle of rat subjected to mechanical overload, bupivacaine injection and axotomy. Brain Res 2001;907:1-19.
19. Zhao S, Fernald RD. Comprehensive algorithm for quantitative realtime polymerase chain reaction. J Comput Biol 2005;12:1047-1064.
20. Mahoney DJ, Carey K, Fu MH, Snow R, Cameron-Smith D, Parise G, et al. Real-time RT-PCR analysis of housekeeping genes in human skeletal muscle following acute exercise. Physiol Genomics 2004;18: 226-231.
21. Widenfalk J, Olson L, Thoren P. Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain. Neurosci Res 1999;34:125-132.
22. Jeneson JA, de Snoo MW, Verlinden NA, Joosten BJ, Doornenbal A, Schot A, et al. Treadmill but not wheel running improves fatigue resistance of isolated extensor digitorum longus muscle in mice. Acta Physiol (Oxf) 2007;190:151-161.
23. Gardiner KR, Gardiner PF, Edgerton VR. Guinea pig soleus and gastrocnemius electromyograms at varying speeds, grades, and loads. J Appl Physiol 1982;52:451-457.
24. Zhang S, Zettler C, Cupler EJ, Hurtado P, Wong K, Rush RA. Neurotrophin 4/5 immunoassay: identification of sources of errors for the quantification of neurotrophins. J Neurosci Methods 2000;99: 119-127.
25. Mitsui T, Kawai H, Nagasawa M, Kunishige M, Akaike M, Kimura Y, et al. Oxidative damage to skeletal muscle DNA from patients with mitochondrial encephalomyopathies. J Neurol Sci 1996;139:111-116.
26. Gomez-Cabrera MC, Borras C, Pallardo FV, Sastre J, Ji LL, Vina J. Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats. J Physiol 2005;567: 113-120.
27. Kim MW, Bang MS, Han TR, Ko YJ, Yoon BW, Kim JH, et al. Exercise increased BDNF and trkB in the contralateral hemisphere of the ischemic rat brain. Brain Res 2005;1052:16-21.
28. Vaynman S, Ying Z, Gomez-Pinilla F. Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience 2003;122:647-657.
29. Vaynman S, Ying Z, Gomez-Pinilla F. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur J Neurosci 2004;20:2580-2590.
30. Wiedemann FR, Siemen D, Mawrin C, Horn TF, Dietzmann K. The neurotrophin receptor TrkB is colocalized to mitochondrial membranes. Int J Biochem Cell Biol 2006;38:610-620.
31. Delp MD, Duan C. Composition and size of type I, IIA, IID/X, and IIB fibers and citrate synthase activity of rat muscle. J Appl Physiol 1996;80:261-270.
32. Roy RR, Baldwin KM, Martin TP, Chimarusti SP, Edgerton VR. Biochemical and physiological changes in overloaded rat fast- and slow-twitch ankle extensors. J Appl Physiol 1985;59:639-646.
33. Middlemas DS, Lindberg RA, Hunter T. trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. Mol Cell Biol 1991;11:143-153.