Oxidative damage to skeletal muscle DNA from patients with mitochondrial encephalomyopathies

Journal of the Neurological Sciences

Volumn 139, Issue 1, 1996, Pages 111-116

  Mitsui, Takao ^a   Kawai, Hisaomi ^a   Nagasawa, Masakazu ^b   Kunishige, Makoto ^a   Akaike, Masashi ^a   Kimura, Yuzo ^b   Saito, Shiro ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

8 Hydroxy deoxyguanosine; Encephalomyopathy; Oxygen radical; Skeletal muscle; Superoxide dismutase

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; FREE RADICAL; SUPEROXIDE DISMUTASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOPATHY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION; MUSCLE BIOPSY; PRIORITY JOURNAL;

EID: 0030200795     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-510X(96)00043-3     Document Type: Article

References (36)

1. Akaike, M., H. Kawai, S. Kashiwagi, M. Kunishige and S. Saito, (1995) A case of Kearns-Sayre syndrome whose asymptomatic mother had abnormal mitochondria in skeletal muscle (in Japanese). Clin. Neurol., 35: 190-194.
2. Bessho, T., K. Tano, H. Kasai and S. Nishimura (1992) Deficiency of 8-hydroxyguanine DNA endonuclease activity and accumulation of the 8-hydroxyguanine in mutator mutant (MutM) of Escherichia Coli. Biochem. Biophys. Res. Commun., 188: 372-378.
3. Bessho, T., K. Tano, H. Kasai, E. Ohtsuka and S. Nishimura (1993) Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in human cells. J. Biol. Chem., 268: 19416-19421.
4. Boveris, A. and B. Chance (1973) The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J., 134: 707-716.
5. Brown, W.M., M. George and A.C. Wilson (1979) Rapid evolution of animal mitochondrial DNA. Proc. Natl. Acad. Sci. USA, 76: 1967-1971.
6. Chance, B., H. Sies and A. Boveris (1979) Hydroperoxide metabolism in mammalian organs. Phys. Rev., 59: 527-605.
7. Chappell, J.B. and S.V. Perry (1954) Biochemical and osmotic properties of skeletal muscle mitochondria. Nature, 173: 1094-1095.
8. Cheng, K.C., D.S. Cahill, H. Kasai, S. Nishimura and L.A. Loeb (1992) 8-Hydroxyguanosine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions. J. Biol. Chem., 267: 166-172.
9. Clayton, D.A. (1982) Replication of animal mitochondrial DNA. Cell, 28: 693-705.
10. Cox, B.C. (1976) Bacterial mutator genes and the control of spontaneous mutation. Annu. Rev. Genet., 10: 135-156.
11. DiMauro, S. and C.T. Moraes (1993) Mitochondrial encephalomy-opathies. Arch. Neurol., 50: 1197-1208.
12. Engel, A.C., M. Yamamoto and K.H. Fischbeck (1994) Dystrophinopathies. In: A.G. Engel and C. Franzini-Armstrong (Eds.), Myology, 2nd edn., McGraw-Hill, New York, pp. 1130-1187.
13. Fiala, E.S., C.C. Conaway and J.E. Mathis (1989) Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res., 49: 5518-5522.
14. Floyd, R.A. and J.M. Carney (1992) Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann. Neurol., 32: S22-S27.
15. Fridovich, I. (1989) Superoxide dismutases. An adaptation to a paramagnetic gas. J. Biol. Chem., 264: 7761-7764.
16. Hayakawa, M., K. Torii, S. Sugiyama, M. Tanaka and T. Ozawa (1991a) Age-associated accumulation of 8-hyroxydeoxyguanosine in mitochondrial DNA of human diaphragm. Biochem. Biophys. Res. Commun., 179: 1023-1029.
17. Hayakawa, M., T. Ogawa, S. Sugiyama, M. Tanaka and T. Ozawa (1991b) Massive conversion of guanosine to 8-hydroxy-guanosine in mouse liver mitochondrial DNA by administration of azidothymidine. Biochem. Biophys. Res. Commun., 176: 87-93.
18. Kominami, E., K. Ii and N. Katunuma (1987) Activation of intramyofibral autophagic lysosomal system in muscular dystrophy. Am. J. Pathol., 127: 461-466.
19. Kuchino, Y., F. Mori, H. Kasai, H. Inoue, S. Iwai, K. Miura, E. Ohtsuka and S. Nishimura (1987) Misreading of DNA templates containing 8-hydroxyoxyguanosine at the modified base and adjacent residues. Nature, 327: 77-79.
20. Larsson, N.G., B. Holme, B. Kristiansson, A. Oldfords and M. Tulinius (1990) Progressive increase of the mutated mitochondrial DNA fraction in Kearns-Sayre syndrome. Pediatr. Res., 28: 131-136.
21. Linnane, A.W., S. Marzuki, T. Ozawa and M. Tanaka (1989) Mitochondrial DNA mutations as an important contributor to aging and degenerative diseases. Lancet, 25: 642-645.
22. Michaels, M.L., C. Cruz, A.P. Grollman and J.M. Miller (1992) Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA. Proc. Natl. Acad. Sci. USA, 89: 7022-7025.
23. Miquel, J. (1992) An update on the mitochondrial-DNA mutation hypothesis of cell aging. Mutation Res., 275: 209-216.
24. Mitsui, T., H. Kawai, T. Naruo, H. Nishino and S. Saito (1993) In situ hybridization of myoglobin mRNA: results on the skeletal muscles of normal subjects and patients with neuromuscular diseases. Acta Neuropathol., 86: 313-318.
25. Morgan-Hughes, J.A. (1992) Mitochondrial diseases. In: F.L. Mastaglia and J.N. Walton (Eds.), Skeletal Muscle Pathology, 2nd edn., Churchill Livingstone, London, pp. 367-424.
26. Muramatsu, M., Y. Hayashi, T. Onishi, M. Sakai, K. Takai and T. Kashiyama (1974) Rapid isolation of nucleoli from detargent purified nuclei of various tumor and tissue culture cells. Exp. Cell Res., 88: 345-351.
27. Ozawa, T., M. Tanaka, S. Sugiyama, K. Hattori, T. Ito, K. Ohno, A. Takahashi, W. Sato, G. Takada, B. Mayumi, K. Yamamoto, K. Adachi, Y. Koga and H. Toshima (1990) Multiple mitochondrial DNA deletions exist in cardiomyocytes of patients with hypertrophic or dilated cardiomyopathy. Biochem. Biophys. Res. Commun., 170: 830-836.
28. Pearson, C.M. and N.C. Kar (1979) Muscle breakdown and lysosomal activation (Biochemistry). Ann. New York Acad Sci., 317: 465-477.
29. Piccolo, G., P. Banfi, G. Azan, R. Rizzuto, R. Bisson, D. Sadoná and G. Bellomo (1991) Biological markers of oxidative stress in mitochondrial myopathies with progressive external ophthalmoplegia. J. Neurol. Sci., 105: 57-60.
30. Reeardon, W., R.J.M. Ross, M.G. Sweeney, L.M. Luxon, M.E. Pembrey, A.E. Harding and R.C. Trembath (1992) Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA. Lancet, 340: 1376-1379.
31. Richter, C. (1988) Do mitochondrial DNA fragments promote cancer and aging? FEBS Lett., 241: 1-5.
32. Richter, C. (1992) Reactive oxygen and DNA damage in mitochondria. Mutation Res., 275: 249-255.
33. Richter, C., J.-W. Park and B.N. Ames (1988) Normal oxdative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA, 85: 6465-6467.
34. Shibutani, S., M. Takeshita and A.P. Grollman (1991) Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature, 349: 431-434.
35. Tritshler, H.-J. and R. Medori (1993) Mitochondrial DNA alterations as a source of human disorders. Neurology, 43: 280-288.
36. Yanofsky, C., E.G. Cox and V. Horn (1966) The unusual mutagenic specificity of an E. coli mutator gene. Proc. Natl. Acad. Sci. USA, 55: 274-281.