메뉴 건너뛰기




Volumn 12, Issue 1, 2010, Pages 45-52

Antibodies to serine proteases in the antiphospholipid syndrome

Author keywords

Activated protein C; Hemostasis; Plasmin; Thrombin; Thrombosis

Indexed keywords

ACTIVATED PROTEIN C; BETA2 GLYCOPROTEIN 1; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 9A; ENZYME ANTIBODY; IMMUNOGLOBULIN G; PHOSPHOLIPID ANTIBODY; PLASMIN; SERINE PROTEINASE; SERINE PROTEINASE ANTIBODY; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

EID: 77249100694     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-009-0072-7     Document Type: Review
Times cited : (31)

References (50)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • 10.1111/j.1538-7836.2006.01753.x 1:CAS:528:DC%2BD28XisVSjuro%3D 16420554
    • S Miyakis MD Lockshin T Atsumi, et al. 2006 International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) J Thromb Haemost 4 295 306 10.1111/j.1538-7836. 2006.01753.x 1:CAS:528:DC%2BD28XisVSjuro%3D 16420554
    • (2006) J Thromb Haemost , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3
  • 2
    • 33747807163 scopus 로고    scopus 로고
    • Diagnosis of antiphospholipid syndrome
    • 10.1038/ncprheum0017 1:CAS:528:DC%2BD28Xis1artbc%3D 16932626
    • ML Bertolaccini MA Khamashta GR Hughes 2005 Diagnosis of antiphospholipid syndrome Nat Clin Pract Rheumatol 1 40 46 10.1038/ncprheum0017 1:CAS:528:DC%2BD28Xis1artbc%3D 16932626
    • (2005) Nat Clin Pract Rheumatol , vol.1 , pp. 40-46
    • Bertolaccini, M.L.1    Khamashta, M.A.2    Hughes, G.R.3
  • 3
    • 50249189294 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the antiphospholipid syndrome: Pathogenic mechanisms
    • 10.1055/s-0028-1082267 1:CAS:528:DC%2BD1MXnvF2gur8%3D 18720303
    • SS Pierangeli PP Chen E Raschi, et al. 2008 Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms Semin Thromb Hemost 34 236 250 10.1055/s-0028-1082267 1:CAS:528:DC%2BD1MXnvF2gur8%3D 18720303
    • (2008) Semin Thromb Hemost , vol.34 , pp. 236-250
    • Pierangeli, S.S.1    Chen, P.P.2    Raschi, E.3
  • 4
    • 44849126725 scopus 로고    scopus 로고
    • New developments in lupus-associated antiphospholipid syndrome
    • DOI 10.1177/0961203308090032, Proceedings of the 7th european Lupus Meeting
    • MD Lockshin RH Derksen 2008 New developments in lupus-associated antiphospholipid syndrome Lupus 17 443 446 10.1177/0961203308090032 1:STN:280:DC%2BD1czislajsg%3D%3D 18490424 (Pubitemid 351798724)
    • (2008) Lupus , vol.17 , Issue.SPEC. ISS. , pp. 443-446
    • Lockshin, M.D.1    Ronald Derksen, H.W.M.2
  • 5
    • 0031975978 scopus 로고    scopus 로고
    • An antiphospholipid wet workshop: 7th International Symposium on Antiphospholipid Antibodies
    • 1:STN:280:DyaK1c7hslChtw%3D%3D 9458221
    • SS Pierangeli M Stewart LK Silva EN Harris 1998 An antiphospholipid wet workshop: 7th International Symposium on Antiphospholipid Antibodies J Rheumatol 25 156 160 1:STN:280:DyaK1c7hslChtw%3D%3D 9458221
    • (1998) J Rheumatol , vol.25 , pp. 156-160
    • Pierangeli, S.S.1    Stewart, M.2    Silva, L.K.3    Harris, E.N.4
  • 6
    • 0029610027 scopus 로고
    • Laboratory identification of lupus anticoagulants: Results of the Second International Workshop for identification of lupus anticoagulants. on behalf of the subcommittee on lupus anticoagulants antiphospholipid antibodies of the ISTH
    • 1:CAS:528:DyaK28Xjtlynuw%3D%3D 8772243
    • JT Brandt LK Barna DA Triplett 1995 Laboratory identification of lupus anticoagulants: results of the Second International Workshop for identification of lupus anticoagulants. On behalf of the subcommittee on lupus anticoagulants antiphospholipid antibodies of the ISTH Thromb Haemost 74 1597 1603 1:CAS:528:DyaK28Xjtlynuw%3D%3D 8772243
    • (1995) Thromb Haemost , vol.74 , pp. 1597-1603
    • Brandt, J.T.1    Barna, L.K.2    Triplett, D.A.3
  • 7
    • 0023772539 scopus 로고
    • Anti-prothrombin antibodies and the lupus anticoagulant
    • 1:STN:280:DyaL1c3psVejsA%3D%3D 2456797
    • RA Fleck SI Rapaport LV Rao 1988 Anti-prothrombin antibodies and the lupus anticoagulant Blood 72 512 519 1:STN:280:DyaL1c3psVejsA%3D%3D 2456797
    • (1988) Blood , vol.72 , pp. 512-519
    • Fleck, R.A.1    Rapaport, S.I.2    Rao, L.V.3
  • 9
    • 0027253088 scopus 로고
    • Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism?
    • 1:CAS:528:DyaK3sXkslSjtrs%3D 8166780
    • JD Oosting RH Derksen IW Bobbink, et al. 1993 Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: an explanation for their pathogenic mechanism? Blood 81 2618 2625 1:CAS:528:DyaK3sXkslSjtrs%3D 8166780
    • (1993) Blood , vol.81 , pp. 2618-2625
    • Oosting, J.D.1    Derksen, R.H.2    Bobbink, I.W.3
  • 10
    • 0028209969 scopus 로고
    • Functional and binding studies of the roles of prothrombin and b2-glycoprotein i in the expression of lupus anticoagulant activity
    • 1:CAS:528:DyaK2cXltVKgt78%3D 8180383
    • P Permpikul LV Rao SI Rapaport 1994 Functional and binding studies of the roles of prothrombin and b2-glycoprotein I in the expression of lupus anticoagulant activity Blood 83 2878 2892 1:CAS:528:DyaK2cXltVKgt78%3D 8180383
    • (1994) Blood , vol.83 , pp. 2878-2892
    • Permpikul, P.1    Rao, L.V.2    Rapaport, S.I.3
  • 11
    • 0025102933 scopus 로고
    • Immunoglobulin G fractions from patients with antiphospholipid antibodies caused fetal death in Balb/c mice: A model for autoimmune fetal loss
    • 1:STN:280:DyaK3czivVajsg%3D%3D 2197866
    • DW Branch DJ Dudley MD Mitchell, et al. 1990 Immunoglobulin G fractions from patients with antiphospholipid antibodies caused fetal death in Balb/c mice: a model for autoimmune fetal loss Am J Obstet Gynecol 163 210 216 1:STN:280:DyaK3czivVajsg%3D%3D 2197866
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 210-216
    • Branch, D.W.1    Dudley, D.J.2    Mitchell, M.D.3
  • 12
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • SS Pierangeli M Colden-Stanfield XW Liu, et al. 1999 Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo Circulation 99 1997 2002 1:CAS:528:DyaK1MXivFSrsbo%3D 10209004 (Pubitemid 29183897)
    • (1999) Circulation , vol.99 , Issue.15 , pp. 1997-2002
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, X.3    Barker, J.H.4    Anderson, G.L.5    Harris, E.N.6
  • 13
    • 0023766962 scopus 로고
    • Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells-inhibition of thrombomodulin-dependent protein C activation
    • 1:STN:280:DyaL1M%2FksVOjtA%3D%3D 2847352
    • R Cariou G Tobelem S Bellucci, et al. 1988 Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells-inhibition of thrombomodulin-dependent protein C activation Thromb Haemost 60 54 58 1:STN:280:DyaL1M%2FksVOjtA%3D%3D 2847352
    • (1988) Thromb Haemost , vol.60 , pp. 54-58
    • Cariou, R.1    Tobelem, G.2    Bellucci, S.3
  • 14
    • 0024433923 scopus 로고
    • Impaired catalytic function of activated protein C: A new in vitro manifestation of lupus anticoagulant
    • 1:STN:280:DyaK3c%2FivVOrtw%3D%3D 2508795
    • E Marciniak EH Romond 1989 Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant Blood 74 2426 2432 1:STN:280:DyaK3c%2FivVOrtw%3D%3D 2508795
    • (1989) Blood , vol.74 , pp. 2426-2432
    • Marciniak, E.1    Romond, E.H.2
  • 15
    • 0026786517 scopus 로고
    • Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells
    • 1:STN:280:DyaK3s%2FmvFSkug%3D%3D 1440490
    • M Borrell N Sala C de Castellarnau, et al. 1992 Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells Thromb Haemost 68 268 272 1:STN:280:DyaK3s%2FmvFSkug%3D%3D 1440490
    • (1992) Thromb Haemost , vol.68 , pp. 268-272
    • Borrell, M.1    Sala, N.2    De Castellarnau, C.3
  • 16
    • 0026582938 scopus 로고
    • Plasma from systemic lupus erythematosus patients with antiphospholipid antibodies promotes platelet aggregation
    • 1:STN:280:DyaK387otF2isg%3D%3D 1543693
    • G Escolar J Font JC Reverter, et al. 1992 Plasma from systemic lupus erythematosus patients with antiphospholipid antibodies promotes platelet aggregation Arterioscler Thromb 12 196 200 1:STN:280:DyaK387otF2isg%3D%3D 1543693
    • (1992) Arterioscler Thromb , vol.12 , pp. 196-200
    • Escolar, G.1    Font, J.2    Reverter, J.C.3
  • 17
    • 4444273214 scopus 로고    scopus 로고
    • Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin
    • DOI 10.1002/art.20434
    • M Vega-Ostertag EN Harris SS Pierangeli 2004 Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin Arthritis Rheum 50 2911 2919 10.1002/art.20434 1:CAS:528:DC%2BD2cXoslGgsb4%3D 15457460 (Pubitemid 39209530)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.9 , pp. 2911-2919
    • Vega-Ostertag, M.1    Harris, E.N.2    Pierangeli, S.S.3
  • 18
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies
    • 1:CAS:528:DyaK2cXlsFGntbc%3D 8027560
    • A Kornberg M Blank S Kaufman Y Shoenfeld 1994 Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies J Immunol 153 1328 1332 1:CAS:528:DyaK2cXlsFGntbc%3D 8027560
    • (1994) J Immunol , vol.153 , pp. 1328-1332
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3    Shoenfeld, Y.4
  • 19
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • 10.1172/JCI118276 1:CAS:528:DyaK28XltF2jtA%3D%3D 7593607
    • R Simantov JM LaSala SK Lo, et al. 1995 Activation of cultured vascular endothelial cells by antiphospholipid antibodies J Clin Invest 96 2211 2219 10.1172/JCI118276 1:CAS:528:DyaK28XltF2jtA%3D%3D 7593607
    • (1995) J Clin Invest , vol.96 , pp. 2211-2219
    • Simantov, R.1    Lasala, J.M.2    Lo, S.K.3
  • 20
    • 0031886679 scopus 로고    scopus 로고
    • The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
    • 1:CAS:528:DyaK1cXhtVeju7Y%3D 9493575
    • O Amengual T Atsumi MA Khamashta GR Hughes 1998 The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome Thromb Haemost 79 276 281 1:CAS:528:DyaK1cXhtVeju7Y%3D 9493575
    • (1998) Thromb Haemost , vol.79 , pp. 276-281
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3    Hughes, G.R.4
  • 21
    • 18644361988 scopus 로고    scopus 로고
    • Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
    • DOI 10.1002/art.21009
    • M Vega-Ostertag K Casper R Swerlick, et al. 2005 Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies Arthritis Rheum 52 1545 1554 10.1002/art.21009 1:CAS:528: DC%2BD2MXkvFCisrg%3D 15880836 (Pubitemid 40663946)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.5 , pp. 1545-1554
    • Vega-Ostertag, M.1    Casper, K.2    Swerlick, R.3    Ferrara, D.4    Harris, E.N.5    Pierangeli, S.S.6
  • 23
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • DOI 10.1002/art.21157
    • SS Pierangeli G Girardi M Vega-Ostertag, et al. 2005 Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia Arthritis Rheum 52 2120 2124 10.1002/art.21157 1:CAS:528:DC%2BD2MXnsl2gt7w%3D 15986360 (Pubitemid 40994335)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.7 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3    Liu, X.4    Espinola, R.G.5    Salmon, J.6
  • 24
    • 0242585716 scopus 로고    scopus 로고
    • Blood coagulation
    • 10.1016/S0140-6736(00)02225-X 1:CAS:528:DC%2BD3cXjs1Glu7s%3D 10821379
    • B Dahlback 2000 Blood coagulation Lancet 355 1627 1632 10.1016/S0140-6736(00)02225-X 1:CAS:528:DC%2BD3cXjs1Glu7s%3D 10821379
    • (2000) Lancet , vol.355 , pp. 1627-1632
    • Dahlback, B.1
  • 25
    • 0030729944 scopus 로고    scopus 로고
    • Congenital thrombophilia
    • DOI 10.1016/S0950-3552(97)80020-X
    • ID Walker 1997 Congenital thrombophilia Baillieres Clin Obstet Gynaecol 11 431 445 10.1016/S0950-3552(97)80020-X 1:STN:280:DyaK1c7ltVSnsA%3D%3D 9488784 (Pubitemid 27470550)
    • (1997) Bailliere's Clinical Obstetrics and Gynaecology , vol.11 , Issue.3 , pp. 431-445
    • Walker, I.D.1
  • 26
    • 0031801933 scopus 로고    scopus 로고
    • Syndromes of thrombosis and hypercoagulability: Congenital and acquired causes of thrombosis
    • DOI 10.1016/S0025-7125(05)70004-3
    • RL Bick H Kaplan 1998 Syndromes of thrombosis and hypercoagulability: congenital and acquired causes of thrombosis Med Clin North Am 82 409 458 10.1016/S0025-7125(05)70004-3 1:STN:280:DyaK1czhtVOnsw%3D%3D 9646773 (Pubitemid 28244018)
    • (1998) Medical Clinics of North America , vol.82 , Issue.3 , pp. 409-458
    • Bick, R.L.1    Kaplan, H.2
  • 27
    • 0029959119 scopus 로고    scopus 로고
    • Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid
    • 1:CAS:528:DyaK28XntlKgur0%3D 8943852
    • LV Rao AD Hoang SI Rapaport 1996 Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid Blood 88 4173 4182 1:CAS:528:DyaK28XntlKgur0%3D 8943852
    • (1996) Blood , vol.88 , pp. 4173-4182
    • Rao, L.V.1    Hoang, A.D.2    Rapaport, S.I.3
  • 28
    • 0033495741 scopus 로고    scopus 로고
    • An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times
    • DOI 10.1002/1529-0131(199910)42:10<2132::AID-ANR13>3.0.CO;2-B
    • Y Zhao R Rumold M Zhu, et al. 1999 An IgG anti-prothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times Arthritis Rheum 42 2132 2138 10.1002/1529-0131(199910)42: 10<2132::AID-ANR13>3.0.CO;2-B 1:CAS:528:DyaK1MXmvV2ks7o%3D 10524684 (Pubitemid 30263596)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.10 , pp. 2132-2138
    • Zhao, Y.1    Rumold, R.2    Zhu, M.3    Zhou, D.4    Ahmed, A.E.5    Le, D.T.6    Hahn, B.H.7    Woods Jr., V.L.8    Chen, P.P.9
  • 29
    • 33748748970 scopus 로고    scopus 로고
    • A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells
    • DOI 10.1111/j.1365-2141.2006.06283.x
    • M Vega-Ostertag X Liu H Kwan-Ki, et al. 2006 A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells Br J Haematol 135 214 219 10.1111/j.1365-2141.2006.06283.x 1:CAS:528:DC%2BD28Xht1Wntb%2FK 16965389 (Pubitemid 44401619)
    • (2006) British Journal of Haematology , vol.135 , Issue.2 , pp. 214-219
    • Vega-Ostertag, M.1    Liu, X.2    Kwan-Ki, H.3    Chen, P.4    Pierangeli, S.5
  • 30
    • 0033506297 scopus 로고    scopus 로고
    • Endothelial Cell function and thrombosis
    • 1:STN:280:DC%2BD3czhtFSqsg%3D%3D 10856973
    • JD Pearson 1999 Endothelial Cell function and thrombosis Baillieres Best Pract Res Clin Haematol 12 329 341 1:STN:280:DC%2BD3czhtFSqsg%3D%3D 10856973
    • (1999) Baillieres Best Pract Res Clin Haematol , vol.12 , pp. 329-341
    • Pearson, J.D.1
  • 31
    • 0035893021 scopus 로고    scopus 로고
    • Identification of anti-thrombin antibodies in the antiphospholipid syndrome that interfere with the inactivation of thrombin by antithrombin
    • 1:CAS:528:DC%2BD3MXptFGhsrg%3D 11739542
    • KK Hwang JM Grossman S Visvanathan, et al. 2001 Identification of anti-thrombin antibodies in the antiphospholipid syndrome that interfere with the inactivation of thrombin by antithrombin J Immunol 167 7192 7198 1:CAS:528:DC%2BD3MXptFGhsrg%3D 11739542
    • (2001) J Immunol , vol.167 , pp. 7192-7198
    • Hwang, K.K.1    Grossman, J.M.2    Visvanathan, S.3
  • 32
    • 0033832202 scopus 로고    scopus 로고
    • Functional analyses of patient-derived IgG monoclonal anticardiolipin antibodies using in vivo thrombosis and in vivo microcirculation models
    • 1:CAS:528:DC%2BD3MXjtVOksLw%3D 11019960
    • SS Pierangeli X Liu R Espinola, et al. 2000 Functional analyses of patient-derived IgG monoclonal anticardiolipin antibodies using in vivo thrombosis and in vivo microcirculation models Thromb Haemost 84 388 395 1:CAS:528:DC%2BD3MXjtVOksLw%3D 11019960
    • (2000) Thromb Haemost , vol.84 , pp. 388-395
    • Pierangeli, S.S.1    Liu, X.2    Espinola, R.3
  • 33
    • 0037975660 scopus 로고    scopus 로고
    • A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C
    • DOI 10.1002/art.10983
    • KK Hwang CD Yang W Yan, et al. 2003 A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C Arthritis Rheum 48 1622 1630 10.1002/art.10983 1:CAS:528:DC%2BD3sXltlSgu74%3D 12794830 (Pubitemid 36682370)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.6 , pp. 1622-1630
    • Hwang, K.-K.1    Yang, C.-D.2    Yan, W.3    Grossman, J.M.4    Hahn, B.H.5    Chen, P.P.6
  • 34
    • 2142704424 scopus 로고    scopus 로고
    • Identification of anti-plasmin antibodies in the antiphospholipid syndrome that inhibit degradation of fibrin
    • 1:CAS:528:DC%2BD2cXjt1CkurY%3D 15100323
    • CD Yang KK Hwang W Yan, et al. 2004 Identification of anti-plasmin antibodies in the antiphospholipid syndrome that inhibit degradation of fibrin J Immunol 172 5765 5773 1:CAS:528:DC%2BD2cXjt1CkurY%3D 15100323
    • (2004) J Immunol , vol.172 , pp. 5765-5773
    • Yang, C.D.1    Hwang, K.K.2    Yan, W.3
  • 35
    • 0036125784 scopus 로고    scopus 로고
    • Immunoglobulin g from patients with antiphospholipid syndrome impairs the fibrin dissolution with plasmin
    • 1:CAS:528:DC%2BD38XislGjsrY%3D 11916083
    • K Kolev J Gombas B Varadi, et al. 2002 Immunoglobulin g from patients with antiphospholipid syndrome impairs the fibrin dissolution with plasmin Thromb Haemost 87 502 508 1:CAS:528:DC%2BD38XislGjsrY%3D 11916083
    • (2002) Thromb Haemost , vol.87 , pp. 502-508
    • Kolev, K.1    Gombas, J.2    Varadi, B.3
  • 36
    • 0030589375 scopus 로고    scopus 로고
    • The anti-b2-glycoprotein i activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native b2-glycoprotein i and preserved during species' evolution
    • 1:CAS:528:DyaK28XnsFCnu7Y%3D 8955227
    • A Tincani L Spatola E Prati, et al. 1996 The anti-b2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native b2-glycoprotein I and preserved during species' evolution J Immunol 157 5732 5738 1:CAS:528:DyaK28XnsFCnu7Y%3D 8955227
    • (1996) J Immunol , vol.157 , pp. 5732-5738
    • Tincani, A.1    Spatola, L.2    Prati, E.3
  • 37
    • 0032892020 scopus 로고    scopus 로고
    • 2GP1 antibodies from two patients with antiphospholipid syndrome reveals three species of antibodies
    • DOI 10.1111/j.1365-2141.1999.01292.x
    • M Zhu T Olee DT Le, et al. 1999 Characterization of IgG monoclonal anti-cardiolipin/antib2GP1 antibodies from two patients with the anti-phospholipid syndrome reveals three species of antibodies Br J Haematol 105 102 109 10.1111/j.1365-2141.1999.01292.x 1:STN:280:DyaK1M3ltVGisw%3D%3D 10233371 (Pubitemid 29197150)
    • (1999) British Journal of Haematology , vol.105 , Issue.1 , pp. 102-109
    • Zhu, M.1    Olee, T.2    Dzung, T.L.E.3    Roubey, R.A.S.4    Hahn, D.H.5    Woods Jr., V.L.6    Chen, P.P.7
  • 39
    • 1542373659 scopus 로고    scopus 로고
    • Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: Evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients
    • DOI 10.1182/blood-2003-07-2422
    • M Cugno M Cabibbe M Galli, et al. 2004 Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients Blood 103 2121 2126 10.1182/blood-2003-07-2422 1:CAS:528: DC%2BD2cXitlequro%3D 14630788 (Pubitemid 38326228)
    • (2004) Blood , vol.103 , Issue.6 , pp. 2121-2126
    • Cugno, M.1    Cabibbe, M.2    Galli, M.3    Meroni, P.L.4    Caccia, S.5    Russo, R.6    Bottasso, B.7    Mannucci, P.M.8
  • 40
    • 34248523994 scopus 로고    scopus 로고
    • 2-glycoprotein I and the homologous catalytic domains of several serine proteases
    • DOI 10.1002/art.22522
    • WS Lin PC Chen CD Yang, et al. 2007 Some antiphospholipid antibodies recognize conformational epitopes shared by beta(2)-glycoprotein I and the homologous catalytic domains of several serine proteases Arthritis Rheum 56 1638 1647 10.1002/art.22522 1:CAS:528:DC%2BD2sXmsFartLY%3D 17469158 This paper showed that both patient-derived IgG monoclonal anti-β2GPI antibodies bind to three serine proteases in hemostasis and that a patient-derived IgG mAb against protein C (P1) reacted with β2GPI. Moreover, P1 binding to β2GPI and thrombin was crossinhibited by both antigens, indicating that the P1 aPL recognizes shared epitope(s) on β2GPI and thrombin, which represents the homologous enzymatic domains of several targeted serine protease (Pubitemid 46764093)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.5 , pp. 1638-1647
    • Lin, W.-S.1    Chen, P.-C.2    Yang, C.-B.3    Cho, E.4    Hahn, B.H.5    Grossman, J.6    Hwang, K.-K.7    Chen, P.P.8
  • 41
    • 34247153549 scopus 로고    scopus 로고
    • Some plasmin-induced antibodies bind to cardiolipin, display lupus anticoagulant activity and induce fetal loss in mice
    • 1:CAS:528:DC%2BD2sXjslWjtb0%3D 17404320 This paper showed that plasmin immunization in mice induced pathogenic aPL
    • XX Chen YY Gu SJ Li, et al. 2007 Some plasmin-induced antibodies bind to cardiolipin, display lupus anticoagulant activity and induce fetal loss in mice J Immunol 178 5351 5356 1:CAS:528:DC%2BD2sXjslWjtb0%3D 17404320 This paper showed that plasmin immunization in mice induced pathogenic aPL
    • (2007) J Immunol , vol.178 , pp. 5351-5356
    • Chen, X.X.1    Gu, Y.Y.2    Li, S.J.3
  • 42
    • 0018135382 scopus 로고
    • A sensitive test demonstrating lupus anticoagulant and its behavioural patterns
    • 10.1111/j.1365-2141.1978.tb03648.x 1:STN:280:DyaE1M%2FktF2qsQ%3D%3D 568479
    • T Exner KA Rickard H Kronenberg 1978 A sensitive test demonstrating lupus anticoagulant and its behavioural patterns Br J Haematol 40 143 151 10.1111/j.1365-2141.1978.tb03648.x 1:STN:280:DyaE1M%2FktF2qsQ%3D%3D 568479
    • (1978) Br J Haematol , vol.40 , pp. 143-151
    • Exner, T.1    Rickard, K.A.2    Kronenberg, H.3
  • 43
    • 0033834033 scopus 로고    scopus 로고
    • Epidemiology of the antiphospholipid antibody syndrome
    • DOI 10.1006/jaut.2000.0409
    • M Petri 2000 Epidemiology of the antiphospholipid antibody syndrome J Autoimmun 15 145 151 10.1006/jaut.2000.0409 1:STN:280:DC%2BD3M7nvVWjsg%3D%3D 10968901 (Pubitemid 30707584)
    • (2000) Journal of Autoimmunity , vol.15 , Issue.2 , pp. 145-151
    • Petri, M.1
  • 44
    • 67649784889 scopus 로고    scopus 로고
    • How to manage patients with systemic lupus erythematosus who are also antiphospholipid antibody positive
    • 10.1016/j.berh.2009.01.009 19591782
    • I Giles A Rahman 2009 How to manage patients with systemic lupus erythematosus who are also antiphospholipid antibody positive Best Pract Res Clin Rheumatol 23 525 537 10.1016/j.berh.2009.01.009 19591782
    • (2009) Best Pract Res Clin Rheumatol , vol.23 , pp. 525-537
    • Giles, I.1    Rahman, A.2
  • 45
    • 33746210258 scopus 로고    scopus 로고
    • Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens
    • 1:CAS:528:DC%2BD28XmvFCmu7s%3D 16849482
    • I Giles N Lambrianides N Pattni, et al. 2006 Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens J Immunol 177 1729 1736 1:CAS:528:DC%2BD28XmvFCmu7s%3D 16849482
    • (2006) J Immunol , vol.177 , pp. 1729-1736
    • Giles, I.1    Lambrianides, N.2    Pattni, N.3
  • 46
    • 65249133581 scopus 로고    scopus 로고
    • Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions
    • 10.4049/jimmunol.0804241 1:CAS:528:DC%2BD1MXjvFOjurY%3D 19342662 This paper shows that the reactivity of a panel of closely related monoclonal aPL with thrombin, most closely predicts their ability to promote thrombosis and activate endothelial cells in a murine model of thrombosis and microcirculation
    • I Giles C Pericleous X Liu, et al. 2009 Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions J Immunol 182 4836 4843 10.4049/jimmunol.0804241 1:CAS:528:DC%2BD1MXjvFOjurY%3D 19342662 This paper shows that the reactivity of a panel of closely related monoclonal aPL with thrombin, most closely predicts their ability to promote thrombosis and activate endothelial cells in a murine model of thrombosis and microcirculation
    • (2009) J Immunol , vol.182 , pp. 4836-4843
    • Giles, I.1    Pericleous, C.2    Liu, X.3
  • 47
    • 14044254724 scopus 로고    scopus 로고
    • Elevated clotting factor levels and venous thrombosis
    • DOI 10.1159/000083835
    • RM Bertina 2003 Elevated clotting factor levels and venous thrombosis Pathophysiol Haemost Thromb 33 395 400 10.1159/000083835 15692250 (Pubitemid 40278714)
    • (2003) Pathophysiology of Haemostasis and Thrombosis , vol.33 , Issue.5-6 , pp. 395-400
    • Bertina, R.M.1
  • 48
    • 0036881507 scopus 로고    scopus 로고
    • Antithrombin deficiency: Issues in laboratory diagnosis
    • 1:CAS:528:DC%2BD3sXhtFGgtr4%3D 12421140
    • K Kottke-Marchant A Duncan 2002 Antithrombin deficiency: issues in laboratory diagnosis Arch Pathol Lab Med 126 1326 1336 1:CAS:528: DC%2BD3sXhtFGgtr4%3D 12421140
    • (2002) Arch Pathol Lab Med , vol.126 , pp. 1326-1336
    • Kottke-Marchant, K.1    Duncan, A.2
  • 49
    • 0019957643 scopus 로고
    • Computer-generated models of blood coagulation factor Xa, factor IXa, and thrombin based upon structural homology with other serine proteases
    • 1:CAS:528:DyaL38XhslKqtrk%3D 7037788
    • B Furie DH Bing RJ Feldmann, et al. 1982 Computer-generated models of blood coagulation factor Xa, factor IXa, and thrombin based upon structural homology with other serine proteases J Biol Chem 257 3875 3882 1:CAS:528:DyaL38XhslKqtrk%3D 7037788
    • (1982) J Biol Chem , vol.257 , pp. 3875-3882
    • Furie, B.1    Bing, D.H.2    Feldmann, R.J.3
  • 50
    • 63149169674 scopus 로고    scopus 로고
    • Novel autoantibodies against the activated coagulation factor IX (FIXa) in the antiphospholipid syndrome that interpose the FIXa regulation by antithrombin
    • 1:CAS:528:DC%2BD1MXnsVCjtA%3D%3D 19155517 This paper demonstrated that some aPL bound to FIXa and hindered inactivation of FIXa by antithrombin and that such FIXa-reactive aPL occurred in 11 of 38 (28.9%) patients with APS tested
    • YH Yang D Chien M Wu, et al. 2009 Novel autoantibodies against the activated coagulation factor IX (FIXa) in the antiphospholipid syndrome that interpose the FIXa regulation by antithrombin J Immunol 182 1674 1680 1:CAS:528:DC%2BD1MXnsVCjtA%3D%3D 19155517 This paper demonstrated that some aPL bound to FIXa and hindered inactivation of FIXa by antithrombin and that such FIXa-reactive aPL occurred in 11 of 38 (28.9%) patients with APS tested
    • (2009) J Immunol , vol.182 , pp. 1674-1680
    • Yang, Y.H.1    Chien, D.2    Wu, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.