Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: Distinct responses to stimuli

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 26, Issue 5, 2006, Pages 1058-1065

  Deng, David Xing Fei ^a   Spin, Joshua M ^b   Tsalenko, Anya ^a   Vailaya, Aditya ^a   Ben Dor, Amir ^a   Yakhini, Zohar ^a   Tsao, Phil ^b   Brunn, Laurakay ^a   Quertermous, Thomas ^b  

^a AGILENT LABORATORIES   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coronary arteries; Gene expression profiling; Saphenous vein; Smooth muscle cells

Indexed keywords

BETA CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; METALLOPROTEINASE INHIBITOR; OXIDIZED LOW DENSITY LIPOPROTEIN; PROSTAGLANDIN RECEPTOR; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; CELL CYCLE PROTEIN; COLLAGEN; CYTOKINE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN; NUCLEAR PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; RCC1 PROTEIN, HUMAN; SOMATOMEDIN BINDING PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CORONARY ARTERY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HYPERLIPIDEMIA; IMMUNOCOMPETENT CELL; LIPID METABOLISM; MARKER GENE; MOLECULAR MECHANICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RESTENOSIS; SAPHENOUS VEIN; SMOOTH MUSCLE FIBER; STIMULUS RESPONSE; VASCULAR SMOOTH MUSCLE; VEIN GRAFT; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CORONARY BLOOD VESSEL; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ATHEROSCLEROSIS; CELL CYCLE PROTEINS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; CORONARY VESSELS; CYTOKINES; GENE EXPRESSION REGULATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; LIPOPROTEINS, LDL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; NUCLEAR PROTEINS; PHENOTYPE; PLATELET-DERIVED GROWTH FACTOR; SAPHENOUS VEIN;

EID: 33646452284     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000208185.16371.97     Document Type: Article

References (21)

1. Manabe I, Owens GK. The smooth muscle myosin heavy chain gene exhibits smooth muscle subtype-selective modular regulation in vivo. J Biol Chem. 2001;276:39076-39087.
2. Fujita H, Shimokado K, Yutani C, Takaichi S, Masuda J, Ogata J. Human neonatal and adult vascular smooth muscle cells in culture. Exp Mol Pathol 1993;58:25-39.
3. Yang Z, Oemar BS, Carrel T, Kipfer B, Julmy F, Luscher TF. Different proliferative properties of smooth muscle cells of human arterial and venous bypass vessels: role of PDGF receptors, mitogen-activated protein kinase, and cyclin-dependent kinase inhibitors. Circulation. 1998;97:181-187.
4. Liu B, Itoh H, Louie O, Kubota K, Kent KC. The role of phospholipase C and phosphatidylinositol 3-kinase in vascular smooth muscle cell migration and proliferation. J Surg Res. 2004;120:256-265.
5. Motwani JG, Topol EJ. Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, and prevention. Circulation. 1998;97:916-931.
6. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med. 1999;340:115-126.
7. Libby P. Inflammation in atherosclerosis. Nature. 2002;420:868-874.
8. Deng D, Tsalenko A, Vailaya A, Ben-Dor A, Estay I, Tabibiazar R, Kincaid R, Yakhini Z, Bruhn L, Quertermous T. Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli. Circ Res. 2006;98:200-208.
9. Ho M, Yang E, Matcuk G, Deng D, Sampas N, Tsalenko A, Tabibiazar R, Zhang Y, Chen M, Talbi S, Ho YD, Wang J, Tsao PS, Ben-Dor A, Yakhini Z, Bruhn L, Quertermous T. Identification of endothelial cell genes by combined database mining and microarray analysis. Physiol Genomics. 2003;13:249-262.
10. Robbesyn F, Salvayre R, Negre-Salvayre A. Dual role of oxidized LDL on the NF-kappaB signaling pathway. Free Radic Res. 2004;38:541-551.
11. Bjorkerud B, Bjorkerud S. Contrary effects of lightly and strongly oxidized LDL with potent promotion of growth versus apoptosis on arterial smooth muscle cells, macrophages, and fibroblasts. Arterioscler Thromb Vasc Biol 1996;16:416-424.
12. Scheidegger KJ, James RW, Delafontaine P. Differential effects of low density lipoproteins on insulin-like growth factor-1 (IGF-1) and IGF-1 receptor expression in vascular smooth muscle cells. J Biol Chem. 2000;275:26864-26869.
13. Delafontaine P, Song YH, Li Y. Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. Arterioscler Thromb Vasc Biol 2004;24:435-444.
14. Grant MB, Wargovich TJ, Ellis EA, Tarnuzzer R, Caballero S, Estes K, Rossing M, Spoerri PE, Pepine C. Expression of IGF-I, IGF-I receptor and IGF binding proteins-1, -2, -3, -4 and -5 in human atherectomy specimens. Regul Pept. 1996;67:137-144.
15. Zhang QJ, Goddard M, Shanahan C, Shapiro L, Bennett M. Differential gene expression in vascular smooth muscle cells in primary atherosclerosis and in stent stenosis in humans. Arterioscler Thromb Vasc Biol. 2002;22:2030-2036.
16. Zettler ME, Prociuk MA, Austria JA, Zhong G, Pierce GN. Oxidized low-density lipoprotein retards the growth of proliferating cells by inhibiting nuclear translocation of cell cycle proteins. Arterioscler Thromb Vasc Biol. 2004;24:727-732.
17. Holm T, Damas JK, Holven K, Nordoy I, Brosstad FR, Ueland T, Wahre T, Kjekshus J, Froland SS, Eiken HG, Solum NO, Gullestad L, Nenseter M, Aukrust P. CXC-chemokines in coronary artery disease: possible pathogenic role of interactions between oxidized low-density lipoprotein, platelets and peripheral blood mononuclear cells. J Thromb Haemost. 2003;1:257-262.
18. Shin WS, Szuba A, Rockson SG. The role of chemokines in human cardiovascular pathology: enhanced biological insights. Atherosclerosis. 2002;160:91-102.
19. Kumar MS, Owens GK. Combinatorial control of smooth muscle-specific gene expression. Arterioscler Thromb Vasc Biol. 2003;23:737-747.
20. Haug C, Schmid-Kotsas A, Zorn U, Bachem MG, Schuett S, Gruenert A, Rozdzinski E. Hepatocyte growth factor is upregulated by low-density lipoproteins and inhibits endothelin-1 release. Am J Physiol Heart Circ Physiol 2000;279:H2865-H2871.
21. Haug C, Schmid-Kotsas A, Zorn U, Schuett S, Gross HJ, Gruenert A, Bachern MG. Endothelin-1 synthesis and endothelin B receptor expression in human coronary artery smooth muscle cells and monocyte-derived macrophages is up-regulated by low density lipoproteins. J Mol Cell Cardiol. 2001;33:1701-1712.