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Volumn 104, Issue 4, 2010, Pages 481-496

Pulmonary vasodilator testing and use of calcium channel blockers in pulmonary arterial hypertension

Author keywords

Epoprostenol; Nitric oxide; Pulmonary artery drug effects; Pulmonary hypertension; Vascular resistance drug effects; Vasodilator agents diagnostic use

Indexed keywords

ADENOSINE; ANOREXIGENIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; ILOPROST; NITRIC OXIDE; PROSTACYCLIN; SILDENAFIL; VASODILATOR AGENT;

EID: 77349113347     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2009.11.015     Document Type: Review
Times cited : (86)

References (111)
  • 1
    • 4143111667 scopus 로고    scopus 로고
    • American College of Chest Physicians. Diagnosis and management of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • Rubin L.J. American College of Chest Physicians. Diagnosis and management of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 7S-10S
    • (2004) Chest , vol.126
    • Rubin, L.J.1
  • 2
    • 2942522878 scopus 로고    scopus 로고
    • Clinical classification of pulmonary hypertension
    • Simonneau G., Galiè N., Rubin L.J., et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol 43 (2004) 5S-12S
    • (2004) J Am Coll Cardiol , vol.43
    • Simonneau, G.1    Galiè, N.2    Rubin, L.J.3
  • 3
    • 67649579669 scopus 로고    scopus 로고
    • Updated clinical classification of pulmonary hypertension
    • Simonneau G., Robbins I.M., Beghetti M., et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 54 (2009) S43-S54
    • (2009) J Am Coll Cardiol , vol.54
    • Simonneau, G.1    Robbins, I.M.2    Beghetti, M.3
  • 4
    • 3142692425 scopus 로고    scopus 로고
    • American College of Chest Physicians. Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • McGoon M., Gutterman D., Steen V., et al. American College of Chest Physicians. Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 14S-34S
    • (2004) Chest , vol.126
    • McGoon, M.1    Gutterman, D.2    Steen, V.3
  • 5
    • 34250870730 scopus 로고    scopus 로고
    • Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines
    • Badesch D.B., Abman S.H., Simonneau G., Rubin L.J., and McLaughlin V.V. Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines. Chest 131 (2007) 1917-1928
    • (2007) Chest , vol.131 , pp. 1917-1928
    • Badesch, D.B.1    Abman, S.H.2    Simonneau, G.3    Rubin, L.J.4    McLaughlin, V.V.5
  • 6
    • 64849109410 scopus 로고    scopus 로고
    • ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association
    • McLaughlin V.V., Archer S.L., Badesch D.B., et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. J Am Coll Cardiol 53 (2009) 1573-1619
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1573-1619
    • McLaughlin, V.V.1    Archer, S.L.2    Badesch, D.B.3
  • 7
    • 67649632034 scopus 로고    scopus 로고
    • Diagnosis and assessment of pulmonary arterial hypertension
    • Badesch D.B., Champion H.C., Sanchez M.A., et al. Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol 54 (2009) S55-S66
    • (2009) J Am Coll Cardiol , vol.54
    • Badesch, D.B.1    Champion, H.C.2    Sanchez, M.A.3
  • 8
    • 10044258461 scopus 로고    scopus 로고
    • Task Force. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology
    • Galiè N., Torbicki A., Barst R., et al. Task Force. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology. Eur Heart J 25 (2004) 2243-2278
    • (2004) Eur Heart J , vol.25 , pp. 2243-2278
    • Galiè, N.1    Torbicki, A.2    Barst, R.3
  • 9
    • 0025837793 scopus 로고
    • Survival in patients with primary pulmonary hypertension. Results from a national prospective registry
    • D'Alonzo G.E., Barst R.J., Ayres S.M., et al. Survival in patients with primary pulmonary hypertension. Results from a national prospective registry. Ann Intern Med 115 (1991) 343-349
    • (1991) Ann Intern Med , vol.115 , pp. 343-349
    • D'Alonzo, G.E.1    Barst, R.J.2    Ayres, S.M.3
  • 10
    • 41949104810 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • Chin K.M., and Rubin L.J. Pulmonary arterial hypertension. J Am Coll Cardiol 51 (2008) 1527-1538
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1527-1538
    • Chin, K.M.1    Rubin, L.J.2
  • 11
    • 0024804879 scopus 로고
    • The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension
    • Weir E.K., Rubin L.J., Ayres S.M., et al. The acute administration of vasodilators in primary pulmonary hypertension. Experience from the National Institutes of Health Registry on Primary Pulmonary Hypertension. Am Rev Respir Dis 140 (1989) 1623-1630
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1623-1630
    • Weir, E.K.1    Rubin, L.J.2    Ayres, S.M.3
  • 12
    • 33845343982 scopus 로고    scopus 로고
    • Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers
    • Hoeper M.M., Lee S.H., Voswinckel R., et al. Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers. J Am Coll Cardiol 48 (2006) 2546-2552
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2546-2552
    • Hoeper, M.M.1    Lee, S.H.2    Voswinckel, R.3
  • 14
    • 0010342978 scopus 로고
    • Correlation of acute prostacyclin response in primary (unexplained) pulmonary hypertension with efficacy of treatment with calcium channel blockers and survival
    • Weir K. (Ed), Plenum Press, New York
    • Groves B.M., Badesch D.B., Turkevich D., et al. Correlation of acute prostacyclin response in primary (unexplained) pulmonary hypertension with efficacy of treatment with calcium channel blockers and survival. In: Weir K. (Ed). In flux in pulmonary vascular control (1993), Plenum Press, New York
    • (1993) In flux in pulmonary vascular control
    • Groves, B.M.1    Badesch, D.B.2    Turkevich, D.3
  • 15
    • 0031869664 scopus 로고    scopus 로고
    • Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension
    • Sitbon O., Humbert M., Jagot J.L., et al. Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. Eur Respir J 12 (1998) 265-270
    • (1998) Eur Respir J , vol.12 , pp. 265-270
    • Sitbon, O.1    Humbert, M.2    Jagot, J.L.3
  • 16
    • 3142726157 scopus 로고    scopus 로고
    • American College of Chest Physicians. Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • Badesch D.B., Abman S.H., Ahearn G.S., et al. American College of Chest Physicians. Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest 126 (2004) 35S-62S
    • (2004) Chest , vol.126
    • Badesch, D.B.1    Abman, S.H.2    Ahearn, G.S.3
  • 17
    • 0026632785 scopus 로고
    • The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
    • Rich S., Kaufmann E., and Levy P.S. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 327 (1992) 76-81
    • (1992) N Engl J Med , vol.327 , pp. 76-81
    • Rich, S.1    Kaufmann, E.2    Levy, P.S.3
  • 18
    • 0027186365 scopus 로고
    • Death in a patient with primary pulmonary hypertension after 20 mg of nifedipine
    • Partanen J., Nieminen M.S., and Luomanmäki K. Death in a patient with primary pulmonary hypertension after 20 mg of nifedipine. N Engl J Med 329 (1993) 812
    • (1993) N Engl J Med , vol.329 , pp. 812
    • Partanen, J.1    Nieminen, M.S.2    Luomanmäki, K.3
  • 19
    • 67649588196 scopus 로고    scopus 로고
    • Updated evidence-based treatment algorithm in pulmonary arterial hypertension
    • Barst R.J., Gibbs J.S., Ghofrani H.A., et al. Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol 54 (2009) S78-S84
    • (2009) J Am Coll Cardiol , vol.54
    • Barst, R.J.1    Gibbs, J.S.2    Ghofrani, H.A.3
  • 20
    • 0024805220 scopus 로고
    • Pathophysiological mechanisms underlying the adverse effects of calcium channel-blocking drugs in patients with chronic heart failure
    • Packer M. Pathophysiological mechanisms underlying the adverse effects of calcium channel-blocking drugs in patients with chronic heart failure. Circulation 80 (1989) IV59-IV67
    • (1989) Circulation , vol.80
    • Packer, M.1
  • 21
    • 77349100424 scopus 로고    scopus 로고
    • General therapeutic approach and traditional therapies
    • Hill N.S., and Farber H.W. (Eds), Humama Press, New Jersey
    • Hill N.S., and Klings E.S. General therapeutic approach and traditional therapies. In: Hill N.S., and Farber H.W. (Eds). Contemporary cardiology: pulmonary hypertension (2008), Humama Press, New Jersey
    • (2008) Contemporary cardiology: pulmonary hypertension
    • Hill, N.S.1    Klings, E.S.2
  • 22
    • 20544448927 scopus 로고    scopus 로고
    • Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension
    • Sitbon O., Humbert M., Jaïs X., et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation 111 (2005) 3105-3111
    • (2005) Circulation , vol.111 , pp. 3105-3111
    • Sitbon, O.1    Humbert, M.2    Jaïs, X.3
  • 23
    • 0034803780 scopus 로고    scopus 로고
    • Medical therapy of pulmonary hypertension. Conventional therapies
    • Naeije R., and Vachiéry J.L. Medical therapy of pulmonary hypertension. Conventional therapies. Clin Chest Med 22 (2001) 517-527
    • (2001) Clin Chest Med , vol.22 , pp. 517-527
    • Naeije, R.1    Vachiéry, J.L.2
  • 24
    • 1342288852 scopus 로고    scopus 로고
    • Clinical value of vasodilator test with inhaled nitric oxide for predicting long-term response to oral vasodilators in pulmonary hypertension
    • Morales-Blanhir J., Santos S., de Jover L., et al. Clinical value of vasodilator test with inhaled nitric oxide for predicting long-term response to oral vasodilators in pulmonary hypertension. Respir Med 98 (2004) 225-234
    • (2004) Respir Med , vol.98 , pp. 225-234
    • Morales-Blanhir, J.1    Santos, S.2    de Jover, L.3
  • 25
    • 77349125202 scopus 로고    scopus 로고
    • Reponse to inhaled nitric oxide (iNO) does not predict long term mortality in pulmonary arterial hypertension (PAH)
    • Rubenfire M., Krishnan S., and Montgomery D. Reponse to inhaled nitric oxide (iNO) does not predict long term mortality in pulmonary arterial hypertension (PAH). Am J Respir Crit Care Med 179 (2009) A2668
    • (2009) Am J Respir Crit Care Med , vol.179
    • Rubenfire, M.1    Krishnan, S.2    Montgomery, D.3
  • 26
    • 0030024879 scopus 로고    scopus 로고
    • Clinical significance of the pulmonary vasodilator response during short-term infusion of prostacyclin in primary pulmonary hypertension
    • Raffy O., Azarian R., Brenot F., et al. Clinical significance of the pulmonary vasodilator response during short-term infusion of prostacyclin in primary pulmonary hypertension. Circulation 93 (1996) 484-488
    • (1996) Circulation , vol.93 , pp. 484-488
    • Raffy, O.1    Azarian, R.2    Brenot, F.3
  • 27
    • 0033537630 scopus 로고    scopus 로고
    • Vasodilator therapy for primary pulmonary hypertension in children
    • Barst R.J., Maislin G., and Fishman A.P. Vasodilator therapy for primary pulmonary hypertension in children. Circulation 99 (1999) 1197-1208
    • (1999) Circulation , vol.99 , pp. 1197-1208
    • Barst, R.J.1    Maislin, G.2    Fishman, A.P.3
  • 28
    • 0032190635 scopus 로고    scopus 로고
    • Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine
    • Ricciardi M.J., Knight B.P., Martinez F.J., and Rubenfire M. Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine. J Am Coll Cardiol 32 (1998) 1068-1073
    • (1998) J Am Coll Cardiol , vol.32 , pp. 1068-1073
    • Ricciardi, M.J.1    Knight, B.P.2    Martinez, F.J.3    Rubenfire, M.4
  • 29
    • 0028888649 scopus 로고
    • Inhaled nitric oxide as a screening vasodilator agent in primary pulmonary hypertension. A dose-response study and comparison with prostacyclin
    • Sitbon O., Brenot F., Denjean A., et al. Inhaled nitric oxide as a screening vasodilator agent in primary pulmonary hypertension. A dose-response study and comparison with prostacyclin. Am J Respir Crit Care Med 151 (1995) 384-389
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 384-389
    • Sitbon, O.1    Brenot, F.2    Denjean, A.3
  • 30
    • 0023238042 scopus 로고
    • High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy
    • Rich S., and Brundage B.H. High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy. Circulation 76 (1987) 135-141
    • (1987) Circulation , vol.76 , pp. 135-141
    • Rich, S.1    Brundage, B.H.2
  • 31
    • 0021917699 scopus 로고
    • Magnitude and implications of spontaneous hemodynamic variability in primary pulmonary hypertension
    • Rich S., D'Alonzo G.E., Dantzker D.R., and Levy P.S. Magnitude and implications of spontaneous hemodynamic variability in primary pulmonary hypertension. Am J Cardiol 55 (1985) 159-163
    • (1985) Am J Cardiol , vol.55 , pp. 159-163
    • Rich, S.1    D'Alonzo, G.E.2    Dantzker, D.R.3    Levy, P.S.4
  • 32
    • 0021828193 scopus 로고
    • The effect of vasodilator therapy on the clinical outcome of patients with primary pulmonary hypertension
    • Rich S., Brundage B.H., and Levy P.S. The effect of vasodilator therapy on the clinical outcome of patients with primary pulmonary hypertension. Circulation 71 (1985) 1191-1196
    • (1985) Circulation , vol.71 , pp. 1191-1196
    • Rich, S.1    Brundage, B.H.2    Levy, P.S.3
  • 33
    • 23844493872 scopus 로고    scopus 로고
    • Acute vasodilator test in pulmonary arterial hypertension: evaluation of two response criteria
    • Costa E.L., Jardim C., Bogossian H.B., Amato M.B., Carvalho C.R., and Souza R. Acute vasodilator test in pulmonary arterial hypertension: evaluation of two response criteria. Vascul Pharmacol 43 (2005) 143-147
    • (2005) Vascul Pharmacol , vol.43 , pp. 143-147
    • Costa, E.L.1    Jardim, C.2    Bogossian, H.B.3    Amato, M.B.4    Carvalho, C.R.5    Souza, R.6
  • 34
    • 0023615359 scopus 로고
    • Primary pulmonary hypertension. A national prospective study
    • Rich S., Dantzker D.R., Ayres S.M., et al. Primary pulmonary hypertension. A national prospective study. Ann Intern Med 107 (1987) 216-223
    • (1987) Ann Intern Med , vol.107 , pp. 216-223
    • Rich, S.1    Dantzker, D.R.2    Ayres, S.M.3
  • 35
    • 0024449294 scopus 로고
    • Histopathology of primary pulmonary hypertension. A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the National Heart, Lung, and Blood Institute, Primary Pulmonary Hypertension Registry
    • Pietra G.G., Edwards W.D., Kay J.M., et al. Histopathology of primary pulmonary hypertension. A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the National Heart, Lung, and Blood Institute, Primary Pulmonary Hypertension Registry. Circulation 80 (1989) 1198-1206
    • (1989) Circulation , vol.80 , pp. 1198-1206
    • Pietra, G.G.1    Edwards, W.D.2    Kay, J.M.3
  • 36
    • 0022000872 scopus 로고
    • Primary pulmonary hypertension: a histopathologic study of 80 cases
    • Bjornsson J., and Edwards W.D. Primary pulmonary hypertension: a histopathologic study of 80 cases. Mayo Clin Proc 60 (1985) 16-25
    • (1985) Mayo Clin Proc , vol.60 , pp. 16-25
    • Bjornsson, J.1    Edwards, W.D.2
  • 37
    • 0000110162 scopus 로고
    • Primary pulmonary hypertension: a pathologic study of the lung vessels in 156 clinically diagnosed cases
    • Wagenvoort C.A., and Wagenvoort N. Primary pulmonary hypertension: a pathologic study of the lung vessels in 156 clinically diagnosed cases. Circulation 42 (1970) 1163-1184
    • (1970) Circulation , vol.42 , pp. 1163-1184
    • Wagenvoort, C.A.1    Wagenvoort, N.2
  • 38
    • 0025943997 scopus 로고
    • High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing
    • Rich S., and Kaufmann E. High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing. J Am Coll Cardiol 18 (1991) 1323-1327
    • (1991) J Am Coll Cardiol , vol.18 , pp. 1323-1327
    • Rich, S.1    Kaufmann, E.2
  • 39
    • 0026519377 scopus 로고
    • Comparison of the effects of adenosine and nifedipine in pulmonary hypertension
    • Schrader B.J., Inbar S., Kaufmann L., Vestal R.E., and Rich S. Comparison of the effects of adenosine and nifedipine in pulmonary hypertension. J Am Coll Cardiol 19 (1992) 1060-1064
    • (1992) J Am Coll Cardiol , vol.19 , pp. 1060-1064
    • Schrader, B.J.1    Inbar, S.2    Kaufmann, L.3    Vestal, R.E.4    Rich, S.5
  • 40
    • 0032576672 scopus 로고    scopus 로고
    • Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension
    • McLaughlin V.V., Genthner D.E., Panella M.M., and Rich S. Reduction in pulmonary vascular resistance with long-term epoprostenol (prostacyclin) therapy in primary pulmonary hypertension. N Engl J Med 338 (1998) 273-277
    • (1998) N Engl J Med , vol.338 , pp. 273-277
    • McLaughlin, V.V.1    Genthner, D.E.2    Panella, M.M.3    Rich, S.4
  • 41
    • 37549033243 scopus 로고    scopus 로고
    • A USA-based registry for pulmonary arterial hypertension: 1982-2006
    • Thenappan T., Shah S.J., Rich S., and Gomberg-Maitland M. A USA-based registry for pulmonary arterial hypertension: 1982-2006. Eur Respir J 30 (2007) 1103-1110
    • (2007) Eur Respir J , vol.30 , pp. 1103-1110
    • Thenappan, T.1    Shah, S.J.2    Rich, S.3    Gomberg-Maitland, M.4
  • 42
    • 69249119028 scopus 로고    scopus 로고
    • Iloprost for pulmonary vasodilator testing in idiopathic pulmonary arterial hypertension
    • Jing Z.C., Jiang X., Han Z.Y., et al. Iloprost for pulmonary vasodilator testing in idiopathic pulmonary arterial hypertension. Eur Respir J 33 (2009) 1354-1360
    • (2009) Eur Respir J , vol.33 , pp. 1354-1360
    • Jing, Z.C.1    Jiang, X.2    Han, Z.Y.3
  • 44
    • 54049091919 scopus 로고    scopus 로고
    • Uncertainties in the diagnosis and treatment of pulmonary arterial hypertension
    • Ghofrani H.A., Wilkins M.W., and Rich S. Uncertainties in the diagnosis and treatment of pulmonary arterial hypertension. Circulation 118 (2008) 1195-1201
    • (2008) Circulation , vol.118 , pp. 1195-1201
    • Ghofrani, H.A.1    Wilkins, M.W.2    Rich, S.3
  • 45
    • 77349084214 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: is there a vasoreactive phenotype?
    • Zimmerman P., Brown L., Schmidt J., et al. Pulmonary arterial hypertension: is there a vasoreactive phenotype?. Am J Respir Crit Care Med 179 (2009) A2650
    • (2009) Am J Respir Crit Care Med , vol.179
    • Zimmerman, P.1    Brown, L.2    Schmidt, J.3
  • 46
    • 0023730239 scopus 로고
    • Haemodynamic requirements for an ideal pulmonary vasodilator
    • Widimský J., Morpurgo M., and Jezek V. Haemodynamic requirements for an ideal pulmonary vasodilator. Eur Heart J 9 Suppl. J (1988) 23-28
    • (1988) Eur Heart J , vol.9 , Issue.SUPPL. J , pp. 23-28
    • Widimský, J.1    Morpurgo, M.2    Jezek, V.3
  • 47
    • 0022359912 scopus 로고
    • Comparison of primary plexogenic arteriopathy in adults and children. A morphometric study in 40 patients
    • Yamaki S., and Wagenvoort C.A. Comparison of primary plexogenic arteriopathy in adults and children. A morphometric study in 40 patients. Br Heart J 54 (1985) 428-434
    • (1985) Br Heart J , vol.54 , pp. 428-434
    • Yamaki, S.1    Wagenvoort, C.A.2
  • 48
    • 43949131056 scopus 로고    scopus 로고
    • Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension
    • Rosenzweig E.B., Morse J.H., Knowles J.A., et al. Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension. J Heart Lung Transplant 27 (2008) 668-674
    • (2008) J Heart Lung Transplant , vol.27 , pp. 668-674
    • Rosenzweig, E.B.1    Morse, J.H.2    Knowles, J.A.3
  • 49
    • 0000145994 scopus 로고
    • Pulmonary hypertension with special reference to the vasoconstrictive factor
    • Wood P. Pulmonary hypertension with special reference to the vasoconstrictive factor. Br Heart J 20 (1958) 557-570
    • (1958) Br Heart J , vol.20 , pp. 557-570
    • Wood, P.1
  • 50
    • 0033977505 scopus 로고    scopus 로고
    • A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group
    • Hoeper M.M., Olschewski H., Ghofrani H.A., et al. A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. J Am Coll Cardiol 35 (2000) 176-182
    • (2000) J Am Coll Cardiol , vol.35 , pp. 176-182
    • Hoeper, M.M.1    Olschewski, H.2    Ghofrani, H.A.3
  • 51
    • 0021791023 scopus 로고
    • Vasodilator therapy for primary pulmonary hypertension. Limitations and hazards
    • Packer M. Vasodilator therapy for primary pulmonary hypertension. Limitations and hazards. Ann Intern Med 103 (1985) 258-270
    • (1985) Ann Intern Med , vol.103 , pp. 258-270
    • Packer, M.1
  • 52
    • 0000861708 scopus 로고
    • Inhaled "endothelial derived-relaxing factor" (EDRF) in primary hypertension (PPH)
    • Higenbottam T., Pepke-Zaba J., Scott J., et al. Inhaled "endothelial derived-relaxing factor" (EDRF) in primary hypertension (PPH). Am Rev Resp Dis 137 (1988) A107
    • (1988) Am Rev Resp Dis , vol.137
    • Higenbottam, T.1    Pepke-Zaba, J.2    Scott, J.3
  • 53
    • 0026002659 scopus 로고
    • Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension
    • Pepke-Zaba J., and Higenbottam T.W. Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 338 (1991) 1173-1174
    • (1991) Lancet , vol.338 , pp. 1173-1174
    • Pepke-Zaba, J.1    Higenbottam, T.W.2
  • 54
    • 5644294776 scopus 로고    scopus 로고
    • Inhaled nitric oxide: a selective pulmonary vasodilator: current uses and therapeutic potential
    • IchNOse F., Roberts Jr. J.D., and Zapol W.M. Inhaled nitric oxide: a selective pulmonary vasodilator: current uses and therapeutic potential. Circulation 109 (2004) 3106-3111
    • (2004) Circulation , vol.109 , pp. 3106-3111
    • IchNOse, F.1    Roberts Jr., J.D.2    Zapol, W.M.3
  • 55
    • 0033101528 scopus 로고    scopus 로고
    • Combined effects of nitric oxide and oxygen during acute pulmonary vasodilator testing
    • Atz A.M., Adatia I., Lock J.E., and Wessel D.L. Combined effects of nitric oxide and oxygen during acute pulmonary vasodilator testing. J Am Coll Cardiol 33 (1999) 813-819
    • (1999) J Am Coll Cardiol , vol.33 , pp. 813-819
    • Atz, A.M.1    Adatia, I.2    Lock, J.E.3    Wessel, D.L.4
  • 56
    • 0030955773 scopus 로고    scopus 로고
    • Nitric oxide and prostacyclin as test agents of vasoreactivity in severe precapillary pulmonary hypertension: predictive ability and consequences on haemodynamics and gas exchange
    • Jolliet P., Bulpa P., Thorens J.B., Ritz M., and Chevrolet J.C. Nitric oxide and prostacyclin as test agents of vasoreactivity in severe precapillary pulmonary hypertension: predictive ability and consequences on haemodynamics and gas exchange. Thorax 52 (1997) 369-372
    • (1997) Thorax , vol.52 , pp. 369-372
    • Jolliet, P.1    Bulpa, P.2    Thorens, J.B.3    Ritz, M.4    Chevrolet, J.C.5
  • 57
    • 0037322944 scopus 로고    scopus 로고
    • Assessment of the vasodilator response in primary pulmonary hypertension. Comparing prostacyclin and iloprost administered by either infusion or inhalation
    • Opitz C.F., Wensel R., Bettmann M., et al. Assessment of the vasodilator response in primary pulmonary hypertension. Comparing prostacyclin and iloprost administered by either infusion or inhalation. Eur Heart J 24 (2003) 356-365
    • (2003) Eur Heart J , vol.24 , pp. 356-365
    • Opitz, C.F.1    Wensel, R.2    Bettmann, M.3
  • 58
    • 0025972655 scopus 로고
    • Effects of nitrogen dioxide exposure on pulmonary function and airway reactivity in normal humans
    • Frampton M.W., Morrow P.E., Cox C., Gibb F.R., Speers D.M., and Utell M.J. Effects of nitrogen dioxide exposure on pulmonary function and airway reactivity in normal humans. Am Rev Respir Dis 143 (1991) 522-527
    • (1991) Am Rev Respir Dis , vol.143 , pp. 522-527
    • Frampton, M.W.1    Morrow, P.E.2    Cox, C.3    Gibb, F.R.4    Speers, D.M.5    Utell, M.J.6
  • 59
    • 0032848791 scopus 로고    scopus 로고
    • Inhaled nitric oxide: basic biology and clinical applications
    • Steudel W., Hurford W.E., and Zapol W.M. Inhaled nitric oxide: basic biology and clinical applications. Anesthesiology 91 (1999) 1090-1121
    • (1999) Anesthesiology , vol.91 , pp. 1090-1121
    • Steudel, W.1    Hurford, W.E.2    Zapol, W.M.3
  • 60
    • 0036152551 scopus 로고    scopus 로고
    • Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertension
    • Pearl J.M., Nelson D.P., Raake J.L., et al. Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertension. Crit Care Med 30 (2002) 89-93
    • (2002) Crit Care Med , vol.30 , pp. 89-93
    • Pearl, J.M.1    Nelson, D.P.2    Raake, J.L.3
  • 61
    • 0034440196 scopus 로고    scopus 로고
    • Inhaled nitric oxide and pulmonary vasoreactivity
    • Aranda M., and Pearl R.G. Inhaled nitric oxide and pulmonary vasoreactivity. J Clin Monit Comput 16 (2000) 393-401
    • (2000) J Clin Monit Comput , vol.16 , pp. 393-401
    • Aranda, M.1    Pearl, R.G.2
  • 62
    • 42949166212 scopus 로고    scopus 로고
    • Prostacyclin therapies for the treatment of pulmonary arterial hypertension
    • Gomberg-Maitland M., and Olschewski H. Prostacyclin therapies for the treatment of pulmonary arterial hypertension. Eur Respir J 31 (2008) 891-901
    • (2008) Eur Respir J , vol.31 , pp. 891-901
    • Gomberg-Maitland, M.1    Olschewski, H.2
  • 63
    • 0023846158 scopus 로고
    • Comparison of acute hemodynamic responses to prostacyclin with standard vasodilators in patients with primary pulmonary hypertension
    • Palevsky H.I., and Fishman A.P. Comparison of acute hemodynamic responses to prostacyclin with standard vasodilators in patients with primary pulmonary hypertension. Chest 93 (1988) 179S
    • (1988) Chest , vol.93
    • Palevsky, H.I.1    Fishman, A.P.2
  • 64
    • 0028873863 scopus 로고
    • Comparative acute effects of adenosine and prostacyclin in primary pulmonary hypertension
    • Nootens M., Schrader B., Kaufmann E., Vestal R., Long W., and Rich S. Comparative acute effects of adenosine and prostacyclin in primary pulmonary hypertension. Chest 107 (1995) 54-57
    • (1995) Chest , vol.107 , pp. 54-57
    • Nootens, M.1    Schrader, B.2    Kaufmann, E.3    Vestal, R.4    Long, W.5    Rich, S.6
  • 65
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert M., Sitbon O., and Simonneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 351 (2004) 1425-1436
    • (2004) N Engl J Med , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 66
    • 0030853952 scopus 로고    scopus 로고
    • A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST)
    • Califf R.M., Adams K.F., McKenna W.J., et al. A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST). Am Heart J 134 (1997) 44-54
    • (1997) Am Heart J , vol.134 , pp. 44-54
    • Califf, R.M.1    Adams, K.F.2    McKenna, W.J.3
  • 67
    • 0036682273 scopus 로고    scopus 로고
    • Aerosolized Iloprost Randomized Study Group. Inhaled iloprost for severe pulmonary hypertension
    • Olschewski H., Simonneau G., Galiè N., et al. Aerosolized Iloprost Randomized Study Group. Inhaled iloprost for severe pulmonary hypertension. N Engl J Med 347 (2002) 322-329
    • (2002) N Engl J Med , vol.347 , pp. 322-329
    • Olschewski, H.1    Simonneau, G.2    Galiè, N.3
  • 68
    • 0035845634 scopus 로고    scopus 로고
    • Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension
    • Wilkens H., Guth A., König J., et al. Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension. Circulation 104 (2001) 1218-1222
    • (2001) Circulation , vol.104 , pp. 1218-1222
    • Wilkens, H.1    Guth, A.2    König, J.3
  • 69
    • 0025287791 scopus 로고
    • The pharmacology of adenosine
    • Pelleg A., and Porter R.S. The pharmacology of adenosine. Pharmacotherapy 10 (1990) 157-174
    • (1990) Pharmacotherapy , vol.10 , pp. 157-174
    • Pelleg, A.1    Porter, R.S.2
  • 70
    • 0026091632 scopus 로고
    • Adenosine and selective reduction of pulmonary vascular resistance in primary pulmonary hypertension
    • Reeves J.T., Groves B.M., and Weir E.K. Adenosine and selective reduction of pulmonary vascular resistance in primary pulmonary hypertension. Circulation 84 (1991) 1437-1439
    • (1991) Circulation , vol.84 , pp. 1437-1439
    • Reeves, J.T.1    Groves, B.M.2    Weir, E.K.3
  • 71
    • 0037126044 scopus 로고    scopus 로고
    • Survival in primary pulmonary hypertension: the impact of epoprostenol therapy
    • McLaughlin V.V., Shillington A., and Rich S. Survival in primary pulmonary hypertension: the impact of epoprostenol therapy. Circulation 106 (2002) 1477-1482
    • (2002) Circulation , vol.106 , pp. 1477-1482
    • McLaughlin, V.V.1    Shillington, A.2    Rich, S.3
  • 73
    • 28044466945 scopus 로고    scopus 로고
    • Acute and chronic effects of sildenafil in patients with pulmonary arterial hypertension
    • Preston I.R., Klinger J.R., Houtches J., Nelson D., Farber H.W., and Hill N.S. Acute and chronic effects of sildenafil in patients with pulmonary arterial hypertension. Respir Med 99 (2005) 1501-1510
    • (2005) Respir Med , vol.99 , pp. 1501-1510
    • Preston, I.R.1    Klinger, J.R.2    Houtches, J.3    Nelson, D.4    Farber, H.W.5    Hill, N.S.6
  • 74
    • 0345688647 scopus 로고    scopus 로고
    • Intravenous sildenafil and inhaled nitric oxide: a randomized trial in infants after cardiac surgery
    • Stocker C., Penny D.J., Brizard C.P., Cochrane A.D., Soto R., and Shekerdemian L.S. Intravenous sildenafil and inhaled nitric oxide: a randomized trial in infants after cardiac surgery. Intensive Care Med 29 (2003) 1996-2003
    • (2003) Intensive Care Med , vol.29 , pp. 1996-2003
    • Stocker, C.1    Penny, D.J.2    Brizard, C.P.3    Cochrane, A.D.4    Soto, R.5    Shekerdemian, L.S.6
  • 75
    • 0024345771 scopus 로고
    • Is it ethical to administer vasodilator drugs to patients with primary pulmonary hypertension?
    • Packer M. Is it ethical to administer vasodilator drugs to patients with primary pulmonary hypertension?. Chest 95 (1989) 1173-1175
    • (1989) Chest , vol.95 , pp. 1173-1175
    • Packer, M.1
  • 76
    • 20544443287 scopus 로고    scopus 로고
    • Acute vasodilator responsiveness and long-term response to calcium-channel blockers in different forms of pulmonary arterial hypertension
    • Sitbon O., Humbert M., Jais X., et al. Acute vasodilator responsiveness and long-term response to calcium-channel blockers in different forms of pulmonary arterial hypertension. Am J Respir Crit Care Med 169 (2004) A210
    • (2004) Am J Respir Crit Care Med , vol.169
    • Sitbon, O.1    Humbert, M.2    Jais, X.3
  • 77
    • 33745125419 scopus 로고    scopus 로고
    • Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension
    • Elliott C.G., Glissmeyer E.W., Havlena G.T., et al. Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension. Circulation 113 (2006) 2509-2515
    • (2006) Circulation , vol.113 , pp. 2509-2515
    • Elliott, C.G.1    Glissmeyer, E.W.2    Havlena, G.T.3
  • 78
    • 2942581061 scopus 로고    scopus 로고
    • Genetic basis of pulmonary arterial hypertension: current understanding and future directions
    • Newman J.H., Trembath R.C., Morse J.A., et al. Genetic basis of pulmonary arterial hypertension: current understanding and future directions. J Am Coll Cardiol 43 (2004) 33S-39S
    • (2004) J Am Coll Cardiol , vol.43
    • Newman, J.H.1    Trembath, R.C.2    Morse, J.A.3
  • 79
    • 44949197649 scopus 로고    scopus 로고
    • Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation
    • Sztrymf B., Coulet F., Girerd B., et al. Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation. Am J Respir Crit Care Med 177 (2008) 1377-1383
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1377-1383
    • Sztrymf, B.1    Coulet, F.2    Girerd, B.3
  • 80
    • 0031718736 scopus 로고    scopus 로고
    • Primary pulmonary hypertension associated with the use of fenfluramine derivatives
    • Simonneau G., Fartoukh M., Sitbon O., et al. Primary pulmonary hypertension associated with the use of fenfluramine derivatives. Chest 114 (1998) 195S-199S
    • (1998) Chest , vol.114
    • Simonneau, G.1    Fartoukh, M.2    Sitbon, O.3
  • 81
    • 0033512182 scopus 로고    scopus 로고
    • Systemic sclerosis-associated pulmonary hypertension: short- and long-term effects of epoprostenol (prostacyclin)
    • Klings E.S., Hill N.S., Ieong M.H., Simms R.W., Korn J.H., and Farber H.W. Systemic sclerosis-associated pulmonary hypertension: short- and long-term effects of epoprostenol (prostacyclin). Arthritis Rheum 42 (1999) 2638-2645
    • (1999) Arthritis Rheum , vol.42 , pp. 2638-2645
    • Klings, E.S.1    Hill, N.S.2    Ieong, M.H.3    Simms, R.W.4    Korn, J.H.5    Farber, H.W.6
  • 82
    • 0026327195 scopus 로고
    • Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease
    • Alpert M.A., Pressly T.A., Mukerji V., et al. Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. Am J Cardiol 68 (1991) 1687-1691
    • (1991) Am J Cardiol , vol.68 , pp. 1687-1691
    • Alpert, M.A.1    Pressly, T.A.2    Mukerji, V.3
  • 83
    • 0028129280 scopus 로고
    • Combined effects of diltiazem and oxygen in pulmonary hypertension of mixed connective tissue disease
    • ShNOhara S., Murata I., Yamada H., et al. Combined effects of diltiazem and oxygen in pulmonary hypertension of mixed connective tissue disease. J Rheumatol 21 (1994) 1763-1765
    • (1994) J Rheumatol , vol.21 , pp. 1763-1765
    • ShNOhara, S.1    Murata, I.2    Yamada, H.3
  • 84
    • 0025863262 scopus 로고
    • Cardiopulmonary hemodynamics in systemic sclerosis and response to nifedipine and captopril
    • Sfikakis P.P., Kyriakidis M.K., Vergos C.G., et al. Cardiopulmonary hemodynamics in systemic sclerosis and response to nifedipine and captopril. Am J Med 90 (1991) 541-546
    • (1991) Am J Med , vol.90 , pp. 541-546
    • Sfikakis, P.P.1    Kyriakidis, M.K.2    Vergos, C.G.3
  • 85
    • 0029838867 scopus 로고    scopus 로고
    • Acute hemodynamic responses to inhaled nitric oxide in patients with limited scleroderma and isolated pulmonary hypertension
    • Williamson D.J., Hayward C., Rogers P., et al. Acute hemodynamic responses to inhaled nitric oxide in patients with limited scleroderma and isolated pulmonary hypertension. Circulation 94 (1996) 477-482
    • (1996) Circulation , vol.94 , pp. 477-482
    • Williamson, D.J.1    Hayward, C.2    Rogers, P.3
  • 86
    • 0033782458 scopus 로고    scopus 로고
    • Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension
    • Strange C., Bolster M., Mazur J., Taylor M., Gossage J.R., and Silver R. Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension. Chest 118 (2000) 1077-1082
    • (2000) Chest , vol.118 , pp. 1077-1082
    • Strange, C.1    Bolster, M.2    Mazur, J.3    Taylor, M.4    Gossage, J.R.5    Silver, R.6
  • 87
    • 39749156384 scopus 로고    scopus 로고
    • Immunosuppressive therapy in lupus- and mixed connective tissue disease-associated pulmonary arterial hypertension: a retrospective analysis of twenty-three cases
    • Jais X., Launay D., Yaici A., et al. Immunosuppressive therapy in lupus- and mixed connective tissue disease-associated pulmonary arterial hypertension: a retrospective analysis of twenty-three cases. Arthritis Rheum 58 (2008) 521-531
    • (2008) Arthritis Rheum , vol.58 , pp. 521-531
    • Jais, X.1    Launay, D.2    Yaici, A.3
  • 88
    • 0032939165 scopus 로고    scopus 로고
    • Pulmonary edema during acute infusion of epoprostenol in a patient with pulmonary hypertension and limited scleroderma
    • Farber H.W., Graven K.K., Kokolski G., and Korn J.H. Pulmonary edema during acute infusion of epoprostenol in a patient with pulmonary hypertension and limited scleroderma. J Rheumatol 26 (1999) 1195-1196
    • (1999) J Rheumatol , vol.26 , pp. 1195-1196
    • Farber, H.W.1    Graven, K.K.2    Kokolski, G.3    Korn, J.H.4
  • 89
    • 0036167535 scopus 로고    scopus 로고
    • Pulmonary edema caused by inhaled nitric oxide therapy in two patients with pulmonary hypertension associated with the CREST syndrome
    • Preston I.R., Klinger J.R., Houtchens J., Nelson D., Mehta S., and Hill N.S. Pulmonary edema caused by inhaled nitric oxide therapy in two patients with pulmonary hypertension associated with the CREST syndrome. Chest 121 (2002) 656-659
    • (2002) Chest , vol.121 , pp. 656-659
    • Preston, I.R.1    Klinger, J.R.2    Houtchens, J.3    Nelson, D.4    Mehta, S.5    Hill, N.S.6
  • 90
    • 0033679134 scopus 로고    scopus 로고
    • Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension
    • Aguilar R.V., and Farber H.W. Epoprostenol (prostacyclin) therapy in HIV-associated pulmonary hypertension. Am J Respir Crit Care Med 162 (2000) 1846-1850
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 1846-1850
    • Aguilar, R.V.1    Farber, H.W.2
  • 91
    • 0028298825 scopus 로고
    • Pulmonary hypertension in patients with human immunodeficiency virus infection. Comparison with primary pulmonary hypertension
    • Petitpretz P., Brenot F., Azarian R., et al. Pulmonary hypertension in patients with human immunodeficiency virus infection. Comparison with primary pulmonary hypertension. Circulation 89 (1994) 2722-2727
    • (1994) Circulation , vol.89 , pp. 2722-2727
    • Petitpretz, P.1    Brenot, F.2    Azarian, R.3
  • 92
    • 15444354123 scopus 로고    scopus 로고
    • HIV-associated primary pulmonary hypertension. A case control study. Swiss HIV Cohort Study
    • Opravil M., Pechère M., Speich R., et al. HIV-associated primary pulmonary hypertension. A case control study. Swiss HIV Cohort Study. Am J Respir Crit Care Med 155 (1997) 990-995
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 990-995
    • Opravil, M.1    Pechère, M.2    Speich, R.3
  • 93
    • 0028983911 scopus 로고
    • Comparative studies of hemodynamics under prostacyclin and nifedipine in patients with Eisenmenger syndrome
    • Gildein H.P., Wildberg A., and Mocellin R. Comparative studies of hemodynamics under prostacyclin and nifedipine in patients with Eisenmenger syndrome. Z Kardiol 84 (1995) 55-63
    • (1995) Z Kardiol , vol.84 , pp. 55-63
    • Gildein, H.P.1    Wildberg, A.2    Mocellin, R.3
  • 94
    • 34250680970 scopus 로고    scopus 로고
    • Long-term follow-up of portopulmonary hypertension: effect of treatment with epoprostenol
    • Fix O.K., Bass N.M., De Marco T., and Merriman R.B. Long-term follow-up of portopulmonary hypertension: effect of treatment with epoprostenol. Liver Transpl 13 (2007) 875-885
    • (2007) Liver Transpl , vol.13 , pp. 875-885
    • Fix, O.K.1    Bass, N.M.2    De Marco, T.3    Merriman, R.B.4
  • 95
    • 0028839874 scopus 로고
    • Activation of thromboxane and prostacyclin receptors elicits opposing effects on vascular smooth muscle cell growth and mitogen-activated protein kinase signaling cascades
    • Jones D.A., Benjamin C.W., and Linseman D.A. Activation of thromboxane and prostacyclin receptors elicits opposing effects on vascular smooth muscle cell growth and mitogen-activated protein kinase signaling cascades. Mol Pharmacol 48 (1995) 890-896
    • (1995) Mol Pharmacol , vol.48 , pp. 890-896
    • Jones, D.A.1    Benjamin, C.W.2    Linseman, D.A.3
  • 96
    • 58849130566 scopus 로고    scopus 로고
    • Long-term effects of bosentan in patients with HIV-associated pulmonary arterial hypertension
    • Degano B., Yaïci1 A., Le Pavec1 J., et al. Long-term effects of bosentan in patients with HIV-associated pulmonary arterial hypertension. Eur Respir J 33 (2009) 92-98
    • (2009) Eur Respir J , vol.33 , pp. 92-98
    • Degano, B.1    Yaïci1, A.2    Le Pavec1, J.3
  • 97
    • 33746206340 scopus 로고    scopus 로고
    • Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study
    • Galiè N., Beghetti M., Gatzoulis M.A., et al. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 114 (2006) 48-54
    • (2006) Circulation , vol.114 , pp. 48-54
    • Galiè, N.1    Beghetti, M.2    Gatzoulis, M.A.3
  • 98
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial
    • Badesch D.B., Tapson V.F., McGoon M.D., et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med 132 (2000) 425-434
    • (2000) Ann Intern Med , vol.132 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 99
    • 0032783593 scopus 로고    scopus 로고
    • Combination of inhaled nitric oxide and intravenous prostacyclin for successful treatment of severe pulmonary hypertension in a patient with acute respiratory distress syndrome
    • Kuhlen R., Walbert E., Fränkel P., Thaden S., Behrendt W., and Rossaint R. Combination of inhaled nitric oxide and intravenous prostacyclin for successful treatment of severe pulmonary hypertension in a patient with acute respiratory distress syndrome. Intensive Care Med 25 (1999) 752-754
    • (1999) Intensive Care Med , vol.25 , pp. 752-754
    • Kuhlen, R.1    Walbert, E.2    Fränkel, P.3    Thaden, S.4    Behrendt, W.5    Rossaint, R.6
  • 100
    • 0032976140 scopus 로고    scopus 로고
    • Combined therapy with inhaled nitric oxide and intravenous vasodilators during acute and chronic experimental pulmonary hypertension
    • Aranda M., Bradford K.K., and Pearl R.G. Combined therapy with inhaled nitric oxide and intravenous vasodilators during acute and chronic experimental pulmonary hypertension. Anesth Analg 89 (1999) 152-158
    • (1999) Anesth Analg , vol.89 , pp. 152-158
    • Aranda, M.1    Bradford, K.K.2    Pearl, R.G.3
  • 101
    • 54549125950 scopus 로고    scopus 로고
    • Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial
    • Simonneau G., Rubin L.J., Galiè N., et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 149 (2008) 521-530
    • (2008) Ann Intern Med , vol.149 , pp. 521-530
    • Simonneau, G.1    Rubin, L.J.2    Galiè, N.3
  • 102
    • 0023127961 scopus 로고
    • Reversibility of primary pulmonary hypertension during six years of treatment with oral diazoxide
    • Chan N.S., McLay J., and Kenmure A.C. Reversibility of primary pulmonary hypertension during six years of treatment with oral diazoxide. Br Heart J 57 (1987) 207-209
    • (1987) Br Heart J , vol.57 , pp. 207-209
    • Chan, N.S.1    McLay, J.2    Kenmure, A.C.3
  • 103
    • 0027401257 scopus 로고
    • Effects of adenosine in combination with calcium channel blockers in patients with primary pulmonary hypertension
    • Inbar S., Schrader B.J., Kaufmann E., Vestal R.E., and Rich S. Effects of adenosine in combination with calcium channel blockers in patients with primary pulmonary hypertension. J Am Coll Cardiol 21 (1993) 413-418
    • (1993) J Am Coll Cardiol , vol.21 , pp. 413-418
    • Inbar, S.1    Schrader, B.J.2    Kaufmann, E.3    Vestal, R.E.4    Rich, S.5
  • 104
    • 0017233694 scopus 로고
    • Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs
    • McMurtry I.F., Davidson A.B., Reeves J.T., and Grover R.F. Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs. Circ Res 38 (1976) 99-104
    • (1976) Circ Res , vol.38 , pp. 99-104
    • McMurtry, I.F.1    Davidson, A.B.2    Reeves, J.T.3    Grover, R.F.4
  • 105
    • 0019382727 scopus 로고
    • Primary pulmonary hypertension: beneficial therapy with diltiazem
    • Kambara H., Fujimoto K., Wakabayashi A., and Kawai C. Primary pulmonary hypertension: beneficial therapy with diltiazem. Am Heart J 101 (1981) 230-231
    • (1981) Am Heart J , vol.101 , pp. 230-231
    • Kambara, H.1    Fujimoto, K.2    Wakabayashi, A.3    Kawai, C.4
  • 106
    • 77349086666 scopus 로고    scopus 로고
    • Diagnostic work up of pulmonary arterial hypertension (PAH): data from the quality enhancement research initiative (QuERI)
    • Oudiz R.J., Casanova A., and Rubin L.J. Diagnostic work up of pulmonary arterial hypertension (PAH): data from the quality enhancement research initiative (QuERI). Am J Respir Crit Care Med 179 (2009) A2666
    • (2009) Am J Respir Crit Care Med , vol.179
    • Oudiz, R.J.1    Casanova, A.2    Rubin, L.J.3
  • 107
    • 73049111879 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension (PAH): data from the quality enhancement research initiative
    • McLaughlin V., Langer A., Dragomir A., et al. Treatment of pulmonary arterial hypertension (PAH): data from the quality enhancement research initiative. Am J Respir Crit Care Med 179 (2009) A1043
    • (2009) Am J Respir Crit Care Med , vol.179
    • McLaughlin, V.1    Langer, A.2    Dragomir, A.3
  • 108
    • 0021797206 scopus 로고
    • Pulmonary edema with nifedipine in primary pulmonary hypertension
    • Batra A.K., Segall P.H., and Ahmed T. Pulmonary edema with nifedipine in primary pulmonary hypertension. Respiration 47 (1985) 161-163
    • (1985) Respiration , vol.47 , pp. 161-163
    • Batra, A.K.1    Segall, P.H.2    Ahmed, T.3
  • 109
    • 0021686916 scopus 로고
    • Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease
    • Packer M., Medina N., and Yushak M. Adverse hemodynamic and clinical effects of calcium channel blockade in pulmonary hypertension secondary to obliterative pulmonary vascular disease. J Am Coll Cardiol 4 (1984) 890-901
    • (1984) J Am Coll Cardiol , vol.4 , pp. 890-901
    • Packer, M.1    Medina, N.2    Yushak, M.3
  • 110
    • 0021931473 scopus 로고
    • Hypotension and sinus arrest with nifedipine in pulmonary hypertension
    • Aromatorio G.J., Uretsky B.F., and Reddy P.S. Hypotension and sinus arrest with nifedipine in pulmonary hypertension. Chest 87 (1985) 265-267
    • (1985) Chest , vol.87 , pp. 265-267
    • Aromatorio, G.J.1    Uretsky, B.F.2    Reddy, P.S.3
  • 111
    • 0020625012 scopus 로고
    • Fatal outcome following nifedipine for pulmonary hypertension
    • Farber H.W., Karlinsky J.B., and Faling L.J. Fatal outcome following nifedipine for pulmonary hypertension. Chest 83 (1983) 708-709
    • (1983) Chest , vol.83 , pp. 708-709
    • Farber, H.W.1    Karlinsky, J.B.2    Faling, L.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.