-
5
-
-
0027201526
-
Optimum experimental designs for properties of a compartmental model
-
Atkinson AC, Chaloner K, Herzberg AM, Juritz J. Optimum experimental designs for properties of a compartmental model. Biometrics 1993 49 : 325 337.
-
(1993)
Biometrics
, vol.49
, pp. 325-337
-
-
Atkinson, A.C.1
Chaloner, K.2
Herzberg, A.M.3
Juritz, J.4
-
6
-
-
0000535561
-
Optimal-design for nonlinear-regression models
-
Haines LM. Optimal-design for nonlinear-regression models. Commun Stat Theory Methods 1993 22 : 1613 1627.
-
(1993)
Commun Stat Theory Methods
, vol.22
, pp. 1613-1627
-
-
Haines, L.M.1
-
7
-
-
0000685376
-
-
Elsevier Science. Amsterdam
-
Atkinson AC, Haines LM, Ghosh S, Rao CR. Designs for Nonlinear and Generalized Linear Models. Handbook of Statistics 13. Elsevier Science, Amsterdam, 1996 437 476.
-
(1996)
Designs for Nonlinear and Generalized Linear Models. Handbook of Statistics 13.
, pp. 437-476
-
-
Atkinson, A.C.1
Haines, L.M.2
Ghosh, S.3
Rao, C.R.4
-
8
-
-
0002419565
-
Design of experiments in non-linear situations
-
Box GEP, Lucas HL. Design of experiments in non-linear situations. Biometrika 1959 46 : 77 90.
-
(1959)
Biometrika
, vol.46
, pp. 77-90
-
-
Box, G.E.P.1
Lucas, H.L.2
-
9
-
-
0001238337
-
Some experiences with a nonlinear experimental design criterion
-
Box MJ. Some experiences with a nonlinear experimental design criterion. Technometrics 1970 12 : 569 589.
-
(1970)
Technometrics
, vol.12
, pp. 569-589
-
-
Box, M.J.1
-
12
-
-
0018387530
-
A program package for simulation and parameter estimation in pharmacokinetic systems
-
d'Argenio DZ, Schumitzky A. A program package for simulation and parameter estimation in pharmacokinetic systems. Comput Prog Biomed 1979 9 : 115 134.
-
(1979)
Comput Prog Biomed
, vol.9
, pp. 115-134
-
-
D'Argenio, D.Z.1
Schumitzky, A.2
-
13
-
-
0019843944
-
Optimal sampling times for pharmacokinetic experiments
-
d'Argenio DZ. Optimal sampling times for pharmacokinetic experiments. J Pharmacokinet Biopharm 1981 9 : 739 756.
-
(1981)
J Pharmacokinet Biopharm
, vol.9
, pp. 739-756
-
-
D'Argenio, D.Z.1
-
14
-
-
0019415655
-
Optimal design of experiments for the estimation of precise hyperbolic kinetic and binding parameters
-
Endrenyi L, Chan FY. Optimal design of experiments for the estimation of precise hyperbolic kinetic and binding parameters. J Theor Biol 1981 90 : 241 263.
-
(1981)
J Theor Biol
, vol.90
, pp. 241-263
-
-
Endrenyi, L.1
Chan, F.Y.2
-
16
-
-
0000963178
-
Optimal design in random-effects regression models
-
Mentré F, Mallet A, Baccar D. Optimal design in random-effects regression models. Biometrika 1997 84 : 429 442.
-
(1997)
Biometrika
, vol.84
, pp. 429-442
-
-
Mentré, F.1
Mallet, A.2
Baccar, D.3
-
17
-
-
0035107001
-
Development and implementation of the population Fisher information matrix for the evaluation of population pharmacokinetic designs
-
Retout S, Duffull S, Mentré F. Development and implementation of the population Fisher information matrix for the evaluation of population pharmacokinetic designs. Comput Methods Programs Biomed 2001 65 : 141 151.
-
(2001)
Comput Methods Programs Biomed
, vol.65
, pp. 141-151
-
-
Retout, S.1
Duffull, S.2
Mentré, F.3
-
18
-
-
0035049209
-
Optimal design of a population pharmacodynamic experiment for ivabradine
-
Duffull SB, Mentré F, Aarons L. Optimal design of a population pharmacodynamic experiment for ivabradine. Pharm Res 2001 18 : 83 9.
-
(2001)
Pharm Res
, vol.18
, pp. 83-9
-
-
Duffull, S.B.1
Mentré, F.2
Aarons, L.3
-
20
-
-
27144506012
-
The use of a modified Fedorov exchange algorithm to optimise sampling times for population pharmacokinetic experiments
-
Ogungbenro K, Graham G, Gueorguieva I, Aarons L. The use of a modified Fedorov exchange algorithm to optimise sampling times for population pharmacokinetic experiments. Comput Methods Programs Biomed 2005 80 : 115 125.
-
(2005)
Comput Methods Programs Biomed
, vol.80
, pp. 115-125
-
-
Ogungbenro, K.1
Graham, G.2
Gueorguieva, I.3
Aarons, L.4
-
21
-
-
33645817934
-
Optimal design for multivariate response pharmacokinetic models
-
Gueorguieva I, Aarons L, Ogungbenro K, Jorga KM, Rodgers T, Rowland M. Optimal design for multivariate response pharmacokinetic models. J Pharmacokinet Pharmacodyn 2006 33 : 97 124.
-
(2006)
J Pharmacokinet Pharmacodyn
, vol.33
, pp. 97-124
-
-
Gueorguieva, I.1
Aarons, L.2
Ogungbenro, K.3
Jorga, K.M.4
Rodgers, T.5
Rowland, M.6
-
22
-
-
0037286619
-
An evaluation of population D-optimal designs via pharmacokinetic simulations
-
Hooker AC, Foracchia M, Dodds MG, Vicini P. An evaluation of population D-optimal designs via pharmacokinetic simulations. Ann Biomed Eng 2003 31 : 98 111.
-
(2003)
Ann Biomed Eng
, vol.31
, pp. 98-111
-
-
Hooker, A.C.1
Foracchia, M.2
Dodds, M.G.3
Vicini, P.4
-
23
-
-
0025836658
-
Population pharmacokinetics: Theory and practice
-
Aarons L. Population pharmacokinetics: theory and practice. Br J Clin Pharmacol 1991 32 : 669 670.
-
(1991)
Br J Clin Pharmacol
, vol.32
, pp. 669-670
-
-
Aarons, L.1
-
25
-
-
33947177325
-
Optimal blood sampling time windows for parameter estimation in population pharmacokinetic experiments
-
Graham G, Aarons L. Optimal blood sampling time windows for parameter estimation in population pharmacokinetic experiments. Stat Med 2006 25 : 4004 4019.
-
(2006)
Stat Med
, vol.25
, pp. 4004-4019
-
-
Graham, G.1
Aarons, L.2
-
26
-
-
60749134432
-
An effective approach for obtaining optimal sampling windows for population pharmacokinetic experiments
-
Ogungbenro K, Aarons L. An effective approach for obtaining optimal sampling windows for population pharmacokinetic experiments. J Biopharm Stat 2008 19 : 174 189.
-
(2008)
J Biopharm Stat
, vol.19
, pp. 174-189
-
-
Ogungbenro, K.1
Aarons, L.2
-
27
-
-
0030032516
-
Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies
-
Aarons L, Balant LP, Mentré F, Morselli PL, Rowland M, Steimer JL et al. Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies. Eur J Clin Pharmacol 1996 49 : 251 254.
-
(1996)
Eur J Clin Pharmacol
, vol.49
, pp. 251-254
-
-
Aarons, L.1
Balant, L.P.2
Mentré, F.3
Morselli, P.L.4
Rowland, M.5
Steimer, J.L.6
-
28
-
-
44449106066
-
How many subjects are necessary for population pharmacokinetic experiments? Confidence interval approach
-
Ogungbenro K, Aarons L. How many subjects are necessary for population pharmacokinetic experiments? Confidence interval approach. Eur J Clin Pharmacol 2008 64 : 705 713.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 705-713
-
-
Ogungbenro, K.1
Aarons, L.2
-
30
-
-
0036428867
-
Bayesian analysis of population PK/PD models: General concepts and software
-
Lunn DJ, Best N, Thomas A, Wakefield J, Spiegelhalter D. Bayesian analysis of population PK/PD models: general concepts and software. J Pharmacokinet Pharmacodyn 2002 29 : 271 307.
-
(2002)
J Pharmacokinet Pharmacodyn
, vol.29
, pp. 271-307
-
-
Lunn, D.J.1
Best, N.2
Thomas, A.3
Wakefield, J.4
Spiegelhalter, D.5
-
31
-
-
0003818292
-
-
MRC Biostatistics Unit. Cambridge, UK
-
Spiegelhalter D, Thomas A, Best N, Lunn DJ. WinBUGS Version 1.4 User Manual. MRC Biostatistics Unit, Cambridge, UK, 2003.
-
(2003)
WinBUGS Version 1.4 User Manual.
-
-
Spiegelhalter, D.1
Thomas, A.2
Best, N.3
Lunn, D.J.4
-
32
-
-
0035863226
-
Design evaluation for a population pharmacokinetic study using clinical trial simulations: A case study
-
Kowalski KG, Hutmacher MM. Design evaluation for a population pharmacokinetic study using clinical trial simulations: a case study. Stat Med 2001 20 : 75 91.
-
(2001)
Stat Med
, vol.20
, pp. 75-91
-
-
Kowalski, K.G.1
Hutmacher, M.M.2
-
34
-
-
0035045467
-
Design and power of a population pharmacokinetic study
-
Lee PI. Design and power of a population pharmacokinetic study. Pharm Res 2001 18 : 75 82.
-
(2001)
Pharm Res
, vol.18
, pp. 75-82
-
-
Lee, P.I.1
-
35
-
-
32844466264
-
Sample size calculations based on generalized estimating equations for population pharmacokinetic experiments
-
Ogungbenro K, Aarons L, Graham G. Sample size calculations based on generalized estimating equations for population pharmacokinetic experiments. J Biopharm Stat 2006 16 : 135 150.
-
(2006)
J Biopharm Stat
, vol.16
, pp. 135-150
-
-
Ogungbenro, K.1
Aarons, L.2
Graham, G.3
-
36
-
-
4344613538
-
A sample size computation method for non-linear mixed effects models with applications to pharmacokinetic models
-
Kang D, Schwartz JB, Verotta D. A sample size computation method for non-linear mixed effects models with applications to pharmacokinetic models. Stat Med 2004 23 : 2551 2566.
-
(2004)
Stat Med
, vol.23
, pp. 2551-2566
-
-
Kang, D.1
Schwartz, J.B.2
Verotta, D.3
-
38
-
-
64149107347
-
Drug-drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: Application to midazolam and a phase i compound. Part 1: Comparison of uniresponse and multiresponse designs using PopDes
-
Chenel M, Bouzom F, Aarons L, Ogungbenro K. Drug-drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: application to midazolam and a phase I compound. Part 1: comparison of uniresponse and multiresponse designs using PopDes. J Pharmacokinet Pharmacodyn 2008 35 : 635 659.
-
(2008)
J Pharmacokinet Pharmacodyn
, vol.35
, pp. 635-659
-
-
Chenel, M.1
Bouzom, F.2
Aarons, L.3
Ogungbenro, K.4
-
39
-
-
64149090960
-
Drug-drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: Application to midazolam and a phase i compound. Part 2: Clinical trial results
-
Chenel M, Bouzom F, Cazade F, Ogungbenro K, Aarons L, Mentre F. Drug-drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: application to midazolam and a phase I compound. Part 2: clinical trial results. J Pharmacokinet Pharmacodyn 2008 35 : 661 681.
-
(2008)
J Pharmacokinet Pharmacodyn
, vol.35
, pp. 661-681
-
-
Chenel, M.1
Bouzom, F.2
Cazade, F.3
Ogungbenro, K.4
Aarons, L.5
Mentre, F.6
-
40
-
-
34249912369
-
Optimal design for multiresponse pharmacokinetic-pharmacodynamic models: Dealing with unbalanced designs
-
Ogungbenro K, Gueorguieva I, Majid O, Graham G, Aarons L. Optimal design for multiresponse pharmacokinetic-pharmacodynamic models: dealing with unbalanced designs. J Pharmacokinet Pharmacodyn 2007 34 : 313 331.
-
(2007)
J Pharmacokinet Pharmacodyn
, vol.34
, pp. 313-331
-
-
Ogungbenro, K.1
Gueorguieva, I.2
Majid, O.3
Graham, G.4
Aarons, L.5
-
41
-
-
40449086351
-
Incorporating correlation in interindividual variability for the optimal design of multiresponse pharmacokinetic experiments
-
Ogungbenro K, Graham G, Gueorguieva I, Aarons L. Incorporating correlation in interindividual variability for the optimal design of multiresponse pharmacokinetic experiments. J Biopharm Stat 2008 18 : 342 358.
-
(2008)
J Biopharm Stat
, vol.18
, pp. 342-358
-
-
Ogungbenro, K.1
Graham, G.2
Gueorguieva, I.3
Aarons, L.4
-
42
-
-
69949092783
-
Fisher information matrix for nonlinear mixed effects multiple response models: Evaluation of the appropriateness of the first order linearization using a pharmacokinetic/pharmacodynamic model
-
Bazzoli C, Retout S, Mentre F. Fisher information matrix for nonlinear mixed effects multiple response models: evaluation of the appropriateness of the first order linearization using a pharmacokinetic/pharmacodynamic model. Stat Med 2009 28 : 1940 1956.
-
(2009)
Stat Med
, vol.28
, pp. 1940-1956
-
-
Bazzoli, C.1
Retout, S.2
Mentre, F.3
-
43
-
-
33747140841
-
Simultaneous population optimal design for pharmacokinetic- pharmacodynamic experiments
-
Hooker A, Vicini P. Simultaneous population optimal design for pharmacokinetic-pharmacodynamic experiments. AAPS J 2005 7 : E759 85.
-
(2005)
AAPS J
, vol.7
, pp. 759-85
-
-
Hooker, A.1
Vicini, P.2
-
44
-
-
0000529193
-
Optimal Bayesian experimental design for linear models
-
Chaloner K. Optimal Bayesian experimental design for linear models. Ann Stat 1984 12 : 283 300.
-
(1984)
Ann Stat
, vol.12
, pp. 283-300
-
-
Chaloner, K.1
-
46
-
-
0028862831
-
Bayesian design criteria: Computation, comparison, and application to a pharmacokinetic and a pharmacodynamic model
-
Merle Y, Mentré F. Bayesian design criteria: computation, comparison, and application to a pharmacokinetic and a pharmacodynamic model. J Pharmacokinet Biopharm 1995 23 : 101 125.
-
(1995)
J Pharmacokinet Biopharm
, vol.23
, pp. 101-125
-
-
Merle, Y.1
Mentré, F.2
-
47
-
-
0032465920
-
Robust optimal design for the estimation of hyperparameters in population pharmacokinetics
-
Tod M, Mentré F, Merle Y, Mallet A. Robust optimal design for the estimation of hyperparameters in population pharmacokinetics. J Pharmacokinet Biopharm 1998 26 : 689 716.
-
(1998)
J Pharmacokinet Biopharm
, vol.26
, pp. 689-716
-
-
Tod, M.1
Mentré, F.2
Merle, Y.3
Mallet, A.4
-
49
-
-
0035882273
-
Cumulative logit models for ordinal data: A case study involving allergic rhinitis severity scores
-
Lunn DJ, Wakefield J, Racine-Poon A. Cumulative logit models for ordinal data: a case study involving allergic rhinitis severity scores. Stat Med 2001 20 : 2261 2285.
-
(2001)
Stat Med
, vol.20
, pp. 2261-2285
-
-
Lunn, D.J.1
Wakefield, J.2
Racine-Poon, A.3
|