Relaxation by Β3-adrenoceptor agonists of the isolated human internal anal sphincter

Life Sciences

Volumn 86, Issue 9-10, 2010, Pages 358-364

  Ballester, Cristina ^a   Sarriá, Benjamín ^a   García Granero, Eduardo ^a,b   Mata, Manuel ^c,d   Milara, Javier ^c   Morcillo, Esteban J ^a,b,d   Lledó, Salvador ^a,b   Cortijo, Julio ^a,c  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^c HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

3 Adrenoceptor; Anorectal hypertonicity; Cyclic AMP; Human; In vitro; Internal anal sphincter; Intracellular calcium

Indexed keywords

1 (2 ETHYLPHENOXY) 3 (1,2,3,4 TETRAHYDRO 1 NAPHTHYLAMINO) 2 PROPANOL OXALATE; 4 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL]PHENOXYACETIC ACID; [[7 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO] 5,6,7,8 TETRAHYDRO 2 NAPHTHYL]OXY]ACETIC ACID ETHYL ESTER; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 3 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ION; CYCLIC AMP; CYCLIC GMP; ISOPRENALINE; NITRIC OXIDE SYNTHASE;

ADULT; AGED; ANUS SPHINCTER; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; ENZYME IMMUNOASSAY; ENZYME INHIBITION; EPIFLUORESCENCE MICROSCOPY; FEMALE; HUMAN; HUMAN TISSUE; IC 50; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; PROTEIN EXPRESSION; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; ADULT; AGED; AGED, 80 AND OVER; ANAL CANAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOLAMINES; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE RELAXATION; RECEPTORS, ADRENERGIC, BETA-3;

EID: 76849097572     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.01.005     Document Type: Article

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