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Volumn 14, Issue 3, 2010, Pages 295.e1-295.e9

Effect of chronic intra-peritoneally administered chimeric peptide of met-enkephalin and FMRFa-[d-Ala2]YFa-on antinociception and opioid receptor regulation

Author keywords

Antinociception; Chimeric opioid peptides; Opioid receptor expression; Tolerance; YFa

Indexed keywords

DELTA OPIATE RECEPTOR; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; KAPPA OPIATE RECEPTOR; METENKEPHALIN[6 ARGININE 7 PHENYLALANINE]; MU OPIATE RECEPTOR; NALOXONAZINE; NALTRINDOLE; NORBINALTORPHIMINE; OPIATE AGONIST; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE;

EID: 77049118748     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2009.05.014     Document Type: Article
Times cited : (4)

References (58)
  • 1
    • 0022051507 scopus 로고
    • Characterization of [3H][2-D-penicillamine 5-D-penicillamine]-enkephalin binding to delta opiate receptors in the rat brain and neuroblastoma-glioma hybrid cell line (NG 108-15)
    • Akiyama K., Gee K.W., Mosberg H.I., Hruby V.J., and Yamamura H.I. Characterization of [3H][2-D-penicillamine 5-D-penicillamine]-enkephalin binding to delta opiate receptors in the rat brain and neuroblastoma-glioma hybrid cell line (NG 108-15). Proc Natl Acad Sci USA 82 (1985) 2543-2547
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2543-2547
    • Akiyama, K.1    Gee, K.W.2    Mosberg, H.I.3    Hruby, V.J.4    Yamamura, H.I.5
  • 2
    • 0024421240 scopus 로고
    • Characterization of rat spinal cord receptors to FLFQPQRFamide, a mammalian morphine modulating peptide: a binding study
    • Allard M., Geoffre S., Legendre P., Vincent J.D., and Simonnet G. Characterization of rat spinal cord receptors to FLFQPQRFamide, a mammalian morphine modulating peptide: a binding study. Brain Res 500 (1989) 169-176
    • (1989) Brain Res , vol.500 , pp. 169-176
    • Allard, M.1    Geoffre, S.2    Legendre, P.3    Vincent, J.D.4    Simonnet, G.5
  • 3
    • 0024392509 scopus 로고
    • Dermenkephalin (Tyr-d-Met-Phe-His-Leu-Met-Asp-NH2): a potent and fully specific agonist for the delta opioid receptor
    • Amiche M., Sagan S., Mor A., Delfour A., and Nicolas P. Dermenkephalin (Tyr-d-Met-Phe-His-Leu-Met-Asp-NH2): a potent and fully specific agonist for the delta opioid receptor. Mol Pharmacol 35 (1989) 774-779
    • (1989) Mol Pharmacol , vol.35 , pp. 774-779
    • Amiche, M.1    Sagan, S.2    Mor, A.3    Delfour, A.4    Nicolas, P.5
  • 4
    • 0030611354 scopus 로고    scopus 로고
    • Met5-enkephalin-Arg6-Phe7, an endogenous neuropeptide, binds to multiple opioid and nonopioid sites in rat brain
    • Benyhe S., Farkas J., Toth G., and Wollemann M. Met5-enkephalin-Arg6-Phe7, an endogenous neuropeptide, binds to multiple opioid and nonopioid sites in rat brain. J Neurosci Res 48 (1997) 249-258
    • (1997) J Neurosci Res , vol.48 , pp. 249-258
    • Benyhe, S.1    Farkas, J.2    Toth, G.3    Wollemann, M.4
  • 5
    • 10944232800 scopus 로고    scopus 로고
    • Post-transcriptional expression regulation in the yeast Saccharomyces cerevisiae on a genomic scale
    • Beyer A., Hollunder J., Nasheuer H.P., and Wilhelm T. Post-transcriptional expression regulation in the yeast Saccharomyces cerevisiae on a genomic scale. Mol Cell Proteomics 3 (2004) 1083-1092
    • (2004) Mol Cell Proteomics , vol.3 , pp. 1083-1092
    • Beyer, A.1    Hollunder, J.2    Nasheuer, H.P.3    Wilhelm, T.4
  • 6
    • 0025185668 scopus 로고
    • Downregulation of brain and spinal cord mu-opiate receptors in morphine tolerant-dependent rats
    • Bhargava H.N., and Gulati A. Downregulation of brain and spinal cord mu-opiate receptors in morphine tolerant-dependent rats. Eur J Pharmacol 190 (1990) 305-311
    • (1990) Eur J Pharmacol , vol.190 , pp. 305-311
    • Bhargava, H.N.1    Gulati, A.2
  • 7
    • 0027482916 scopus 로고
    • Effects of naltrexone on the binding of [3H]d-Ala2, Met-Phe4, Gly-ol5-enkephalin to brain regions and spinal cord and pharmacological responses to morphine in the rat
    • Bhargava H.N., Matwyshyn G.A., Reddy P.L., and Veeranna. Effects of naltrexone on the binding of [3H]d-Ala2, Met-Phe4, Gly-ol5-enkephalin to brain regions and spinal cord and pharmacological responses to morphine in the rat. Gen Pharmacol 24 (1993) 1351-1357
    • (1993) Gen Pharmacol , vol.24 , pp. 1351-1357
    • Bhargava, H.N.1    Matwyshyn, G.A.2    Reddy, P.L.3    Veeranna4
  • 8
    • 0030865079 scopus 로고    scopus 로고
    • Effect of 7-nitroindazole on tolerance to morphine, U-50, 488H and d-Pen2, d-Pen5] enkephalin in mice
    • Bhargava H.N., Cao Y.J., and Zhao G.M. Effect of 7-nitroindazole on tolerance to morphine, U-50, 488H and d-Pen2, d-Pen5] enkephalin in mice. Peptides 18 (1997) 797-800
    • (1997) Peptides , vol.18 , pp. 797-800
    • Bhargava, H.N.1    Cao, Y.J.2    Zhao, G.M.3
  • 9
    • 0041353619 scopus 로고    scopus 로고
    • Mouse kappa-opioid receptor mRNA differential transport in neurons
    • Bi J., Hu X., Loh H.H., and Wei L.N. Mouse kappa-opioid receptor mRNA differential transport in neurons. Mol Pharmacol 64 (2003) 594-599
    • (2003) Mol Pharmacol , vol.64 , pp. 594-599
    • Bi, J.1    Hu, X.2    Loh, H.H.3    Wei, L.N.4
  • 10
    • 0026625241 scopus 로고
    • Antidiarrheal and colonic antipropulsive effects of spinal and supraspinal administration of the natural delta opioid receptor agonist [d-Ala2]deltorphin II in the rat
    • Broccardo M., and Improta G. Antidiarrheal and colonic antipropulsive effects of spinal and supraspinal administration of the natural delta opioid receptor agonist [d-Ala2]deltorphin II in the rat. Eur J Pharmacol 218 (1992) 69-73
    • (1992) Eur J Pharmacol , vol.218 , pp. 69-73
    • Broccardo, M.1    Improta, G.2
  • 11
    • 0032545739 scopus 로고    scopus 로고
    • Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I
    • Burford N.T., Tolbert L.M., and Sadee W. Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I. Eur J Pharmacol 342 (1998) 123-126
    • (1998) Eur J Pharmacol , vol.342 , pp. 123-126
    • Burford, N.T.1    Tolbert, L.M.2    Sadee, W.3
  • 12
    • 0343376475 scopus 로고    scopus 로고
    • Quantitative analysis of mu and delta opioid receptor gene expression in rat brain and peripheral ganglia using competitive polymerase chain reaction
    • Buzas B., and Cox B.M. Quantitative analysis of mu and delta opioid receptor gene expression in rat brain and peripheral ganglia using competitive polymerase chain reaction. Neuroscience 76 (1997) 479-489
    • (1997) Neuroscience , vol.76 , pp. 479-489
    • Buzas, B.1    Cox, B.M.2
  • 13
    • 0029784667 scopus 로고    scopus 로고
    • Mu and delta opioid receptor gene expression after chronic treatment with opioid agonist
    • Buzas B., Rosenberger J., and Cox B.M. Mu and delta opioid receptor gene expression after chronic treatment with opioid agonist. Neuroreport 7 (1996) 1505-1508
    • (1996) Neuroreport , vol.7 , pp. 1505-1508
    • Buzas, B.1    Rosenberger, J.2    Cox, B.M.3
  • 14
    • 0037220621 scopus 로고    scopus 로고
    • Opioid peptides, opioid receptors and mechanism of down regulation
    • Chaturvedi K. Opioid peptides, opioid receptors and mechanism of down regulation. Indian J Exp Biol 41 (2003) 5-13
    • (2003) Indian J Exp Biol , vol.41 , pp. 5-13
    • Chaturvedi, K.1
  • 15
    • 0027454746 scopus 로고
    • Opioid-induced stimulation of fetal respiratory activity by [d-Ala2]deltorphin I
    • Cheng P.Y., Wu D., Decena J., Soong Y., McCabe S., and Szeto H.H. Opioid-induced stimulation of fetal respiratory activity by [d-Ala2]deltorphin I. Eur J Pharmacol 230 (1993) 85-88
    • (1993) Eur J Pharmacol , vol.230 , pp. 85-88
    • Cheng, P.Y.1    Wu, D.2    Decena, J.3    Soong, Y.4    McCabe, S.5    Szeto, H.H.6
  • 16
    • 0242403121 scopus 로고    scopus 로고
    • Region selective upregulation of micro-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice
    • Clarke S., Zimmer A., Zimmer A.M., Hill R.G., and Kitchen I. Region selective upregulation of micro-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice. Neuroscience 122 (2003) 479-489
    • (2003) Neuroscience , vol.122 , pp. 479-489
    • Clarke, S.1    Zimmer, A.2    Zimmer, A.M.3    Hill, R.G.4    Kitchen, I.5
  • 17
    • 0343183961 scopus 로고    scopus 로고
    • Deltorphin II analogues with 6-hydroxy-2-aminotetralin-2-carboxylic acid in position 1
    • Darula Z., Kover K.E., Monory K., Borsodi A., Mako E., Ronai A., et al. Deltorphin II analogues with 6-hydroxy-2-aminotetralin-2-carboxylic acid in position 1. J Med Chem 43 (2000) 1359-1366
    • (2000) J Med Chem , vol.43 , pp. 1359-1366
    • Darula, Z.1    Kover, K.E.2    Monory, K.3    Borsodi, A.4    Mako, E.5    Ronai, A.6
  • 18
    • 0020003587 scopus 로고
    • [3H]Tyr-d-Ser-Gly-Phe-Leu-Thr: a specific probe for the delta-opiate receptor subtype in brain membranes
    • David M., Moisand C., Meunier J.C., Morgat J.L., Gacel G., and Roques B.P. [3H]Tyr-d-Ser-Gly-Phe-Leu-Thr: a specific probe for the delta-opiate receptor subtype in brain membranes. Eur J Pharmacol 78 (1982) 385-387
    • (1982) Eur J Pharmacol , vol.78 , pp. 385-387
    • David, M.1    Moisand, C.2    Meunier, J.C.3    Morgat, J.L.4    Gacel, G.5    Roques, B.P.6
  • 19
    • 0024412166 scopus 로고
    • Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding sites
    • Erspamer V., Melchiorri P., Falconieri-Erspamer G., Negri L., Corsi R., Severini C., et al. Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding sites. Proc Natl Acad Sci USA 86 (1989) 5188-5192
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5188-5192
    • Erspamer, V.1    Melchiorri, P.2    Falconieri-Erspamer, G.3    Negri, L.4    Corsi, R.5    Severini, C.6
  • 20
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
    • Ferguson Stephen.S.G. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53 (2001) 1-24
    • (2001) Pharmacol Rev , vol.53 , pp. 1-24
    • Ferguson, Stephen.S.G.1
  • 21
    • 0022993085 scopus 로고
    • Existence of antiopiate system as illustrated by MIF-1/Tyr-MIF-1
    • Galina H.Z., and Kastin A.J. Existence of antiopiate system as illustrated by MIF-1/Tyr-MIF-1. Life Sci 39 (1986) 2153-2159
    • (1986) Life Sci , vol.39 , pp. 2153-2159
    • Galina, H.Z.1    Kastin, A.J.2
  • 22
    • 0005081183 scopus 로고
    • Modulation of opioid receptors by antiopioid peptides
    • Tseng L.F. (Ed), Harwood Academic Publishers, gmbh, Singapore
    • Goodman C.B., Elmer G.I., Yang H.-Y.T., Lee C.H., and Rothman R.B. Modulation of opioid receptors by antiopioid peptides. In: Tseng L.F. (Ed). The pharmacology of opioid peptides (1995), Harwood Academic Publishers, gmbh, Singapore 303-319
    • (1995) The pharmacology of opioid peptides , pp. 303-319
    • Goodman, C.B.1    Elmer, G.I.2    Yang, H.-Y.T.3    Lee, C.H.4    Rothman, R.B.5
  • 23
    • 0029953168 scopus 로고    scopus 로고
    • Downregulation of m-opioid binding sites following chronic administration of NPFF and morphine
    • Goodman C.B., Emilien B., Becketts K., Cadet J.L., and Rothman R.B. Downregulation of m-opioid binding sites following chronic administration of NPFF and morphine. Peptides 17 (1996) 389-397
    • (1996) Peptides , vol.17 , pp. 389-397
    • Goodman, C.B.1    Emilien, B.2    Becketts, K.3    Cadet, J.L.4    Rothman, R.B.5
  • 24
    • 0027180641 scopus 로고
    • Antinociceptive effects of intrathecally administered F8Famide and FMRFamide in the rat
    • Gouarderes C., Sutak M., Zajac J.-M., and Jhamandas K. Antinociceptive effects of intrathecally administered F8Famide and FMRFamide in the rat. Eur J Pharmacol 237 (1993) 73-81
    • (1993) Eur J Pharmacol , vol.237 , pp. 73-81
    • Gouarderes, C.1    Sutak, M.2    Zajac, J.-M.3    Jhamandas, K.4
  • 25
    • 0141920354 scopus 로고    scopus 로고
    • Comparing protein abundance and mRNA expression levels on a genomic scale
    • Greenbaum D., Colangelo C., Williams K., and Gerstein M. Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol 4 (2003) 1171-1178
    • (2003) Genome Biol , vol.4 , pp. 1171-1178
    • Greenbaum, D.1    Colangelo, C.2    Williams, K.3    Gerstein, M.4
  • 26
    • 0020701590 scopus 로고
    • The molluscan neurosecretory peptide FMRFamide: comparative pharmacology and relationship to the enkephalins
    • Greenberg M.J., Painter S.D., Dobble K.E., Naggle G.T., Price D.A., and Lehman H.K. The molluscan neurosecretory peptide FMRFamide: comparative pharmacology and relationship to the enkephalins. Fed Proc 42 (1983) 82-86
    • (1983) Fed Proc , vol.42 , pp. 82-86
    • Greenberg, M.J.1    Painter, S.D.2    Dobble, K.E.3    Naggle, G.T.4    Price, D.A.5    Lehman, H.K.6
  • 27
    • 0032888076 scopus 로고    scopus 로고
    • Chimeric peptide of met-enkephalin and FMRFa induces antinociception and attenuates development of tolerance to morphine antinociception
    • Gupta S., Pasha S., Gupta Y.K., and Bhardwaj D.K. Chimeric peptide of met-enkephalin and FMRFa induces antinociception and attenuates development of tolerance to morphine antinociception. Peptides 20 (1999) 471-478
    • (1999) Peptides , vol.20 , pp. 471-478
    • Gupta, S.1    Pasha, S.2    Gupta, Y.K.3    Bhardwaj, D.K.4
  • 29
    • 7444252728 scopus 로고    scopus 로고
    • Internalization and downregulation of mu opioid receptors by endomorphins and morphine in SH-SY5Y human neuroblastoma cells
    • Horner K.A., and Zadina J.E. Internalization and downregulation of mu opioid receptors by endomorphins and morphine in SH-SY5Y human neuroblastoma cells. Brain Res 1028 (2004) 121-132
    • (2004) Brain Res , vol.1028 , pp. 121-132
    • Horner, K.A.1    Zadina, J.E.2
  • 31
    • 0025770914 scopus 로고
    • Differential antagonism of opioid delta antinociception by [d-Ala2,Leu5,Cys6]enkephalin and naltrindole 50-isothiocyanate: evidence for delta receptor subtypes
    • Jiang Q., Takemori A.E., Sultana M., Portoghese P.S., Bowen W.D., Mosberg H.I., et al. Differential antagonism of opioid delta antinociception by [d-Ala2,Leu5,Cys6]enkephalin and naltrindole 50-isothiocyanate: evidence for delta receptor subtypes. J Pharmacol Exp Ther 257 (1991) 1069-1075
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 1069-1075
    • Jiang, Q.1    Takemori, A.E.2    Sultana, M.3    Portoghese, P.S.4    Bowen, W.D.5    Mosberg, H.I.6
  • 33
    • 0022403798 scopus 로고
    • Effect of pertussis toxin treatment on the downregulation of opiate receptors in neuroblastoma X glioma NG108-15 hybrid cells
    • Law P.Y., Louie A.K., and Loh H.H. Effect of pertussis toxin treatment on the downregulation of opiate receptors in neuroblastoma X glioma NG108-15 hybrid cells. J Biol Chem 260 (1985) 14818-14823
    • (1985) J Biol Chem , vol.260 , pp. 14818-14823
    • Law, P.Y.1    Louie, A.K.2    Loh, H.H.3
  • 34
    • 4644323278 scopus 로고    scopus 로고
    • Insights into the receptor transcription and signaling: implications in opioid tolerance and dependence
    • Law P.Y., Loh H.H., and Wei L.N. Insights into the receptor transcription and signaling: implications in opioid tolerance and dependence. Neuropharmacology 47 (2004) 300-311
    • (2004) Neuropharmacology , vol.47 , pp. 300-311
    • Law, P.Y.1    Loh, H.H.2    Wei, L.N.3
  • 35
    • 0034130646 scopus 로고    scopus 로고
    • The effect of nimodipine on opioid antagonist-induced upregulation and supersensitivity
    • Lee S.C., and Yoburn B.C. The effect of nimodipine on opioid antagonist-induced upregulation and supersensitivity. Pharmacol Biochem Behav 66 (2000) 347-351
    • (2000) Pharmacol Biochem Behav , vol.66 , pp. 347-351
    • Lee, S.C.1    Yoburn, B.C.2
  • 36
    • 2442678807 scopus 로고    scopus 로고
    • Agonist-induced regulation and trafficking of kappa opioid receptors
    • Liu-Chen L.Y. Agonist-induced regulation and trafficking of kappa opioid receptors. Life Sci 75 (2004) 511-536
    • (2004) Life Sci , vol.75 , pp. 511-536
    • Liu-Chen, L.Y.1
  • 37
    • 0025195866 scopus 로고
    • FMRF-NH2 like mammalian peptide precipitates opiate-withdrawal syndrome in the rat
    • Malin D.H., Lake J.R., Fowler D.E., Hammond M.V., Brown S.L., Levya J.E., et al. FMRF-NH2 like mammalian peptide precipitates opiate-withdrawal syndrome in the rat. Peptides 11 (1990) 277-280
    • (1990) Peptides , vol.11 , pp. 277-280
    • Malin, D.H.1    Lake, J.R.2    Fowler, D.E.3    Hammond, M.V.4    Brown, S.L.5    Levya, J.E.6
  • 38
    • 0025197324 scopus 로고
    • FMRF-NH2 like mammalian octapeptide: possible role in opiate dependence and abstinence
    • Malin D.H., Lake J.R., Hammond M.V., Fowler D.E., Rogillio R.B., Brown S.L., et al. FMRF-NH2 like mammalian octapeptide: possible role in opiate dependence and abstinence. Peptides 11 (1990) 969-972
    • (1990) Peptides , vol.11 , pp. 969-972
    • Malin, D.H.1    Lake, J.R.2    Hammond, M.V.3    Fowler, D.E.4    Rogillio, R.B.5    Brown, S.L.6
  • 39
    • 0032948235 scopus 로고    scopus 로고
    • Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2
    • Mcconalogue K., Grady E.F., Minnis J., Balestra B., Tonini M., Brecha N.C., et al. Activation and internalization of the mu-opioid receptor by the newly discovered endogenous agonists, endomorphin-1 and endomorphin-2. Neuroscience 90 (1999) 1051-1059
    • (1999) Neuroscience , vol.90 , pp. 1051-1059
    • Mcconalogue, K.1    Grady, E.F.2    Minnis, J.3    Balestra, B.4    Tonini, M.5    Brecha, N.C.6
  • 40
    • 33845790070 scopus 로고    scopus 로고
    • Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: a quantitative analysis
    • Nie L., Wu G., and Zhang W. Correlation of mRNA expression and protein abundance affected by multiple sequence features related to translational efficiency in Desulfovibrio vulgaris: a quantitative analysis. Genetics 174 (2006) 2229-2243
    • (2006) Genetics , vol.174 , pp. 2229-2243
    • Nie, L.1    Wu, G.2    Zhang, W.3
  • 41
    • 0037622772 scopus 로고    scopus 로고
    • The expression of δ- and κ-opioid receptor is enhanced during intestinal Inflammation in mice
    • Pol O., Palacio R.J., and Puig M.M. The expression of δ- and κ-opioid receptor is enhanced during intestinal Inflammation in mice. JPET 306 (2003) 455-462
    • (2003) JPET , vol.306 , pp. 455-462
    • Pol, O.1    Palacio, R.J.2    Puig, M.M.3
  • 42
    • 33746294077 scopus 로고    scopus 로고
    • Interleukin-1 beta contributes to the upregulation of Kappa opioid receptor mrna in dorsal root ganglia in response to peripheral inflammation
    • Puehler W., Rittnera H.L., Mousa S.A., Brack A., Krause H., Steina C., et al. Interleukin-1 beta contributes to the upregulation of Kappa opioid receptor mrna in dorsal root ganglia in response to peripheral inflammation. Neuroscience 141 (2006) 989-998
    • (2006) Neuroscience , vol.141 , pp. 989-998
    • Puehler, W.1    Rittnera, H.L.2    Mousa, S.A.3    Brack, A.4    Krause, H.5    Steina, C.6
  • 43
    • 0025034261 scopus 로고
    • Effect of [d-Met2]FMRFamide and other FMRFamide related peptides on mouse colonic propulsive motility: a structure-activity relationship study
    • Raffa R.B., and Jacoby H.I. Effect of [d-Met2]FMRFamide and other FMRFamide related peptides on mouse colonic propulsive motility: a structure-activity relationship study. J Pharmacol Exp Ther 254 (1990) 809-814
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 809-814
    • Raffa, R.B.1    Jacoby, H.I.2
  • 44
    • 0028285707 scopus 로고
    • Low affinity of FMRFa and four FaRPs(FMRFamide related peptides), including the mammalian-derived FaRPs F8Fa(NPFF) and A18Fa, for opioid μ, δ, κ1, κ2a or κ2b receptors
    • Raffa R.B., Kim A., Rice K.C., De Costa B.R., Codd E.E., and Rothman R.B. Low affinity of FMRFa and four FaRPs(FMRFamide related peptides), including the mammalian-derived FaRPs F8Fa(NPFF) and A18Fa, for opioid μ, δ, κ1, κ2a or κ2b receptors. Peptides 15 (1994) 401-404
    • (1994) Peptides , vol.15 , pp. 401-404
    • Raffa, R.B.1    Kim, A.2    Rice, K.C.3    De Costa, B.R.4    Codd, E.E.5    Rothman, R.B.6
  • 45
    • 0019227107 scopus 로고
    • Metenkephalin-Arg6-Phe7, present in high amounts in brain of rat, cattle and man, is an opioid agonist
    • Rossier J., Audigier Y., Ling N., Cros J., and Udenfriend S. Metenkephalin-Arg6-Phe7, present in high amounts in brain of rat, cattle and man, is an opioid agonist. Nature 288 (1980) 88-90
    • (1980) Nature , vol.288 , pp. 88-90
    • Rossier, J.1    Audigier, Y.2    Ling, N.3    Cros, J.4    Udenfriend, S.5
  • 47
    • 1942456664 scopus 로고    scopus 로고
    • [d-Ala2,N-MePhe4,Gly-ol5]enkephalin-induced internalization of the micro opioid receptor in the spinal cord of morphine tolerant rats
    • Trafton J.A., and Basbaum A.I. [d-Ala2,N-MePhe4,Gly-ol5]enkephalin-induced internalization of the micro opioid receptor in the spinal cord of morphine tolerant rats. Neuroscience 125 (2004) 541-543
    • (2004) Neuroscience , vol.125 , pp. 541-543
    • Trafton, J.A.1    Basbaum, A.I.2
  • 48
    • 43149111300 scopus 로고    scopus 로고
    • YFa, a chimeric opioid peptide, induces kappa-specific antinociception with no tolerance development during 6 days of chronic treatment
    • Vats I.D., Dolt K.S., Kumar K., Karar J., Nath M., and Pasha S. YFa, a chimeric opioid peptide, induces kappa-specific antinociception with no tolerance development during 6 days of chronic treatment. J Neurosci Res 86 (2008) 1599-1607
    • (2008) J Neurosci Res , vol.86 , pp. 1599-1607
    • Vats, I.D.1    Dolt, K.S.2    Kumar, K.3    Karar, J.4    Nath, M.5    Pasha, S.6
  • 49
    • 0345167178 scopus 로고    scopus 로고
    • Differential effects of agonists on adenylyl cyclase superactivation mediated by the kappa opioid receptors: adenylyl cyclase superactivation is independent of agonist-induced phosphorylation, desensitization, internalization, and downregulation
    • Wang Y., Li J.G., Huang P., Xu W., and Liu-Chen L.Y. Differential effects of agonists on adenylyl cyclase superactivation mediated by the kappa opioid receptors: adenylyl cyclase superactivation is independent of agonist-induced phosphorylation, desensitization, internalization, and downregulation. J Pharmacol Exp Ther 307 (2003) 1127-1134
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 1127-1134
    • Wang, Y.1    Li, J.G.2    Huang, P.3    Xu, W.4    Liu-Chen, L.Y.5
  • 50
    • 0036462450 scopus 로고    scopus 로고
    • Regulation of opioid receptor expression
    • Wei L.N., and Loh H.H. Regulation of opioid receptor expression. Curr Opin Pharmacol 2 (2002) 69-75
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 69-75
    • Wei, L.N.1    Loh, H.H.2
  • 51
    • 0033980745 scopus 로고    scopus 로고
    • Post-transcriptional regulation of mouse kappa-opioid receptor expression
    • Wei L.N., Hu X., Bi J., and Loh H. Post-transcriptional regulation of mouse kappa-opioid receptor expression. Mol Pharmacol 57 (2000) 401-408
    • (2000) Mol Pharmacol , vol.57 , pp. 401-408
    • Wei, L.N.1    Hu, X.2    Bi, J.3    Loh, H.4
  • 52
    • 2442701942 scopus 로고    scopus 로고
    • Post-transcriptional regulation of opioid receptors in the nervous system
    • Wei L.N., Law P.Y., and Loh H.H. Post-transcriptional regulation of opioid receptors in the nervous system. Front Biosci 9 (2004) 1665-1679
    • (2004) Front Biosci , vol.9 , pp. 1665-1679
    • Wei, L.N.1    Law, P.Y.2    Loh, H.H.3
  • 53
    • 0011981114 scopus 로고
    • Isolation, sequencing, synthesis and pharmacological characterization of two brain neuropeptides that modulate the action of morphine
    • Yang H.-Y.T., Fratta W., Majane E.A., and Costa E. Isolation, sequencing, synthesis and pharmacological characterization of two brain neuropeptides that modulate the action of morphine. Proc Natl Acad Sci USA 82 (1982) 7757-7761
    • (1982) Proc Natl Acad Sci USA , vol.82 , pp. 7757-7761
    • Yang, H.-Y.T.1    Fratta, W.2    Majane, E.A.3    Costa, E.4
  • 54
    • 0020647061 scopus 로고
    • Characterisation and localization of met5-enkephalin-Arg6-Phe7 stored in various rat brain regions
    • Yang H.-Y.T., Panula P., Tang J., and Costa E. Characterisation and localization of met5-enkephalin-Arg6-Phe7 stored in various rat brain regions. J Neurochem 40 (1983) 969-976
    • (1983) J Neurochem , vol.40 , pp. 969-976
    • Yang, H.-Y.T.1    Panula, P.2    Tang, J.3    Costa, E.4
  • 56
    • 0029100398 scopus 로고
    • Opiate receptor changes after chronic exposure to agonists and antagonists
    • Zadina J.E., Kastin A.J., Harrison L.M., Ge L.J., and Chang S.L. Opiate receptor changes after chronic exposure to agonists and antagonists. Ann N Y Acad Sci 757 (1995) 353-361
    • (1995) Ann N Y Acad Sci , vol.757 , pp. 353-361
    • Zadina, J.E.1    Kastin, A.J.2    Harrison, L.M.3    Ge, L.J.4    Chang, S.L.5
  • 57
    • 0036721040 scopus 로고    scopus 로고
    • (-)U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneace tamide] induces internalization and downregulation of the human, but not the rat, kappa-opioid receptor: structural basis for the differential regulation
    • Zhang F., Li J., Li J.G., and Liu-Chen L.Y. (-)U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneace tamide] induces internalization and downregulation of the human, but not the rat, kappa-opioid receptor: structural basis for the differential regulation. J Pharmacol Exp Ther 302 (2002) 1184-1192
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 1184-1192
    • Zhang, F.1    Li, J.2    Li, J.G.3    Liu-Chen, L.Y.4
  • 58
    • 0031978958 scopus 로고    scopus 로고
    • Agonist induced desensitization and downregulation of the human kappa opioid receptor expressed in Chinese hamster ovary cells
    • Zhu J., Luo L.Y., Mao G.F., Ashby B., and Liu-Chen L.Y. Agonist induced desensitization and downregulation of the human kappa opioid receptor expressed in Chinese hamster ovary cells. J Pharmacol Exp Ther 285 (1998) 28-36
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 28-36
    • Zhu, J.1    Luo, L.Y.2    Mao, G.F.3    Ashby, B.4    Liu-Chen, L.Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.