nNOS and eNOS modulate cGMP formation and vascular response in contracting fast-twitch skeletal muscle

Physiological Genomics

Volumn 2000, Issue 2, 2000, Pages 21-27

  Lau, Kim S ^a   Grange, Robert W ^a   Isotani, Eiji ^a   Sarelius, Ingrid H ^b   Kamm, Kristine E ^a   Huang, Paul L ^c   Stull, James T ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Arteriolar relaxation; Endothelial nitric oxide synthase; Neuronal nitric oxide synthase

Indexed keywords

CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NOS1 PROTEIN, MOUSE; NOS3 PROTEIN, MOUSE;

ANIMAL; ARTICLE; BIOSYNTHESIS; BLOOD VESSEL; C57BL MOUSE; ELECTROSTIMULATION; FAST MUSCLE FIBER; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; MUSCLE CONTRACTION; PHYSIOLOGY; SKELETAL MUSCLE; SLOW MUSCLE FIBER; VASCULARIZATION; WESTERN BLOTTING;

ANIMALS; BLOOD VESSELS; BLOTTING, WESTERN; CYCLIC GMP; ELECTRIC STIMULATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE CONTRACTION; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SLOW-TWITCH; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III;

EID: 0347560375     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.2000.2.1.21     Document Type: Article

References (32)

1. Armstrong, R. B., M. D. Delp, E. F. Goljan, and M. H. Laughlin. Distribution of blood flow in muscles of miniature swine during exercise. J. Appl. Physiol. 62: 1285-1298, 1987.
2. Balon, T. W., and J. L. Nadler. Nitric oxide release is present from incubated skeletal muscle preparations. J. Appl. Physiol. 77: 2519-2521, 1994.
3. Bolotina, V. M., S. Najibi, J. J. Palacino, P. J. Pagano, and R. A. Cohen. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 368: 850-853, 1994.
4. Brenman, J. E., D. S. Chao, H. Xia, K. Aldape, and D. S. Bredt. Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy. Cell 82: 743-752, 1995.
5. Chang, W. J., S. T. Iannaccone, K. S. Lau, B. S. S. Masters, T. J. McCabe, K. McMillan, R. C. Padre, M. J. Spencer, J. G. Tidball, and J. T. Stull. Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy. Proc. Natl. Acad. Sci. USA 93: 9142-9147, 1996.
6. Dyke, C. K., D. N. Proctor, N. M. Dietz, and M. J. Joyner. Role of nitric oxide in exercise hyperaemia during prolonged rhythmic handgripping in humans. J. Physiol. 488: 259-265, 1995.
7. Faraci, F. M., D. S. Sigmund, G. Sheshely, M. Nobuyo, and D. Heistad. Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. Am. J. Physiol. Heart Circ. Physiol. 274: H564-H570, 1998.
8. + channels and contraction of cultured smooth muscle cells of porcine coronary artery. J. Pharmacol. Exp. Ther. 256: 371-377, 1991.
9. Hellsten, Y., and U. Fransden. Adenosine metabolism in primary skeletal muscle cells in culture. J. Physiol. 504: 695-704, 1997.
10. Huang, P. L., Z. Huang, H. Mashimoto, K. D. Bloch M. A. Moskowitz, J. A. Beven, and M. C. Fishman. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 377: 237-242, 1995.
11. Huang, P. L., T. M. Dawson, D. S. Bredt, S. H. Snyder, and M. C. Fishman. Targeted disruption of the neuronal nitric oxide synthase gene. Cell 75: 1273-1286, 1993.
12. Joyner, M. J., and N. M. Dietz. Nitric oxide and vasodilation in human limbs. J. Appl. Physiol. 83: 1785-96, 1997.
13. Kobzik, L., M. B. Reid, D. S. Bredt, J. S. Stamler. Nitric oxide in skeletal muscle. Nature 372: 546-548, 1994.
14. Kurjiaka, D. T., and S. S. Segal. Conducted vasodilation elevates flow in arteriolar networks of hamster striated muscle. Am. J. Physiol. Heart Circ. Physiol. 269: H1723-H1728, 1995.
15. Lash, J. M. Regulation of skeletal muscle blood flow during contractions. Proc. Soc. Exp. Biol. Med. 211: 218-235, 1996.
16. Lau, K. S., R. W. Grange, W.-J. Chang, K. E. Kamm, I. Sarelius, and J. T. Stull. Skeletal muscle contractions stimulate cGMP formation and attenuate vascular smooth muscle myosin phosphorylation via nitric oxide. FEBS Lett. 431: 71-74, 1998.
17. Laughlin, M. H., R. J. Korthuis, D. J. Duncker, and R. J. Bache. Control of blood flow to cardiac and skeletal muscle during exercise. In: Handbook of Physiology. Exercise: Regulation and Integration of Multiple Systems. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 12, chapt. 16, p. 705-769.
18. Lincoln, T. M., T. L. Cornwell, P. Komalavilas, L. A. Macmillan-Crow, and N. Boerth. The nitric oxide-cyclic GMP signaling system. In: Biochemistry of Smooth Muscle Contraction, edited by M. Barany. New York: Academic Press, 1996, p. 257-268.
19. Marietta, MA. Nitric oxide: biosynthesis and biological significance. Trends Biochem. Sci. 14: 488-492, 1989.
20. Marshall, J. J., E. P. Wei, and H. A. Kontos. Independent blockade of cerebral vasodilation from acetylcholine and nitric oxide. Am. J. Physiol Heart Circ. Physiol. 255: H847-H854, 1988.
21. Meng, W., J. Ma, C. Ayata, H. Hara, P. L. Huang, M. C. Fishman, and M. A. Moskowitz. Ach dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms. Am. J. Physiol. Heart Circ. Physiol. 271: H1145-H1150, 1996.
22. Meng, W. C. Ayata, C. Waeber, P. L. Huang, and M. A. Moskowitz. Neuronal NOS-cGMP-dependent Ach-induced relaxation in pial arterioles of endothelial NOS knockout mice. Am. J. Physiol. Heart Circ. Physiol. 274: H411-H415, 1998.
23. Nestler, E. J., K. G Beam, and P. Greengard. Nicotinic cholinergic stimulation increases cyclic GMP levels in vertebrate skeletal muscle. Nature 275: 451-453, 1978.
24. Palmer, R. M. J., and S. Moncada. A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells. Biochem. Biophys. Res. Commun. 158: 348-352, 1989.
25. Panavelas, J. G., and G. Burnstock. Ultrastructural localization of choline acetyltransferase in vascular endothelial cells in rat brain. Nature 316: 724-725, 1985.
26. Pohl, U., and C. and de Wit. A unique role of NO in the control of blood flow. News Physiol. Sci. 14: 74-80, 1999.
27. Pries, A. R., J. Heide, K. Ley, K.-F. Klotz, and P. Gaetgens. Effect of oxygen tension on regulation of arteriolar diameter in skeletal muscle in situ. Microvasc. Res. 49: 289-299, 1995.
28. Proctor, K. G., and B. R. Duling. Adenosine and free-flow functional hyperemia in striated muscle. Am. J. Physiol. Heart Circ. Physiol. 242: H688-H697, 1982.
29. Silvagno, F., H. Xia, D. S. Bredt. Neuronal nitric-oxide synthase-μ, an alternatively spliced isoform expressed in differentiated skeletal muscle. J. Biol. Chem. 271: 11204-11208, 1996.
30. + channel activity and vascular tone in renal arterioles. Circ. Res. 83: 1089-1079, 1998.
31. Thomas, G. D., J. Hansen, and R. G. Victor. Inhibition of alpha 2-adrenergic vasoconstriction during contraction of glycolytic, not oxidative, rat hindlimb muscle. Am. J. Physiol. Heart Circ. Physiol 266: H920-H929, 1994.
32. Thomas, G. D., M. Sander, K. S. Lau, P. L. Huang, J. T. Stull, and R. G. Victor. Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle. Proc. Natl. Acad. Sci. USA 95: 15090-15095, 1998.