Insights into the roles of non-muscle myosin IIA in human keratinocyte migration

Cellular and Molecular Bioengineering

Volumn 2, Issue 4, 2009, Pages 486-494

  Sarkar, Saheli ^a   Egelhoff, Thomas ^c   Baskaran, Harihara ^a,b  

^a Case Western Reserve University   (United States)

^b Case Western Reserve University   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

F actin; Lamellar extension; Microfabrication; Myosin light chain kinase; Myosin regulatory light chain phosphorylation; Rho kinase; Soft lithography

Indexed keywords

1 (5 IODO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BLEBBISTATIN; MYOSIN IIA; MYOSIN LIGHT CHAIN KINASE; RHO KINASE;

ASSAY; CELL MEMBRANE; CELL MIGRATION; CELL SIZE; CELL SPREADING; CELL STRUCTURE; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTROSPECTION; KERATINOCYTE; MOTOR ACTIVITY; NEWBORN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 77149175425     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-009-0094-2     Document Type: Conference Paper

References (27)

1. M Amano M Ito K Kimura Y Fukata K Chihara T Nakano Y Matsuura K Kaibuchi K Kaibuchi K Kaibuchi K Kaibuchi 1996 Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase) J. Biol. Chem. 271 34 20246 20249 10.1074/jbc.271.34.20246 (Pubitemid 26281788)
2. BA Babbin S Koch M Bachar MA Conti CA Parkos RS Adelstein A Nusrat AI Ivanov 2009 Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion Am. J. Pathol. 174 2 436 448 10.2353/ajpath.2009.080171
3. V Betapudi LS Licate TT Egelhoff 2006 Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration Cancer Res. 66 9 4725 4733 10.1158/0008-5472.CAN-05-4236
4. MA Conti RS Adelstein 2008 Nonmuscle myosin II moves in new directions J. Cell Sci. 121 Pt 1 11 18 10.1242/jcs.007112 (Pubitemid 351265698)
5. MS Duxbury SW Ashley EE Whang 2004 Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor Biochem. Biophys. Res. Commun. 313 4 992 997 10.1016/j.bbrc.2003.12. 031 (Pubitemid 38050090)
6. RL Eckert 1989 Structure, function, and differentiation of the keratinocyte Physiol. Rev. 69 4 1316 1346
7. S Even-Ram AD Doyle MA Conti K Matsumoto RS Adelstein KM Yamada 2007 Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk Nat. Cell Biol. 9 3 299 309 10.1038/ncb1540 (Pubitemid 46344609)
8. PJ Gallagher BP Herring SA Griffin JT Stull 1991 Molecular characterization of a mammalian smooth muscle myosin light chain kinase J. Biol. Chem. 266 35 23936 23944
9. E Golomb X Ma SS Jana YA Preston S Kawamoto NG Shoham E Goldin MA Conti JR Sellers RS Adelstein 2004 Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family J. Biol. Chem. 279 2800 2808 10.1074/jbc.M309981200 (Pubitemid 38114270)
10. MC Gutjahr J Rossy V Niggli 2005 Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells Exp. Cell. Res. 308 2 422 438 10.1016/j.yexcr.2005.05.001 (Pubitemid 43300534)
11. K Katoh Y Kano M Amano K Kaibuchi K Fujiwara 2001 Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts Am. J. Physiol. Cell. Physiol. 280 6 C1669 C1679
12. Y Katsuragawa M Yanagisawa A Inoue T Masaki 1989 Two distinct nonmuscle myosin-heavy-chain mRNAs are differentially expressed in various chicken tissues. Identification of a novel gene family of vertebrate non-sarcomeric myosin heavy chains Eur. J. Biochem. 184 611 616 10.1111/j.1432-1033.1989. tb15057.x
13. G Kirfel V Herzog 2004 Migration of epidermal keratinocytes: mechanisms, regulation, and biological significance Protoplasma 223 2-4 67 78
14. P Martin 1997 Wound healing-aiming for perfect skin regeneration Science 276 5309 75 81 10.1126/science.276.5309.75 (Pubitemid 27161246)
15. F Matsumura S Ono Y Yamakita G Totsukawa S Yamashiro 1998 Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells J. Cell Biol. 140 1 119 129 10.1083/jcb.140.1.119 (Pubitemid 28070900)
16. TJ Mitchison LP Cramer 1996 Actin-based cell motility and cell locomotion Cell 84 3 371 379 10.1016/S0092-8674(00)81281-7 (Pubitemid 26058562)
17. M Murata-Hori F Suizu T Iwasaki A Kikuchi H Hosoya 1999 ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells FEBS Lett. 451 81 84 10.1016/S0014-5793(99)00550-5 (Pubitemid 29236176)
18. M Nakayama M Amano A Katsumi T Kaneko S Kawabata M Takefuji K Kaibuchi 2005 Rho-kinase and myosin II activities are required for cell type and environment specific migration Genes Cells 10 2 107 117 10.1111/j.1365-2443. 2005.00823.x (Pubitemid 40287514)
19. V Niggli M Schmid A Nievergelt 2006 Differential roles of Rho-kinase and myosin light chain kinase in regulating shape, adhesion, and migration of HT1080 fibrosarcoma cells Biochem. Biophys. Res. Commun. 343 2 602 608 10.1016/j.bbrc.2006.03.022
20. S Papini D Cecchetti D Campani W Fitzgerald JC Grivel S Chen L Margolis RP Revoltella 2003 Isolation and clonal analysis of human epidermal keratinocyte stem cells in long-term culture Stem Cells 21 4 481 494 10.1634/stemcells.21-4- 481
21. CL Phillips Y Katsutoshi RS Adelstein 1995 Cloning of the cDNA encoding human nonmuscle myosin heavy chain-B and analysis of human tissues with isoform-specific antibodies J. Mus. Res. Cell. Motil. 16 379 389 10.1007/BF00114503
22. PL Post RL DeBiasio DL Taylor 1995 A fluorescent protein biosensor of myosin II regulatory light chain phosphorylation reports a gradient of phosphorylated myosin II in migrating cells Mol. Biol. Cell 6 12 1755 1768
23. JC Sandquist KI Swenson KA Demali K Burridge AR Means 2006 Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration J. Biol. Chem. 281 47 35873 35883 10.1074/jbc.M605343200 (Pubitemid 46041319)
24. G Totsukawa Y Wu Y Sasaki DJ Hartshorne Y Yamakita S Yamashiro F Matsumura 2004 Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts Cell Biol. 164 3 427 439 10.1083/jcb.200306172 (Pubitemid 38174770)
25. PT Tuazon JA Traugh 1984 Activation of actin-activated ATPase in smooth muscle by phosphorylation of myosin light chain with protease-activated kinase I J. Biol. Chem. 259 1 541 546
26. RA Worthylake K Burridge 2003 RhoA and ROCK promote migration by limiting membrane protrusions J. Biol. Chem. 278 15 13578 13584 10.1074/jbc.M211584200 (Pubitemid 36800134)
27. S Yamashiro G Totsukawa Y Yamakita Y Sasaki P Madaule T Ishizaki S Narumiya F Matsumura 2003 Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II Mol. Biol. Cell 14 5 1745 1756 10.1091/mbc.E02-07-0427 (Pubitemid 36583529)