Evaluation of bioactive saponins and triterpenoidal aglycons for their binding properties on human endothelin ETA and angiotensin AT 1 receptors

Phytotherapy Research

Volumn 18, Issue 9, 2004, Pages 729-736

  Caballero George, C ^a   Vanderheyden, P M L ^b   Okamoto, Y ^c   Masaki, T ^c   Mbwambo, Z ^d   Apers, S ^a   Gupta, M P ^e   Pieters, L ^a   Vauquelin, G ^b   Vlietinck, A ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c KYOTO UNIVERSITY   (Japan)

^d MUHIMBILI MEDICAL CENTRE   (Tanzania)

^e UNIVERSIDAD DE PANAMÁ   (Panama)

Author keywords

AT1 receptor; CHO cells; ETA receptor; Radioligand binding; Saponins; Triterpenes

Indexed keywords

ALPHA AMYRIN; ALPHA HEDERIN; ANGIOTENSIN 1 RECEPTOR; ASIATIC ACID; ASIATICOSIDE; BETA AMYRIN; BETA ESCIN; BETULIC ACID; BETULIN; CANDESARTAN; CANOPHYLLOL; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN 2; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR; FRIEDELIN; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; HEDERACOSIDE C; HEDERAGENIN; LUPEOL; MADECASSOSIDE; OLEANOLIC ACID; SAPONIN DERIVATIVE; TRITERPENE DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID;

ANIMAL CELL; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; DRUG INHIBITION; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; NONHUMAN;

ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; HUMANS; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; RADIOLIGAND ASSAY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ENDOTHELIN A; SAPONINS; TRITERPENES;

EID: 8344221970     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1521     Document Type: Article

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