Effect of survivin-siRNA on drug sensitivity of osteosarcoma cell line MG-63

Chinese Journal of Cancer Research

Volumn 22, Issue 1, 2010, Pages 68-72

  Wang, Jing Wei ^a   Liu, Yi ^b   Tian, Hai Mei ^b   Zhang, Wei ^b  

^a Tangshan Workers Hospital   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Drug sensitivity; Osteosarcoma; RNAi; SiRNA; Survivin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CISPLATIN; DOXORUBICIN; MESSENGER RNA; SMALL INTERFERING RNA; SMALL INTERFERING RNA 1; SMALL INTERFERING RNA 2; SURVIVIN; TUMOR MARKER; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG SYNTHESIS; DRUG TARGETING; FEASIBILITY STUDY; FLOW CYTOMETRY; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; OSTEOSARCOMA; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 77249122725     PISSN: 10009604     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11670-010-0068-x     Document Type: Article

References (14)

1. P. Picci S. Ferrari G. Bacci, et al. 1994 Treatment recommendations for osteosarcoma and adult soft-tissue sarcomas [J] Drugs 47 82 92 10.2165/00003495-199447010-00006 1:STN:280:DyaK2c7nvVahtQ%3D%3D 7510623
2. M. Ikeguchi N. Kaibara 2002 Survivin messenger RNA expression is a good prognostic biomarker for oesophageal carcinoma [J] Br J Cancer 87 883 887 10.1038/sj.bjc.6600546 1:CAS:528:DC%2BD38Xns1Gnt7k%3D 12373603 (Pubitemid 35252964)
3. N.R. Wall D.S. O'Connor J. Plescia, et al. 2003 Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis [J] Cancer Res 63 230 235 1:CAS:528:DC%2BD3sXjvFKnsQ%3D%3D 12517802
4. G. Ambrosini C. Adida D.C. Altieri 1997 A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma [J] Nat Med 3 917 921 10.1038/nm0897-917 1:CAS:528:DyaK2sXltVylt7w%3D 9256286 (Pubitemid 27353455)
5. C. R-del J. Haas A. Groth, et al. 2003 Spontaneous and radiation-induced apoptosis in colorectal carcinoma cells with different intrinsic radiosensitivities: survivin as a radioresistance factor [J] Int J Radiat Oncol Biol Phys 55 1341 1347
6. R.A. Olie A.P. Sim-es-Wüst B. Baumann, et al. 2000 A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy [J] Cancer Res 60 2805 2809 1:CAS:528:DC%2BD3cXjvFOlsLo%3D 10850418
7. N. Zaffaroni M.G. Daidone 2002 Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic interventions [J] Drug Resist Updat 5 65 72 10.1016/S1368-7646(02)00049-3 1:CAS:528: DC%2BD38XosFKjurg%3D 12135582 (Pubitemid 35033448)
8. G. Ambrosini C. Adida D.C. Altieri 1997 A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma [J] Nat Med 3 917 921 10.1038/nm0897-917 1:CAS:528:DyaK2sXltVylt7w%3D 9256286 (Pubitemid 27353455)
9. F. Li G. Ambrosini E.Y. Chu, et al. 1998 Control of apoptosis and mitotic spindle checkpoint by survivin [J] Nature 396 580 584 10.1038/25141 1:CAS:528:DyaK1cXotVWns70%3D 9859993 (Pubitemid 28563719)
10. K. Asanuma R. Moriai T. Yajima, et al. 2000 Survivin as a radioresistance factor in pancreatic cancer [J] Jpn J Cancer Res 91 1204 1209 1:CAS:528:DC%2BD3cXosVGrsbo%3D 11092988
11. M. Ikeguchi J. Liu N. Kaibara 2002 Expression of survivin mRNA and protein in gastric cancer cell line (MKN-45) during cisplatin treatment [J] Apoptosis 7 23 29 10.1023/A:1013556727182 1:CAS:528:DC%2BD38Xit1aisb0%3D 11773702 (Pubitemid 34145388)
12. E. Bernstein A.M. Denli G.J. Hannon 2001 The rest is silence [J] RNA 7 1509 1521 1:CAS:528:DC%2BD3MXos1Khtbc%3D 11720281
13. S.M. Elbashir J. Harborth W. Lendeckel, et al. 2001 Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells [J] Nature 411 494 498 10.1038/35078107 1:CAS:528:DC%2BD3MXkt1ejt7Y%3D 11373684 (Pubitemid 32494397)
14. N.S. Williams R.B. Gaynor S. Scoggin, et al. 2003 Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference [J] Clin Cancer Res 9 931 946 1:CAS:528:DC%2BD3sXhvFKiurs%3D 12631590