JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter

FEBS Letters

Volumn 584, Issue 5, 2010, Pages 852-858

  Rong, Yuanyuan ^a,b,c   Zhang, Mei ^a   Zhang, Lin ^b,c   Wang, Xing Li ^b,c   Shen, Ying H ^b,c  

^a SHANDONG UNIVERSITY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c TEXAS HEART INSTITUTE   (United States)

Author keywords

ATF 2; Histone deacetylase4 (HDAC4); JNK; p38; Palmitic acid (hexadecanoic acid); Thrombomodulin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; HISTONE DEACETYLASE 4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PALMITIC ACID; STRESS ACTIVATED PROTEIN KINASE; THROMBOMODULIN;

ARTICLE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME BINDING; GENE REPRESSION; GENETIC REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 2; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HUMANS; IMMUNOPRECIPITATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PALMITIC ACID; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THROMBOMODULIN;

EID: 76749168032     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.01.048     Document Type: Article

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