Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - A mammalian DNA polymerase inhibitor

International Journal of Oncology

Volumn 36, Issue 3, 2010, Pages 577-584

  Kumamoto Yonezawa, Yuko ^a   Sasaki, Ryohei ^b   Suzuki, Yoko ^b   Matsui, Yuki ^a   Hada, Takahiko ^c   Uryu, Keisuke ^c   Sugimura, Kazuro ^b   Yoshida, Hiromi ^a   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Bizen Chemical Co Ltd   (Japan)

Author keywords

Anticancer therapy; Conjugated eicosapentaenoic acid; DNA damage; DNA polymerase; Enzyme inhibitor; Radiosensitivity

Indexed keywords

DOUBLE STRANDED DNA; ICOSAPENTAENOIC ACID; ANTINEOPLASTIC AGENT; DNA DIRECTED DNA POLYMERASE; LIPOCORTIN 5; NUCLEIC ACID SYNTHESIS INHIBITOR; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CANCER THERAPY; CELL SURVIVAL; CLONOGENIC ASSAY; COLON CARCINOMA; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG EFFICACY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IRRADIATION; PRIORITY JOURNAL; RADIOSENSITIVITY; COLON TUMOR; COMET ASSAY; DOSE RESPONSE; METABOLISM; NEOPLASMS; TREATMENT OUTCOME; TUMOR CELL LINE;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COLONIC NEOPLASMS; COMET ASSAY; DNA DAMAGE; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSAPENTAENOIC ACID; HUMANS; NEOPLASMS; NUCLEIC ACID SYNTHESIS INHIBITORS; TETRAZOLIUM SALTS; THIAZOLES; TREATMENT OUTCOME;

EID: 77149155961     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000532     Document Type: Article

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