Upregulation of neurodevelopmental genes during scarless healing

Annals of Plastic Surgery

Volumn 64, Issue 2, 2010, Pages 247-250

  Antony, Anuja K ^a   Kong, Wuyi ^b   Lorenz, H Peter ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Neurodevelopmental genes; Neurotrophic; Peripheral nerve; Scarless healing

Indexed keywords

CYTOKINE; MEMBRANE PROTEIN; NERVE GROWTH FACTOR; NEUROPEPTIDE;

ANGIOGENESIS; ANIMAL; ARTICLE; FETUS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; RAT; SIGNAL TRANSDUCTION; SKIN; SPRAGUE DAWLEY RAT; UPREGULATION; WOUND HEALING;

ANIMALS; CYTOKINES; FETUS; MEMBRANE GLYCOPROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEUROPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SKIN; UP-REGULATION; WOUND HEALING;

EID: 77649092840     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/SAP.0b013e3181a20af8     Document Type: Article

References (42)

1. Colwell AS, Longaker MT, Lorenz HP. Mammalian fetal organ regeneration. Adv Biochem Eng Biotechnol. 2005;93:83-100.
2. Soo C, Beanes SR, Hu FY, et al. Ontogenetic transition in fetal wound transforming growth factor-beta regulation correlates with collagen organization. Am J Pathol. 2003;163:2459-2476.
3. Colwell AS, Longaker MT, Lorenz HP. Fetal wound healing. Front Biosci. 2003;8:s1240-s1248.
4. Colwell AS, Beanes SR, Soo C, et al. Increased angiogenesis and expression of vascular endothelial growth factor during scarless repair. Plast Reconstr Surg. 2005;115:204-212.
5. Stelnicki EJ, Doolabh V, Lee S, et al. Nerve dependency in scarless fetal wound healing. Plast Reconstr Surg. 2000;105:140-147.
6. Kishi K, Ohyama K, Satoh H, et al. Mutual dependence of murine fetal cutaneous regeneration and peripheral nerve regeneration. Wound Repair Regen. 2006;14:91-99.
7. Altun V, Hakvoort TE, van Zuijlen PP, et al. Nerve outgrowth and neuropeptide expression during the remodeling of human burn wound scars. A 7-month follow-up study of 22 patients. Burns. 2001;27:717-722.
8. Constantinou J, Reynolds ML, Woolf CJ, et al. Nerve growth factor levels in developing rat skin: upregulation following skin wounding. Neuroreport. 1994;5:2281-2284.
9. Kong W, Li S, Longaker MT, et al. Blood-derived small Dot cells reduce scar in wound healing. Exp Cell Res. 2008;314:1529-1539.
10. Beanes SR, Hu FY, Soo C, et al. Confocal microscopic analysis of scarless repair in the fetal rat: defining the transition. Plast Reconstr Surg. 2002;109: 160-170.
11. Piotrowski W, Devoy MA, Jordan CC, et al. The substance P receptor on rat mast cells and in human skin. Agents Actions. 1984;14:420-424.
12. Hosoi J, Murphy GF, Egan CL, et al. Regulation of Langerhans cell function by nerves containing calcitonin gene-related peptide. Nature. 1993;363:159-163.
13. Ansel JC, Kaynard AH, Armstrong CA, et al. Skin-nervous system interactions. J Invest Dermatol. 1996;106:198-204.
14. Olerud JE, Usui ML, Seckin D, et al. Neutral endopeptidase expression and distribution in human skin and wounds. J Invest Dermatol. 1999;112: 873-881.
15. Otsuka M, Yoshioka K. Neurotransmitter functions of mammalian tachykinins. Physiol Rev. 1993;73:229-308.
16. Engin C. Effects of calcitonin gene-related peptide on wound contraction in denervated and normal rat skin: a preliminary report. Plast Reconstr Surg. 1998;101:1887-1890.
17. Scholzen T, Armstrong CA, Bunnett NW, et al. Neuropeptides in the skin: interactions between the neuroendocrine and the skin immune systems. Exp Dermatol. 1998;7:81-96.
18. Nakamura M, Nishida T, Ofuji K, et al. Synergistic effect of substance P with epidermal growth factor on epithelial migration in rabbit cornea. Exp Eye Res. 1997;65:321-329.
19. Haegerstrand A, Dalsgaard CJ, Jonzon B, et al. Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA. 1990;87:3299-3303.
20. Wiedermann CJ, Auer B, Sitte B, et al. Induction of endothelial cell differentiation into capillary-like structures by substance P. Eur J Pharmacol. 1996;298:335-338.
21. Nilsson J, von Euler AM, Dalsgaard CJ. Stimulation of connective tissue cell growth by substance P and substance K. Nature. 1985;315:61-63.
22. Burbach GJ, Kim KH, Zivony AS, et al. The neurosensory tachykinins substance P and neurokinin A directly induce keratinocyte nerve growth factor. J Invest Dermatol. 2001;117:1075-1082.
23. Naik-Mathuria B, Gay AN, Hsu JE, et al. Fetal wound healing using a genetically modified murine model: the contribution of P-selectin. J Pediatr Surg. 2008;43:675-682.
24. Naik-Mathuria B, Gay A, Zhu X, et al. Age-dependent recruitment of neutrophils by fetal endothelial cells: implications in scarless wound healing. J Pediatr Surg. 2007;42:166-171.
25. Levi A, Eldridge JD, Paterson BM. Molecular cloning of a gene sequence regulated by nerve growth factor. Science. 1985;229:393-395.
26. Possenti R, Eldridge JD, Paterson BM, et al. A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway. EMBO J. 1989;8:2217-2223.
27. Salton SR, Fischberg DJ, Dong KW. Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells. Mol Cell Biol. 1991;11:2335-2349.
28. Wilkinson DI, Theeuwes MJ, Farber EM. Nerve growth factor increases the mitogenicity of certain growth factors for cultured human keratinocytes: a comparison with epidermal growth factor. Exp Dermatol. 1994;3:239-245.
29. Ghosh A, Ginty DD, Bading H, et al. Calcium regulation of gene expression in neuronal cells. J Neurobiol. 1994;25:294-303.
30. de Groot RP, Karperien M, Pals C, et al. Characterization of the mouse junD promoter- high basal level activity due to an octamer motif. EMBO J. 1991;10:2523-2532.
31. Thiel G, Schoch S, Petersohn D. Regulation of synapsin I gene expression by the zinc finger transcription factor zif268/egr-1. J Biol Chem. 1994;269: 15294-15301.
32. Petersohn D, Schoch S, Brinkmann DR, et al. The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2. J Biol Chem. 1995;270:24361-24369.
33. Nef S, Fiumelli H, de Castro E, et al. Identification of neuronal calcium sensor (NCS-1) possibly involved in the regulation of receptor phosphorylation. J Recept Signal Transduct Res. 1995;15:365-378.
34. Kuno T, Kajimoto Y, Hashimoto T, et al. cDNA cloning of a neural visinin-like Ca(2+)-binding protein. Biochem Biophys Res Commun. 1992; 184:1219-1225.
35. Wernersson J, Johansson I, Larsson U, et al. Activated transcription of the human neuropeptide Y gene in differentiating SH-SY5Y neuroblastoma cells is dependent on transcription factors AP-1, AP-2alpha, and NGFI. J Neurochem. 1998;70:1887-1897.
36. Koff A, Polyak KP. 27kip1, an inhibitor of cyclin-dependent kinases. Prog Cell Cycle Res. 1995;1:141-147.
37. Kerkhoff E, Rapp UR. High-intensity Raf signals convert mitotic cell cycling into cellular growth. Cancer Res. 1998;58:1636-1640.
38. Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999;13:1501-1512.
39. Dey A, Li W. Cell cycle-independent induction of D1 and D2 cyclin expression, but not cyclin-Cdk complex formation or Rb phosphorylation, by IFNgamma in macrophages. Biochim Biophys Acta. 2000;1497:135-147.
40. Takuwa N, Takuwa Y. Regulation of cell cycle molecules by the Ras effector system. Mol Cell Endocrinol. 2001;177:25-33.
41. Lukaszewicz A, Savatier P, Cortay V, et al. Contrasting effects of basic fibroblast growth factor and neurotrophin 3 on cell cycle kinetics of mouse cortical stem cells. J Neurosci. 2002;22:6610-6622.
42. Dang CM, Beanes SR, Soo C, et al. Decreased expression of fibroblast and keratinocyte growth factor isoforms and receptors during scarless repair. Plast Reconstr Surg. 2003;111:1969-1979.