Cervical spinal cord therapeutics delivery: Preclinical safety validation of a stabilized microinjection platform

Neurosurgery

Volumn 65, Issue 4, 2009, Pages 754-761

  Riley, Jonathan ^a   Federici, Thais ^b   Park, John ^c   Suzuki, Masatoshi ^d   Franz, Colin K ^b   Tork, Craig ^d   McHugh, Jacalyn ^d   Teng, Qingshan ^c   Svendsen, Clive ^d   Boulis, Nicholas M ^b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cell therapy; Cervical spinal cord; Microinjection; Neural progenitor cells; Pigs

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN A;

ACCURACY; ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CANNULA; CERVICAL SPINAL CORD; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; EPIDURAL HEMATOMA; FARM ANIMAL; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; LAMINECTOMY; MICROINJECTION; MINIPIG; MORBIDITY; NONHUMAN; PEROPERATIVE CARE; POSTOPERATIVE CARE; PRIORITY JOURNAL; SAFETY; SPINAL CORD INJURY; SPINAL CORD VENTRAL HORN; STEM CELL; STEM CELL TRANSPLANTATION; SWINE; VALIDATION STUDY;

ANIMALS; ANTERIOR HORN CELLS; CELL DIFFERENTIATION; CELL SURVIVAL; CERVICAL VERTEBRAE; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HEMATOMA, EPIDURAL, SPINAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFUSION PUMPS; LAMINECTOMY; MICROINJECTIONS; NEUROGENESIS; POSTOPERATIVE COMPLICATIONS; SPINAL CORD; SPINAL CORD DISEASES; STEM CELL TRANSPLANTATION; STEM CELLS; STEREOTAXIC TECHNIQUES; SUS SCROFA; SYRINGES; TRANSPLANTATION, HETEROLOGOUS; TREATMENT OUTCOME;

EID: 70349730271     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000343524.45387.9E     Document Type: Article

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