Cell culture-induced aberrant methylation of the imprinted IG DMR in human lymphoblastoid cell lines

Epigenetics

Volumn 5, Issue 1, 2010, Pages 50-60

  Saferali, Aabida ^a   Grundberg, Elin ^a   Berlivet, Soizik ^a   Beauchemin, Hugues ^a   Morcos, Lisanne ^a   Polychronakos, Constantin ^a,b   Pastinen, Tomi ^a   Graham, Jinko ^c   McNeney, Brad ^c   Naumova, Anna K ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Cell culture; Chromosome 14q32; DNA methylation; Fibroblasts; Genomic imprinting; IG DMR; Lymphoblastoid cell lines; Osteoblasts

Indexed keywords

POTASSIUM CHANNEL KCNQ1; RNA H19; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN POLYPEPTIDE N; SPACER DNA; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BLOOD CELL; CELL CULTURE; CELL IMMORTALIZATION; CELL LINE; CELL TYPE; CHROMOSOME 14Q; CHROMOSOME ABERRATION; CLONAL VARIATION; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; PROTEIN DOMAIN;

EID: 77449100153     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.5.1.10436     Document Type: Article

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