A novel tumor cell line cloned from mutated human embryonic bone marrow mesenchymal stem cells

Oncology Reports

Volumn 12, Issue 3, 2004, Pages 501-508

  Xu, Wenrong ^a,b   Qian, Hui ^a   Zhu, Wei ^a   Chen, Yongchang ^a   Shao, Qixiang ^a   Sun, Xiaochun ^a   Hu, Jiabo ^a   Han, Chongxu ^b   Zhang, Xiran ^b  

^a JIANGSU UNIVERSITY   (China)

^b NANJING NORMAL UNIVERSITY   (China)

Author keywords

Mesenchymal stem cells; Nucleostemin; Tumor cell

Indexed keywords

ANTIGEN; CARRIER PROTEIN; DNA; NUCLEAR PROTEIN; NUCLEOSTEMIN PROTEIN, HUMAN;

ANIMAL; ARTICLE; BIOSYNTHESIS; BONE MARROW; BONE MARROW CELL; CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL MEMBRANE; CELL STRAIN U937; CHEMISTRY; CYTOLOGY; DNA SEQUENCE; ELECTRON MICROSCOPY; FEMALE; FLOW CYTOMETRY; GENETICS; HUMAN; KARYOTYPING; MALE; MESODERM; METABOLISM; MONONUCLEAR CELL; MOUSE; MOUSE MUTANT; MUTATION; NUDE MOUSE; POLYMERASE CHAIN REACTION; PRENATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; TIME; TUMOR CELL LINE;

ANIMALS; ANTIGENS; BONE MARROW; BONE MARROW CELLS; CARRIER PROTEINS; CELL LINE, TUMOR; CELL MEMBRANE; CELLS, CULTURED; DNA; FEMALE; FLOW CYTOMETRY; G0 PHASE; G1 PHASE; HUMANS; KARYOTYPING; LEUKOCYTES, MONONUCLEAR; MALE; MESODERM; MICE; MICE, NUDE; MICE, SCID; MICROSCOPY, ELECTRON; MUTATION; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; S PHASE; SEQUENCE ANALYSIS, DNA; STEM CELLS; TIME FACTORS; U937 CELLS;

EID: 7744245892     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.12.3.501     Document Type: Article

References (32)

1. Clark AD, Jorgensen HG, Mountford J and Holyoake TL: Isolation and therapeutic potential of human haemopoietic stem cells. Cytotechnology 41: 111-131, 2003. (Pubitemid 37045951)
2. Deviene SM, Lazarus HM and Emerson SG: Clinical application of hematopoietic progenitor cell expansion: current status and future prospects. Bone Marrow Transplant 31: 241-252, 2003. (Pubitemid 36336226)
3. Eglitis MA and Mezey E: Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice. Proc Natl Acad Sci USA 94: 4080-4085, 1997. (Pubitemid 27180502)
4. Ferrari G, Cusella-De Angelis G, Goletta M, Paolucci E, Stornaiuolo A, Cossu G and Mavilio F: Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279: 1528-1530, 1998. (Pubitemid 28217075)
5. Jackson KA, Majka SM, Wan H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK and Goodell MA: Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 107: 1395-1402, 2001. (Pubitemid 32522033)
6. Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N, Boggs SS, Greenberger JS and Goff JP: Bone marrow as a potential source of hepatic oval cells. Science 284: 1168-1170, 1999. (Pubitemid 29288406)
7. Theise ND, Badve S, Saxena R, Henegariu O, Seil S, Crawford JM and Krause DS: Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 31: 235-240, 2000. (Pubitemid 30033713)
8. Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G, Teperman L, Henegariu O and Krause DS: Liver from bone marrow in humans. Hepatology 32: 11-16, 2000. (Pubitemid 30432360)
9. Spees JL, Olson SD, Ylostalo J, Lynch PJ, Smith J, Perry A, Peister A, Wang MY and Prockop DJ: Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma. Proc Natl Acad Sci USA 100: 2397-2402, 2003. (Pubitemid 36297510)
10. Preston SL, Alison MR, Forbes SJ, Direkze NC, Poulsom R and Wright NA: The new stem cell biology: something for everyone. J Clin Pathol Mol Pathol 56: 86-96, 2003. (Pubitemid 36461469)
11. Mckay R: A more astonishing hypothesis. Nat Biotl 20: 426- 427, 2002.
12. Stocum DL: Development. A tail of transdifferentiation. Science 298: 1901-1903, 2002.
13. Liu Y and Rao MS: Transdifferentiation - fact or artifact. J Cell Biochem 88: 29-40, 2003. (Pubitemid 36015072)
14. Holden C: Stem cell research. Cells find destiny though merger. Science 300: 35, 2003.
15. Orlic D, Hill JM and Arai AE: Stem cells for myocardial regeneration. Circ Res 91: 1092-1102, 2002. (Pubitemid 36076357)
16. Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Olson S and Grompe M: Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature 422: 897-901, 2003. (Pubitemid 36520042)
17. Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, Nakano Y, Meyer EM, Morel L, Peterson BE and Scott EW: Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416: 542-545, 2002. (Pubitemid 34288856)
18. Ying QL, Nichols J, Evans EP and Smith AG: Changing potency by spontaneous fusion. Nature 416: 545-547, 2002.
19. Marx J: Mutant stem cells may seed cancer. Science 301: 1308-1310, 2003.
20. Tu SM, Lin SH and Logothetis CJ: Stem-cell origin of metastasis and heterogeneity in solid tumours. Lancet Oncol 3: 508-513, 2002.
21. Smalley M and Ashworth A: Stem cells and breast cancer: A field in transit. Nature 3: 832-843, 2003.
22. Dick JE: Breast cancer stem cells revealed. Proc Natl Acad Sci USA 100: 3547-3549, 2003.
23. Reya T, Morrison S J, Clarke MF and Weissman IL: Stem cells, cancer, and cancer stem cells. Nature 414: 105-111, 2001. (Pubitemid 33041634)
24. Xu WR, Zhang XR and Qian H: Basic biologic characteristics, separation and purification of human mesenchymal stem cells derived from adult bone marrow. Chin J Clin Lab Sci 21: 193-195, 2003.
25. Sun XC, Xu WR and Yao K: Induction of the differetiation of fetal bone marrow mesenchymal stem cells into neural cells in vitro. Chin J Bio Eng 23: 1-4, 2004.
26. Rangappa S, Reddy VG, Bongso A, Lee EH and Sim EKW: Transformation of the adult human mesenchymal stem cells into cardiomyocyte-like cells in vivo. Cardiovasc Engineering 2: 7-14, 2002.
27. Pittenger ME Mackay AM, Beck SC, Jasiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Graig S and Marshak DR: Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147, 1999. (Pubitemid 29282067)
28. Nagler A, Korenstein-Ilan A, Amiel A and Avivi L: Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells. Exp Hematol 32: 122-130, 2004. (Pubitemid 38064408)
29. Tsai RY and Mckay RD: A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev 16: 2991-3003, 2002. (Pubitemid 35424188)
30. Michael D and Oren M: The p53 and Mdm2 families in cancer. Curr Opin Genet Dev 12: 53-59, 2002. (Pubitemid 34094990)
31. Bernardi R and Pandolfi PP: The nucleolus: at the stem of immortality. Nat Med 9: 24-25, 2003. (Pubitemid 36098255)
32. Normile D: Cell proliferation: common control for cancer, stem cells. Science 298: 1869-1870, 2002.