Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach

PLoS Computational Biology

Volumn 6, Issue 1, 2010, Pages

  Klijn, Christiaan ^a,b   Bot, Jan ^b,c   Adams, David J ^d   Reinders, Marcel ^b   Wessels, Lodewyk ^a,b   Jonkers, Jos ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c Netherlands Bioinfomatics Centre   (Netherlands)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; CELL MEMBRANES; DISEASES; DNA; GENOME; T-CELLS; TUMORS;

CANCER DEVELOPMENT; CANCER GENES; COPY-NUMBER ALTERATIONS; CORE NETWORKS; DNA COPY NUMBERS; GENETIC MUTATIONS; GROWTH CONTROL; MALIGNANT TUMORS; MULTISTEPS; TUMORIGENESIS;

GENES;

DNA; IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR; TUMOR PROTEIN;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GENE DOSAGE; GENE IDENTIFICATION; GENE MUTATION; GENOME; HUMAN; HUMAN CELL; HYPOTHESIS; SCORING SYSTEM; T LYMPHOCYTE; TUMOR CELL LINE; TUMOR GENE; CHROMOSOME MAP; COPY NUMBER VARIATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN GENOME; METHODOLOGY; SIGNAL TRANSDUCTION;

CHROMOSOME MAPPING; DNA COPY NUMBER VARIATIONS; DNA, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HUMANS; NEOPLASM PROTEINS; SIGNAL TRANSDUCTION;

EID: 76749141850     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000631     Document Type: Article

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