Site-specific and stoichiometric conjugation of cationic porphyrins to antiangiogenic monoclonal antibodies

Bioconjugate Chemistry

Volumn 21, Issue 2, 2010, Pages 302-312

  Alonso, Cristina M A ^a   Palumbo, Alessandro ^b   Bullous, Aaron J ^a   Pretto, Francesca ^b   Neri, Dario ^b   Boyle, Ross W ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HYDROPHILICITY; MONOCLONAL ANTIBODIES; SURFACE PLASMON RESONANCE;

ANTIANGIOGENIC; CATIONIC PORPHYRIN; CATIONICS; CYSTEINE RESIDUES; MALEIMIDES; PHOTOCYTOTOXICITY; PORPHYRIN DERIVATIVES; SELECTIVE REACTIVITY; SITE-SPECIFIC; SPECIFIC CONJUGATIONS;

PORPHYRINS;

AMINE; ANGIOGENESIS INHIBITOR; ANTIBODY CONJUGATE; CATION; CYSTEINE; IMMUNOGLOBULIN; MALEIMIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY L19; PORPHYRIN; THIOL; UNCLASSIFIED DRUG;

ARTICLE; CONJUGATION; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROPHILICITY; IMMUNOREACTIVITY; IN VITRO STUDY; MOLECULAR CLONING; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PROTEIN EXPRESSION; STOICHIOMETRY;

EID: 77049102226     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc9003537     Document Type: Article

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