Preclinical safety validation of a stabilized viral vector direct injection approach to the cervical spinal cord

Clinical and Translational Science

Volumn 2, Issue 2, 2009, Pages 165-167

  Federici, Thais ^a   Riley, Jonathan ^b   Park, John ^c   Bain, Mark ^c   Boulis, Nicholas M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Adeno associatedviral vector; Cervical spinal cord; Gene therapy; Pig; Targeted delivery

Indexed keywords

GREEN FLUORESCENT PROTEIN; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSAFETY; CERVICAL SPINAL CORD; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; FEMALE; MICROINJECTION; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SPINAL CORD VENTRAL HORN; SWINE; VALIDATION STUDY; VIRAL GENE DELIVERY SYSTEM; ANIMAL; ANIMAL BEHAVIOR; ANTERIOR HORN CELL; CERVICAL SPINE; CYTOLOGY; DEPENDOPARVOVIRUS; GENE TRANSFER; GENE VECTOR; GENETICS; INTRASPINAL DRUG ADMINISTRATION; METABOLISM;

SUIDAE;

ANIMALS; ANTERIOR HORN CELLS; BEHAVIOR, ANIMAL; CERVICAL VERTEBRAE; DEPENDOVIRUS; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; INJECTIONS, SPINAL; MICROINJECTIONS; SUS SCROFA;

EID: 76949104119     PISSN: 17528054     EISSN: 17528062     Source Type: Journal    
DOI: 10.1111/j.1752-8062.2008.00084.x     Document Type: Article

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