FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release

Cancer Immunology, Immunotherapy

Volumn 59, Issue 4, 2010, Pages 575-586

  Rolin, Johannes ^a   Sand, Kristin L ^a   Knudsen, Eirunn ^a   Maghazachi, Azzam A ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Dendritic cells; FTY720; Natural killer cells; SEW2871; Sphingosine 1 phosphate; Tumor cells

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; B7 ANTIGEN; CD158 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CYTOKINE; FINGOLIMOD; GAMMA INTERFERON; HLA E ANTIGEN; HLA I ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; LYMPHOCYTE ANTIGEN; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1BETA; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3; NATURAL KILLER CELL RECEPTOR NKG2D; SPHINGOSINE 1 PHOSPHATE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOKINE; DRUG DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; LYSOPHOSPHOLIPID; OXADIAZOLE DERIVATIVE; PROPANEDIOL DERIVATIVE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; THIOPHENE DERIVATIVE;

ANTIGEN EXPRESSION; ARTICLE; CELL INTERACTION; CELL PROTECTION; CELL STIMULATION; CELL STRAIN K 562; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DRUG EFFICACY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MYELOID LEUKEMIA; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL DESTRUCTION; CYTOTOXICITY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; IMMUNOLOGY; METABOLISM; NATURAL KILLER CELL; UPREGULATION;

CHEMOKINES; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; IMMUNOSUPPRESSIVE AGENTS; K562 CELLS; KILLER CELLS, NATURAL; LYSOPHOSPHOLIPIDS; OXADIAZOLES; PROPYLENE GLYCOLS; SPHINGOSINE; THIOPHENES; UP-REGULATION;

EID: 77449097944     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-009-0775-7     Document Type: Article

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