ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists

Atherosclerosis

Volumn 209, Issue 1, 2010, Pages 81-88

  Feingold, Kenneth R ^a,b   Kazemi, Mahmood R ^a,b   Magra, Amy L ^c   McDonald, Carol M ^a,b   Chui, Lisa G ^a,b   Shigenaga, Judy K ^a,b   Patzek, Sophie M ^a,b   Chan, Zoe W ^a,b   Londos, Constantine ^c   Grunfeld, Carl ^a,b  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Acute phase response; Atherosclerosis; Endotoxin; Foam cell; Zymosan

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; ADIPOPHILIN; CHOLESTEROL ESTER; FAT DROPLET; FATTY ACID; FATTY ACID BINDING PROTEIN; GAMMA INTERFERON; IMIQUIMOD; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTRALIPID; LIPOPOLYSACCHARIDE; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR AGONIST; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ZYMOSAN;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; FOAM CELL; GENE INDUCTION; MACROPHAGE; MACROPHAGE ACTIVATION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINOQUINOLINES; ANIMALS; ATHEROSCLEROSIS; CHOLESTEROL ESTERS; FATTY ACID-BINDING PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MEMBRANE PROTEINS; MICE; NEOPLASM PROTEINS; POLY I-C; TOLL-LIKE RECEPTORS; TRIGLYCERIDES; ZYMOSAN;

EID: 77049103329     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.08.042     Document Type: Article

References (45)

1. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 340 (1999) 115-126
2. Epstein S.E., Zhu J., Burnett M.S., Zhou Y.F., Vercellotti G., and Hajjar D. Infection and atherosclerosis: potential roles of pathogen burden and molecular mimicry. Arterioscler Thromb Vasc Biol 20 (2000) 1417-1420
3. Kalayoglu M.V., Libby P., and Byrne G.I. Chlamydia pneumoniae as an emerging risk factor in cardiovascular disease. JAMA 288 (2002) 2724-2731
4. Laberge M.A., Moore K.J., and Freeman M.W. Atherosclerosis and innate immune signalling. Ann Med 37 (2005) 130-140
5. Pussinen P.J., and Mattila K. Periodontal infections and atherosclerosis: mere associations?. Curr Opin Lipidol 15 (2004) 583-588
6. Rock F.L., Hardiman G., Timans J.C., Kastelein R.A., and Bazan J.F. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci U S A 95 (1998) 588-593
7. Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature 430 (2004) 257-263
8. Tobias P., and Curtiss L.K. Thematic review series: the immune system and atherogenesis. Paying the price for pathogen protection: toll receptors in atherogenesis. J Lipid Res 46 (2005) 404-411
9. Kiechl S., Lorenz E., Reindl M., et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 347 (2002) 185-192
10. Pussinen P.J., Vilkuna-Rautiainen T., Alfthan G., et al. Severe periodontitis enhances macrophage activation via increased serum lipopolysaccharide. Arterioscler Thromb Vasc Biol 24 (2004) 2174-2180
11. Ohashi K., Burkart V., Flohe S., and Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 164 (2000) 558-561
12. Shi H., Kokoeva M.V., Inouye K., Tzameli I., Yin H., and Flier J.S. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116 (2006) 3015-3025
13. Miller Y.I., Chang M.K., Binder C.J., Shaw P.X., and Witztum J.L. Oxidized low density lipoprotein and innate immune receptors. Curr Opin Lipidol 14 (2003) 437-445
14. Xu X.H., Shah P.K., Faure E., et al. Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation 104 (2001) 3103-3108
15. Oiknine J., and Aviram M. Increased susceptibility to activation and increased uptake of low density lipoprotein by cholesterol-loaded macrophages. Arterioscler Thromb 12 (1992) 745-753
16. Funk J.L., Feingold K.R., Moser A.H., and Grunfeld C. Lipopolysaccharide stimulation of RAW 264.7 macrophages induces lipid accumulation and foam cell formation. Atherosclerosis 98 (1993) 67-82
17. Ostos M.A., Recalde D., Zakin M.M., and Scott-Algara D. Implication of natural killer T cells in atherosclerosis development during a LPS-induced chronic inflammation. FEBS Lett 519 (2002) 23-29
18. Lehr H.A., Sagban T.A., Ihling C., et al. Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet. Circulation 104 (2001) 914-920
19. Brasaemle D.L., Barber T., Wolins N.E., Serrero G., Blanchette-Mackie E.J., and Londos C. Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 38 (1997) 2249-2263
20. Magra A.L., Mertz P.S., Torday J.S., and Londos C. Role of adipose differentiation-related protein in lung surfactant production: a reassessment. J Lipid Res 47 (2006) 2367-2373
21. Robenek H., Robenek M.J., Buers I., et al. Lipid droplets gain PAT family proteins by interaction with specialized plasma membrane domains. J Biol Chem 280 (2005) 26330-26338
22. Robenek H., Robenek M.J., and Troyer D. PAT family proteins pervade lipid droplet cores. J Lipid Res 46 (2005) 1331-1338
23. Wolins N.E., Quaynor B.K., Skinner J.R., Schoenfish M.J., Tzekov A., and Bickel P.E. S3-12, adipophilin, and TIP47 package lipid in adipocytes. J Biol Chem 280 (2005) 19146-19155
24. Llorente-Cortes V., Royo T., Juan-Babot O., and Badimon L. Adipocyte differentiation-related protein is induced by LRP1-mediated aggregated LDL internalization in human vascular smooth muscle cells and macrophages. J Lipid Res 48 (2007) 2133-2140
25. Larigauderie G., Furman C., Jaye M., et al. Adipophilin enhances lipid accumulation and prevents lipid efflux from THP-1 macrophages: potential role in atherogenesis. Arterioscler Thromb Vasc Biol 24 (2004) 504-510
26. Boord J.B., Fazio S., and Linton M.F. Cytoplasmic fatty acid-binding proteins: emerging roles in metabolism and atherosclerosis. Curr Opin Lipidol 13 (2002) 141-147
27. Kazemi M.R., McDonald C.M., Shigenaga J.K., Grunfeld C., and Feingold K.R. Adipocyte fatty acid-binding protein expression and lipid accumulation are increased during activation of murine macrophages by toll-like receptor agonists. Arterioscler Thromb Vasc Biol 25 (2005) 1220-1224
28. Krieg P., Feil S., Furstenberger G., and Bowden G.T. Tumor-specific overexpression of a novel keratinocyte lipid-binding protein. Identification and characterization of a cloned sequence activated during multistage carcinogenesis in mouse skin. J Biol Chem 268 (1993) 17362-17369
29. Makowski L., Boord J.B., Maeda K., et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med 7 (2001) 699-705
30. Hertzel A.V., and Bernlohr D.A. The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function. Trends Endocrinol Metab 11 (2000) 175-180
31. Scheja L., Makowski L., Uysal K.T., et al. Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice. Diabetes 48 (1999) 1987-1994
32. Boord J.B., Maeda K., Makowski L., et al. Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice. Circulation 110 (2004) 1492-1498
33. Guha M., and Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 13 (2001) 85-94
34. Zhang G., and Ghosh S. Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors. J Endotoxin Res 6 (2000) 453-457
35. Vlahos C.J., Matter W.F., Hui K.Y., and Brown R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269 (1994) 5241-5248
36. Cuenda A., Rouse J., Doza Y.N., et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 364 (1995) 229-233
37. Alessi D.R., Cuenda A., Cohen P., Dudley D.T., and Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270 (1995) 27489-27494
38. Noman A.S., Koide N., Hassan F., et al. Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression. Innate Immun 15 (2009) 33-41
39. Gay N.J., and Gangloff M. Structure and function of Toll receptors and their ligands. Annu Rev Biochem 76 (2007) 141-165
40. Gu J.Q., Ikuyama S., Wei P., et al. Pycnogenol, an extract from French maritime pine, suppresses Toll-like receptor 4-mediated expression of adipose differentiation-related protein in macrophages. Am J Physiol Endocrinol Metab 295 (2008) E1390-E1400
41. Werb Z., and Chin J.R. Endotoxin suppresses expression of apoprotein E by mouse macrophages in vivo and in culture. A biochemical and genetic study. J Biol Chem 258 (1983) 10642-10648
42. Baranova I., Vishnyakova T., Bocharov A., et al. Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells. Infect Immun 70 (2002) 2995-3003
43. Khovidhunkit W., Moser A.H., Shigenaga J.K., Grunfeld C., and Feingold K.R. Regulation of scavenger receptor class B type I in hamster liver and Hep3B cells by endotoxin and cytokines. J Lipid Res 42 (2001) 1636-1644
44. Khovidhunkit W., Moser A.H., Shigenaga J.K., Grunfeld C., and Feingold K.R. Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR. J Lipid Res 44 (2003) 1728-1736
45. Blessing E., Kuo C.C., Lin T.M., et al. Foam cell formation inhibits growth of Chlamydia pneumoniae but does not attenuate Chlamydia pneumoniae-induced secretion of proinflammatory cytokines. Circulation 105 (2002) 1976-1982