Mast cell and T cell communication; amplification and control of adaptive immunity

Immunology Letters

Volumn 128, Issue 2, 2010, Pages 98-104

  Hershko, Alon Y ^a   Rivera, Juan ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

Communication; Mast cells; Molecular interaction; T cells; T effectors; Tregs

Indexed keywords

B7 ANTIGEN; CD134 ANTIGEN; CD137 ANTIGEN; CD30 LIGAND; CD86 ANTIGEN; FAS ANTIGEN; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 9; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OX40 LIGAND; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTING CELL; AUTOIMMUNITY; CELL ACTIVITY; CELL COMMUNICATION; CELL EXPANSION; CELL FUNCTION; CELL INTERACTION; CYTOKINE PRODUCTION; CYTOLOGY; DENDRITIC CELL; DISEASE COURSE; DISEASE SEVERITY; EFFECTOR CELL; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFLAMMATORY CELL; MAST CELL; MAST CELL DEGRANULATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SIGNAL TRANSDUCTION; SUPPRESSOR CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL;

ADAPTIVE IMMUNITY; ANIMALS; CELL COMMUNICATION; CELL LINE; CELLS, CULTURED; HUMANS; MAST CELLS; MICE; T-LYMPHOCYTES;

EID: 77249093469     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.10.013     Document Type: Review

References (85)

1. Beaven M.A. Our perception of the mast cell from Paul Ehrlich to now. Eur J Immunol 2009, 39:11-25.
2. Prausnitz C. The passive transfer of allergy. Int Arch Allergy Appl Immunol 1955, 6:260-269.
3. Riley J.F., West G.B. Tissue mast cells: studies with a histamine-liberator of low toxicity (compound 48/80). J Pathol Bacteriol 1955, 69:269-282.
4. Ishizaka K., Ishizaka T. Identification of γ-E-antibodies as a carrier of reaginic activity. J Immunol 1967, 99:1187-1198.
5. Blank U., Ra C., Miller L., White K., Metzger H., Kinet J.P. Complete structure and expression in transfected cells of high affinity IgE receptor. Nature 1989, 337:187-189.
6. Metzger H., Blank U., Kinet J.-P., Kochan J., Ra C., Rivera J. Emerging picture of the receptor with high affinity for IgE. Int Arch Allergy Appl Immunol 1989, 88:14-17.
7. Ishizaka T., White J.R., Saito H. Activation of basophils and mast cells for mediator release. Int Arch AllergyAppl Immunol 1987, 82:327-332.
8. Askenase P.W. Immune inflammatory responses to parasites: the role of basophils, mast cells and vasoactive amines. Am J Trop Med Hyg 1977, 26:96-103.
9. Burd P.R., Rogers H.W., Sundararajan J., Wilson S.D., Dvorak A.M., Galli S.J., et al. Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines. J Exp Med 1989, 170:245-257.
10. Plaut M., Pierce J.H., Watson C.J., Hanley-Hyde J., Nordan R.P., Paul W.E. Mast cell lines produce lymphokines in response to cross-linkage of Fce{open}RI or to calcium ionophores. Nature 1989, 339:64-67.
11. Malaviya R., Ikeda T., Ross E., Abraham S.N. Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α. Nature 1996, 381:77-80.
12. Leal-Berumen I., Conlon P., Marshall J.S. IL-6 production by rat peritoneal mast cells is not necessarily preceded by histamine release and can be induced by bacterial lipopolysaccharide. J Immunol 1994, 152:5468-5476.
13. Marshall J.S. Mast-cell responses to pathogens. Nat Rev Immunol 2004, 4:787-799.
14. Mekori Y.A., Metcalfe D.D. Mast cells in innate immunity. Immunol Rev 2000, 173:131-140.
15. Okumura S., Kashiwakura J., Tomita H., Matsumoto K., Nakajima T., Saito H., et al. Identification of specific gene expression profiles in human mast cells mediated by Toll-like receptor 4 and Fce{open}RI. Blood 2003, 102:2547-2554.
16. Galli S.J., Kalesnikoff J., Grimbaldeston M.A., Piliponsky A.M., Williams C.M., Tsai M. Mast cells as " tunable" effector and immunoregulatory cells: recent advances. Annu Rev Immunol 2005, 23:749-786.
17. Rivera J. Snake bites and bee stings: the mast cell strikes back. Nat Med 2006, 12:999-1000.
18. Metz M., Piliponsky A.M., Chen C.C., Lammel V., Abrink M., Pejler G., et al. Mast cells can enhance resistance to snake and honeybee venoms. Science 2006, 313:526-530.
19. Galli S.J., Nakae S., Tsai M. Mast cells in the development of adaptive immune responses. Nat Immunol 2005, 6:135-142.
20. Sayed B.A., Brown M.A. Mast cells as modulators of T-cell responses. Immunol Rev 2007, 217:53-64.
21. Nakae S., Suto H., Iikura M., Kakurai M., Sedgwick J.D., Tsai M., et al. Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF. J Immunol 2006, 176:2238-2248.
22. Rao K.N., Brown M.A. Mast cells: multifaceted immune cells with diverse roles in health and disease. Ann N Y Acad Sci 2008, 1143:83-104.
23. Kolsch E. The genetic control of T cell-mediated immunity against the DBA/2 mastocytoma P-815. II. Low responsiveness in T cell-mediated cytotoxicity accompanied by the inability to produce antibodies in a secondary response. Eur J Immunol 1975, 5:527-532.
24. Balk S.P., Mescher M.F. Specific reversal of cytolytic T lymphocyte-target cell interaction. J Supramol Struct Cell Biochem 1981, 16:43-52.
25. Balk S.P., Walker J., Mescher M.F. Kinetics of cytolytic T lymphocyte binding to target cells in suspension. J Immunol 1981, 126:2177-2183.
26. Giulling E.V., Nikol'skii I.S., Diugovskaia L.A., Chernenko O.D., Ovsienko V.V. Contact interaction of mast cells and lymphocytes during ontogenetic antigen-induced differentiation and malignant transformation of lymphoid cells. Biull Eksp Biol Med 1980, 89:584-585.
27. Fox C.C., Jewell S.D., Whitacre C.C. Rat peritoneal mast cells present antigen to a PPD-specific T cell line. Cell Immunol 1994, 158:253-264.
28. Inamura N., Mekori Y.A., Bhattacharyya S.P., Bianchine P.J., Metcalfe D.D. Induction and enhancement of Fce{open}RI-dependent mast cell degranulation following coculture with activated T cells: dependency on ICAM-1- and leukocyte function-associated antigen (LFA)-1-mediated heterotypic aggregation. J Immunol 1998, 160:4026-4033.
29. Orr E.L. Presence and distribution of nervous system-associated mast cells that may modulate experimental autoimmune encephalomyelitis. Ann N Y Acad Sci 1988, 540:723-726.
30. Secor V.H., Secor W.E., Gutekunst C.A., Brown M.A. Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J Exp Med 2000, 191:813-822.
31. Gregory G.D., Robbie-Ryan M., Secor V.H., Sabatino J.J., Brown M.A. Mast cells are required for optimal autoreactive T cell responses in a murine model of multiple sclerosis. Eur J Immunol 2005, 35:3478-3486.
32. Tanzola M.B., Robbie-Ryan M., Gutekunst C.A., Brown M.A. Mast cells exert effects outside the central nervous system to influence experimental allergic encephalomyelitis disease course. J Immunol 2003, 171:4385-4391.
33. + T lymphocytes. Eur J Immunol 1996, 26:2517-2528.
34. Kambayashi T., Allenspach E.J., Chang J.T., Zou T., Shoag J.E., Reiner S.L., et al. Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation. J Immunol 2009, 182:4686-4695.
35. Gaudenzio N., Espagnole N., Mars L.T., Liblau R., Valitutti S., Espinosa E. Cell-cell cooperation at the T helper cell/mast cell immunological synapse. Blood 2009.
36. Nakano N., Nishiyama C., Yagita H., Koyanagi A., Akiba H., Chiba S., et al. Notch signaling confers antigen-presenting cell functions on mast cells. J Allergy Clin Immunol 2009, 123:74-81. e71.
37. + T cell effector functions. Immunity 2009, 31:665-676.
38. + regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction. Immunity 2008, 29:771-781.
39. Kashiwakura J., Yokoi H., Saito H., Okayama Y. T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells. J Immunol 2004, 173:5247-5257.
40. Piconese S., Gri G., Tripodo C., Musio S., Gorzanelli A., Frossi B., et al. Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation. Blood 2009, 114:2639-2648.
41. Nakae S., Suto H., Kakurai M., Sedgwick J.D., Tsai M., Galli S.J. Mast cells enhance T cell activation: importance of mast cell-derived TNF. Proc Natl Acad Sci USA 2005, 102:6467-6472.
42. Khan M.M., Strober S., Melmon K.L. Regulatory effects of mast cells on lymphoid cells: the role of histamine type 1 receptors in the interaction between mast cells, helper T cells and natural suppressor cells. Cell Immunol 1986, 103:41-53.
43. Huang B., Lei Z., Zhang G.M., Li D., Song C., Li B., et al. SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood 2008, 112:1269-1279.
44. Fujita T., Kambe N., Uchiyama T., Hori T. Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-α production and OX40 ligand expression while increasing IL-10 production. J Clin Immunol 2006, 26:512-518.
45. Gounaris E., Blatner N.R., Dennis K., Magnusson F., Gurish M.F., Strom T.B., et al. T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis. Cancer Res 2009, 69:5490-5497.
46. Gounaris E., Erdman S.E., Restaino C., Gurish M.F., Friend D.S., Gounari F., et al. Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci USA 2007, 104:19977-19982.
47. + T regulatory cell suppressor function via histamine H1 receptor interaction. J Immunol 2009, 183:3014-3022.
48. Sedor J.R., Abboud H.E. Actions and metabolism of histamine in glomeruli and tubules of the human kidney. Kidney Int 1984, 26:144-152.
49. Hershko A.Y., Dranitzki Z., Ulmanski R., Levi-Schaffer F., Naparstek Y. Constitutive hyperhistaminaemia: a possible mechanism for recurrent anaphylaxis. Scand J Clin Lab Invest 2001, 61:449-452.
50. Maintz L., Novak N. Histamine and histamine intolerance. Am J Clin Nutr 2007, 85:1185-1196.
51. Morrow J.D., Margolies G.R., Rowland J., Roberts L.J. Evidence that histamine is the causative toxin of scombroid-fish poisoning. N Engl J Med 1991, 324:716-720.
52. Jin H., Kang Y., Zhao L., Xiao C., Hu Y., She R., et al. Induction of adaptive T regulatory cells that suppress the allergic response by coimmunization of DNA and protein vaccines. J Immunol 2008, 180:5360-5372.
53. Nordlund J.J., Askenase P.W. The effect of histamine, antihistamines, and a mast cell stabilizer on the growth of cloudman melanoma cells in DBA/2 mice. J Invest Dermatol 1983, 81:28-31.
54. Wang J., Su B., Ding Z., Du X., Wang B. Cimetidine enhances immune response of HBV DNA vaccination via impairment of the regulatory function of regulatory T cells. Biochem Biophys Res Commun 2008, 372:491-496.
55. Lohr J., Knoechel B., Abbas A.K. Regulatory T cells in the periphery. Immunol Rev 2006, 212:149-162.
56. Kennedy Norton S., Barnstein B., Brenzovich J., Bailey D.P., Kashyap M., Speiran K., et al. IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo. J Immunol 2008, 180:2848-2854.
57. Norozian F., Kashyap M., Ramirez C.D., Patel N., Kepley C.L., Barnstein B.O., et al. TGFβ1 induces mast cell apoptosis. Exp Hematol 2006, 34:579-587.
58. Kashyap M., Thornton A.M., Norton S.K., Barnstein B., Macey M., Brenzovich J., et al. Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling. J Immunol 2008, 180:2039-2043.
59. Holgate S.T., Lewis R.A., Austen K.F. Role of adenylate cyclase in immunologic release of mediators from rat mast cells: agonist and antagonist effects of purine- and ribose-modified adenosine analogs. Proc Natl Acad Sci USA 1980, 77:6800-6804.
60. 2+ blockers, calmodulin inhibitors and cAMP. Immunopharmacology 1989, 18:177-186.
61. Winslow C.M., Lewis R.A., Austen K.F. Mast cell mediator release as a function of cyclic AMP-dependent protein kinase activation. J Exp Med 1981, 154:1125-1133.
62. Ohshima Y., Tanaka Y., Tozawa H., Takahashi Y., Maliszewski C., Delespesse G. Expression and function of OX40 ligand on human dendritic cells. J Immunol 1997, 159:3838-3848.
63. + regulatory T cells increases bacterial clearance and improves survival in polymicrobial sepsis. J Immunol 2005, 174:7141-7146.
64. Huang C., De Sanctis G.T., O'Brien P.J., Mizgerd J.P., Friend D.S., Drazen J.M., et al. Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung. J Biol Chem 2001, 276:26276-26284.
65. Huang C., Friend D.S., Qiu W.T., Wong G.W., Morales G., Hunt J., et al. Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6. J Immunol 1998, 160:1910-1919.
66. Thakurdas S.M., Melicoff E., Sansores-Garcia L., Moreira D.C., Petrova Y., Stevens R.L., et al. The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. J Biol Chem 2007, 282:20809-20815.
67. Ju M.J., Qiu S.J., Gao Q., Fan J., Cai M.Y., Li Y.W., et al. Combination of peritumoral mast cells and T-regulatory cells predicts prognosis of hepatocellular carcinoma. Cancer Sci 2009, 100:1267-1274.
68. Wasiuk A., de Vries V.C., Hartmann K., Roers A., Noelle R.J. Mast cells as regulators of adaptive immunity to tumours. Clin Exp Immunol 2009, 155:140-146.
69. Grimbaldeston M.A., Nakae S., Kalesnikoff J., Tsai M., Galli S.J. Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nat Immunol 2007, 8:1095-1104.
70. Hart P.H., Grimbaldeston M.A., Swift G.J., Jaksic A., Noonan F.P., Finlay-Jones J.J. Dermal mast cells determine susceptibility to ultraviolet B-induced systemic suppression of contact hypersensitivity responses in mice. J Exp Med 1998, 187:2045-2053.
71. Depinay N., Hacini F., Beghdadi W., Peronet R., Mecheri S. Mast cell-dependent down-regulation of antigen-specific immune responses by mosquito bites. J Immunol 2006, 176:4141-4146.
72. Lu L.F., Lind E.F., Gondek D.C., Bennett K.A., Gleeson M.W., Pino-Lagos K., et al. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 2006, 442:997-1002.
73. Veldhoen M., Uyttenhove C., van Snick J., Helmby H., Westendorf A., Buer J., et al. Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008, 9:1341-1346.
74. de Vries V.C., Wasiuk A., Bennett K.A., Benson M.J., Elgueta R., Waldschmidt T.J., et al. Mast cell degranulation breaks peripheral tolerance. Am J Transplant 2009, 9:2270-2280.
75. v mice and their increase by bone marrow transplantation. Blood 1978, 52:447-452.
76. sh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy. Am J Pathol 2008, 173:1693-1701.
77. -sh) sash mice. Clin Exp Allergy 2005, 35:82-88.
78. -sh mice as a model for investigating mast cell biology in vivo. Am J Pathol 2005, 167:835-848.
79. Pawankar R., Ra C. Heterogeneity of mast cells and T cells in the nasal mucosa. J Allergy Clin Immunol 1996, 98:S248-S262.
80. Goyal R., Bulua A.C., Nikolov N.P., Schwartzberg P.L., Siegel R.M. Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders. Curr Opin Rheumatol 2009, 21:78-84.
81. Fietta P. Life-or-death fate in the adaptive immune system. Riv Biol 2007, 100:267-283.
82. Candotti F., Oakes S.A., Johnston J.A., Notarangelo L.D., O'Shea J.J., Blaese R.M. In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction. J Exp Med 1996, 183:2687-2692.
83. Shelburne C.P., McCoy M.E., Piekorz R., Sexl V., Roh K.H., Jacobs-Helber S.M., et al. Stat5 expression is critical for mast cell development and survival. Blood 2003, 102:1290-1297.
84. Zhu Y., Herlaar E., Masuda E.S., Burleson G.R., Nelson A.J., Grossbard E.B., et al. Immunotoxicity assessment for the novel Spleen tyrosine kinase inhibitor R406. Toxicol Appl Pharmacol 2007, 221:268-277.
85. Braselmann S., Taylor V., Zhao H., Wang S., Sylvain C., Baluom M., et al. R406, an orally available spleen tyrosine kinase inhibitor blocks Fc receptor signaling and reduces immune complex-mediated inflammation. J Pharmacol Exp Ther 2006, 319:998-1008.