Notch pathway is dispensable for adipocyte specification

Genesis (United States)

Volumn 40, Issue 1, 2004, Pages 40-44

  Nichols, Amy M ^a   Pan, Yonghua ^a   Herreman, An ^b   Hadland, Brandon K ^a   De Strooper, Bart ^b   Kopan, Raphael ^a   Huppert, Stacey S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Adipogenesis; Chimera; Notch

Indexed keywords

NOTCH RECEPTOR;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BODY WEIGHT; CELL DIFFERENTIATION; CELL FATE; CELL SPECIFICITY; ENERGY BALANCE; FOOD INTAKE; GENETIC ASSOCIATION; LIPID METABOLISM; LIPID STORAGE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 7744224387     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.20061     Document Type: Article

References (29)

1. Artavanis-Tsakonas S, Rand MD, Lake RJ. 1999. Notch signaling: cell fate control and signal integration in development. Science 284: 770-776.
2. Bellows CG, Wang YH, Heersche JN, Aubin JE. 1994. 1,25-Dihydroxyvitamin D3 stimulates adipocyte differentiation in cultures of fetal rat calvaria cells: comparison with the effects of dexamethasone. Endocrinology 134:2221-2229.
3. Conlon RA, Reaume AG, Rossant J. 1995. Notch1 is required for the coordinate segmentation of somites. Development 121:1533-1545.
4. Dani C. 1999. Embryonic stem cell-derived adipogenesis. Cells Tissues Organs 165:173-180.
5. Dani C, Smith AG, Dessolin S, Leroy P, Staccini L, Villageois P, Darimont C, Ailhaud G. 1997. Differentiation of embryonic stem cells into adipocytes in vitro. J Cell Sci 110:1279-1285.
6. Field SJ, Johnson RS, Mortensen RM, Papaioannou VE, Speigelman BM, Greenberg ME. 1992. Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proc Natl Acad Sci U S A 89:9306-9310.
7. Garces C, Ruiz-Hidalgo MJ, de Mora JF, Park C, Meile L, Goldstein J, Bonvini E, Porras A, Laborda J. 1997. Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis. J Biol Chem 272:29729-29734.
8. Gossler A, Doetschman T, Korn R, Serfling E, Kemler R. 1986. Transgenesis by means of blastocyst-derived embryonic stem cell lines. Proc Natl Acad Sci U S A 83:9065-9069.
9. Gregoire FM, Smas CM, Sul HS. 1998. Understanding adipocyte differentiation. Physiol Rev 78:783-809.
10. Hadland BK, Huppert SS, Kanugo J, Xue Y, Jiang R, Gridley T, Conlon RA, Cheng AM, Kopan R, Longmore GD. 2004. A requirement for Notch1 distinguishes two phases of definitive hematopoiesis during development. Blood; DOI:10.1182/blood-2004-03-1224.
11. Hartmann D, Strooper BD, Serneels L, Craessaerts K, Herreman A, Annaert W, Umans L, Lubke T, Illert AL, Figura KV, Saftig P. 2002. The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for α-secretase activity in fibroblasts. Hum Mol Genet 11:2615-2624.
12. Herreman A, Hartmann D, Annaert W, Saftig P, Craessaerts K, Serneels L, Umans L, Schrijvers V, Checler F, Vanderstichele H, Dressel VBR, Cupers P, Huylebroeck D, Zwijsen A, Leuven FV, Strooper BD. 1999. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal pehnotype of presenilin 1 deficiency. Proc Natl Acad Sci U S A 96:11872-11877.
13. Herreman A, Serneels L, Annaert W, Collen D, Schoonjans L, Strooper BD. 2000. Total inactivation of γ-secretase activity in presenilin-deficient embryonic stem cells. Nat Cell Biol 2:461-462.
14. Hwang C-S, Loftus TM, Mandrup S, Lane MD. 1997. Adipocyte differentiation and leptin expression. Annu Rev Cell Dev Biol 13:231-259.
15. Kato H, Taniguchi Y, Kurooka H, Minoguchi S, Sakai T, Nomura-Okazaki S, Tamura K, Honjo T. 1997. Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development 124:4133-4141.
16. Keller GM. 1995. In vitro differentiation of embryonic stem cells. Curr Opin Cell Biol 7:862-869.
17. MacDougald OA, Mandrup S. 2002. Adipogenesis: forces that tip the scales. Trends Endocrinol Metab 13:5-11.
18. Mizutani T, Taniguchi Y, Aoki T, Hashimoto N, Honjo T. 2001. Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members. Proc Natl Acad Sci U S A 98:9026-9031.
19. Oka C, Nakano T, Wakeham A, Pompa JLdl, Mori C, Sakai T, Okazaki S, Kawaichi M, Shiota K, Mak TW, Honjo T. 1995. Disruption of the mouse RBP-Jk gene results in early embryonic death. Development 121:3291-3301.
20. Pairault J, Lasnier F. 1979. A study of the adipose conversion of suspended 3T3 cells by using glycerophosphate dehydrogenase as differentiation marker. Proc Natl Acad Sci U S A 76:5138-5142.
21. Ross DA, Rao PK, Kadesch T. 2004. Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes. Mol Cell Biol 24:3505-3513.
22. Ruiz-Hidalgo MJ, Garces C, Laborda J. 1999. Notch-1 expression levels in 3T3-L1 cells influence ras signalling and transformation by oncogenic ras. Int J Oncol 14:777-783.
23. Sage J, Miller AL, Perez-Mancera PA. Wysocki JM, Jacks T. 2003. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 424:223-228.
24. Saxena M-DT. 2001. A functional and biochemical comparison of the four murine Notch homologs. In: Division of biology and biomedical sciences. St. Louis: Washington University.
25. Saxena MT, Schroeter EH, Mumm JS, Kopan R. 2001. Murine Notch homologs (N1-4) undergo presenilin-dependent proteolysis. J Biol Chem 276:40268-40273.
26. Schroeder T, Fraser ST, Ogawa M, Nishikawa S, Oka C, Bornkamm GW, Nishikawa S-I, Honjo T, Just U. 2003. Recombination signal sequence-binding protein Jk alters mesodermal cell fate decisions by suppressing cardiomyogenesis. Proc Natl Acad Sci U S A 100: 4018-4023.
27. Sciaudone M, Gazzerro E, Priest L, Delany AM, Canalis E. 2003. Notch 1 impairs osteoblastic cell differentiation. Endocrinology 144:5631-5639.
28. Swiatek PJ, Lindsell CE, Amo FFD, Weinmaster G, Gridley T. 1994. Notch1 is essential for postimplantation development in mice. Genes Dev 8:707-719.
29. Vanderstraeten-Gregoire F. 1989. La Differentiation In Vitro des Precurseurs des Cellules Adipeuses de Rat. Louvain: Universite Catholique de Louvain.