Effects of ouabain on human bronchial muscle in vitro

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 368, Issue 5, 2003, Pages 393-403

  Cortijo, Julio ^a   Sarria, Benjamín ^a   Mata, Manuel ^a   Naline, Emmanuel ^b   Advenier, Charles ^b   Morcillo, Esteban J ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b CENTRE HOSPITALIER DE VERSAILLES   (France)

Author keywords

Airway smooth muscle; Human isolated bronchus; Inositol phosphates; Intracellular free Ca2+ ; Membrane potential; Na+ K + ATPase; Ouabain

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; ALPHA ADRENERGIC RECEPTOR; AMILORIDE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; DILTIAZEM; FORSKOLIN; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; INDOMETACIN; INOSITOL PHOSPHATE; ISOPRENALINE; LEMAKALIM; LIPOXYGENASE INHIBITOR; MUSCARINIC RECEPTOR BLOCKING AGENT; NIFEDIPINE; NITROPRUSSIDE SODIUM; OUABAIN; POTASSIUM; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE C; SODIUM; SODIUM CHANNEL BLOCKING AGENT; SODIUM PROTON EXCHANGE PROTEIN; TETRODOTOXIN; UNINDEXED DRUG; VERAPAMIL; ZILEUTON;

ARTICLE; BRONCHUS MUSCLE; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CULTURE MEDIUM; DEPOLARIZATION; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; EPITHELIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INCUBATION TIME; ISOLATED ORGAN; MICROELECTRODE; MUSCLE CONTRACTILITY; MUSCLE CONTRACTION; MUSCLE RELAXATION; NERVE CELL; RECORDING; SMOOTH MUSCLE FIBER; SODIUM CALCIUM EXCHANGE;

ACETYLCHOLINE; BRONCHI; CALCIUM; CALCIUM CHANNEL BLOCKERS; CROMAKALIM; FORSKOLIN; HISTAMINE; HUMANS; INOSITOL PHOSPHATES; ISOPROTERENOL; MEMBRANE POTENTIALS; MUSCLE RELAXATION; MUSCLE, SMOOTH; NA(+)-K(+)-EXCHANGING ATPASE; NITROPRUSSIDE; OUABAIN; PROTEIN KINASE C; SODIUM-HYDROGEN ANTIPORTER; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; TIME FACTORS; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 0344082852     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0818-0     Document Type: Article

References (33)

1. Agrawal KP, Hyatt RE (1986) Airway response to inhaled ouabain and histamine in conscious guinea pigs. J Appl Physiol 60:2089-2093
2. Benos DJ (1982) Amiloride, a molecular probe of sodium transport in tissues and cells. Am J Physiol 242:C131-C145
3. Black J, Armour C, Shaw J (1984) The effect of alteration in temperature on contractile responses in human airways in vitro. Respir Physiol 57:269-277
4. Bova S, Cargnelli G, Luciani S (1988) Na/Ca exchange and tension development in vascular smooth muscle: effect of amiloride. Br J Pharmacol 93:601-608
5. Chideckel EW, Frost JL, Mike P, Fedan JS (1987) The effect of ouabain on tension in isolated respiratory tract smooth muscle of humans and other species. Br J Pharmacol 92:609-614
6. Chilvers ER, Lynch BJ, Challiss RAJ (1994) Phosphoinositide metabolism in airway smooth muscle. Pharmacol Ther 62:221-245
7. Cortijo J, Villagrasa V, Marti-Cabrera M, Villar V, Moreau J, Advenier C, Morcillo EJ, Small RC (1997) The spasmogenic effects of vanadate in human isolated bronchus. Br J Pharmacol 121:1339-1349
8. Crambert G, Hasler U, Beggah AT, Yu C, Modyanov NN, Horisberger JD, Lelievre L, Geering K (2000) Transport and pharmacological properties of nine different human Na, K-ATPase isozymes. J Biol Chem 275:1976-1986
9. De Wardener HE, Macgregor GA, Clarkson EM, Alaghband-Zadeh J, Bitensky L, Chayen J (1981) Effect of sodium intake on the ability of human plasma to inhibit renal adenosine triphosphatase in vitro. Lancet i:411-412
10. + ATPase) enzyme inhibition. J Allergy Clin Immunol 99:367-373
11. Gerthoffer WT, Murphey KA, Khoyi MA (1988) Inhibition of tracheal smooth muscle contraction and myosin phosphorylation by ryanodine. J Pharmacol Exp Ther 246:585-590
12. 2+-indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
13. Hamlyn JM, Blaustein MP, Bova S, DuCharme DW, Harris DW, Mandel F, Mathews WR, Ludens JH (1991) Identification and characterization of a ouabain-like compound from human plasma. Proc Natl Acad Sci USA 88:6259-6263
14. Hyvelin JM, Martin C, Roux E, Marthan R, Savineau JP (2000) Human isolated bronchial smooth muscle contains functional ryanodine/caffeine- sensitive Ca-release channels. Am J Respir Crit Care Med 162:687-694
15. Iwamoto LM, Gries DM, Nakamura KT (2001) Loop diuretics and in vitro relaxation of human fetal and newborn mouse airways. Pediatr Res 50:273-276
16. Iwamoto LM, Nakamura KT, Wada RK (2003) Immunolocalization of a Na-K-2Cl cotransporter in human tracheobronchial smooth muscle. J Appl Physiol 94:1596-1601
17. 2+ level in guinea-pig aorta. Eur J Pharmacol 224:71-76
18. Janssen LJ, Sims SM (1992) Acetylcholine activates non-selective cation and chloride conductances in canine and guinea-pig tracheal myocytes. J Physiol 453:197-218
19. Knox AJ, Ajao P (1994) The effect of inhibitors of Na/H exchange and Na/Ca exchange on airway smooth muscle contractility. Pulm Pharmacol 7:99-102
20. Knox AJ, Ajao P, Britton JR, Tattersfield AE (1990) Effect of sodium-transport inhibitors on airway smooth muscle contractility in vitro. Clin Sci 79:315-323
21. Marco V, Park CD, Aviado DM (1968) Bronchopulmonary effects of digitalis in the anaesthetized dogs. Dis Chest 54:437-444
22. Marthan R, Martin C, Amédée T, Mironneau J (1989) Calcium channel currents in isolated smooth muscle cells from human bronchus. J Appl Physiol 66:1706-1714
23. 2+ signalling by endothelin receptors in rat and human cultured airway smooth muscle cells. Br J Pharmacol 125:1768-1778
24. + pump and sarcoplasmic reticulum in smooth muscle. Nature 365:657-660
25. Morrison KJ, Vanhoutte PM (1996) Stimulation of sodium pump by vasoactive intestinal peptide in guinea-pig isolated trachea: potential contribution to mechanisms underlying relaxation of smooth muscle. Br J Pharmacol 118:557-562
26. Ortiz JL, Cortijo J, Sanz C, De Diego A, Esplugues J, Morcillo E (1991) Cooling-induced contraction of trachea isolated from normal and sensitized guinea-pigs. Naunyn-Schmiedebergs Arch Pharmacol 343:418-426
27. +-pumping in guinea-pig isolated trachealis: their modulation by the epithelium. Br J Pharmacol 98:343-350
28. Rhoden KJ, Douglas JS (1995) Evidence of Na-K-Cl cotransport in airway smooth muscle. Am J Physiol 268:L551-L557
29. + pump in cultured guinea pig airway smooth muscle by sero-tonin. J Pharmacol Exp Ther 293:107-112
30. Sarria B, Naline E, Cortijo J, Moreau J, Cerda JM, Morcillo EJ, Advenier C (1995) Functional, biochemical and morphological studies on human bronchi after cryopreservation. Br J Pharmacol 116:2569-2574
31. 2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus. Am J Physiol 283:L1125-L1132
32. Souhrada M, Souhrada JF, Cherniack RM (1981) Evidence for a sodium electrogenic pump in airway smooth muscle. J Appl Physiol 51:346-352
33. Yang KXF, Black JL (1995) The involvement of protein kinase C in the contraction of human airway smooth muscle. Eur J Pharmacol 275:283-289