Daedalea gibbosasubstances inhibit LPS-induced expression of iNOS by suppression of NF-γB and MAPK activities in RAW 264.7 macrophage cells

International Journal of Molecular Medicine

Volumn 25, Issue 3, 2010, Pages 421-432

  Ruimi, Nili ^a,b   Rwashdeh, Haithem ^a   Wasser, Solomon ^b   Konkimalla, Badireenath ^c   Efferth, Thomas ^c   Bprgatti, Monica ^d   Gambari, Roberto ^d   Mahajna, Jamal ^a  

^a Cancer Drug Discovery Program   (Italy)

^b UNIVERSITY OF HAIFA   (Israel)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF FERRARA   (Italy)

Author keywords

I B phosphorylation; IiNOS expression; MAPK; NF B activation pathway

Indexed keywords

CURCUMIN; DAEDALEA GIBBOSA EXTRACT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL PRODUCT; NITRIC OXIDE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; GENE EXPRESSION; GENE EXPRESSION PROFILING; MACROPHAGE; MUSHROOM; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN DNA BINDING; TRANSCRIPTION REGULATION; AGARICALES; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MICROARRAY ANALYSIS; MOUSE; PROMOTER REGION;

AGARICALES; ANIMALS; CELL LINE; DINOPROSTONE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICROARRAY ANALYSIS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS, GENETIC;

EID: 76949105676     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000361     Document Type: Article

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