C1qTNF-related protein-6 mediates fatty acid oxidation via the activation of the AMP-activated protein kinase

FEBS Letters

Volumn 584, Issue 5, 2010, Pages 968-972

  Lee, Wan ^a   Kim, Mi Jin ^a   Park, Eun Ju ^a   Choi, Young Jin ^a   Park, Seung Yoon ^a  

^a Dongguk University College of Medicine   (South Korea)

Author keywords

ACC; AMPK; C1QTNF6; CTRP 6; Fatty acid oxidation; Muscle

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADIPONECTIN; C1QTNF RELATED PROTEIN 6; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; GLUCOSE TRANSPORT; IMMUNOBLOTTING; LIPID METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ACETYL-COA CARBOXYLASE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; FATTY ACIDS; HUMANS; LIPID METABOLISM; MICE; MUSCLE CELLS; OXIDATION-REDUCTION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SIGNAL TRANSDUCTION;

EID: 76749106953     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.01.040     Document Type: Article

References (27)

1. Kishore U., Gaboriaud C., Waters P., Shrive A.K., Greenhough T.J., Reid K.B., Sim R.B., and Arlaud G.J. C1q and tumor necrosis factor superfamily: modularity and versatility. Trends Immunol. 25 (2004) 551-561
2. Schaffler A., Scholmerich J., and Salzberger B. Adipose tissue as an immunological organ: Toll-like receptors, C1q/TNFs and CTRPs. Trends Immunol. 28 (2007) 393-399
3. Lasser G., et al. C1qTNF-related protein-1 (CTRP-1): a vascular wall protein that inhibits collagen-induced platelet aggregation by blocking VWF binding to collagen. Blood 107 (2006) 423-430
4. Jeon J.H., et al. A novel adipokine CTRP1 stimulates aldosterone production. FASEB J. 22 (2008) 1502-1511
5. Wong G.W., Wang J., Hug C., Tsao T.S., and Lodish H.F. A family of Acrp30/adiponectin structural and functional paralogs. Proc. Natl. Acad. Sci. USA 101 (2004) 10302-10307
6. Maeda T., Jikko A., Abe M., Yokohama-Tamaki T., Akiyama H., Furukawa S., Takigawa M., and Wakisaka S. Cartducin, a paralog of Acrp30/adiponectin, is induced during chondrogenic differentiation and promotes proliferation of chondrogenic precursors and chondrocytes. J. Cell Physiol. 206 (2006) 537-544
7. Akiyama H., Furukawa S., Wakisaka S., and Maeda T. CTRP3/cartducin promotes proliferation and migration of endothelial cells. Mol. Cell Biochem. 304 (2007) 243-248
8. Hayward C., et al. Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration. Hum. Mol. Genet. 12 (2003) 2657-2667
9. Ayyagari R., et al. Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation. Invest. Ophthalmol. Vis. Sci. 46 (2005) 3363-3371
10. Wong G.W., Krawczyk S.A., Kitidis-Mitrokostas C., Ge G., Spooner E., Hug C., Gimeno R., and Lodish H.F. Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. FASEB J. 23 (2009) 241-258
11. Hardie D.G., Hawley S.A., and Scott J.W. AMP-activated protein kinase-development of the energy sensor concept. J. Physiol. 574 (2006) 7-15
12. Carling D. The AMP-activated protein kinase cascade - a unifying system for energy control. Trends Biochem. Sci. 29 (2004) 18-24
13. Vavvas D., Apazidis A., Saha A.K., Gamble J., Patel A., Kemp B.E., Witters L.A., and Ruderman N.B. Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle. J. Biol. Chem. 272 (1997) 13255-13261
14. Merrill G.F., Kurth E.J., Hardie D.G., and Winder W.W. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am. J. Physiol. 273 (1997) E1107-E1112
15. Wong G.W., Krawczyk S.A., Kitidis-Mitrokostas C., Revett T., Gimeno R., and Lodish H.F. Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions. Biochem. J. 416 (2008) 161-177
16. Park S.Y., Choi J.H., Ryu H.S., Pak Y.K., Park K.S., Lee H.K., and Lee W. C1q tumor necrosis factor {alpha}-related protein isoform 5 is increased in mitochondrial DNA-depleted myocytes, and activates AMP-activated protein kinase. J. Biol. Chem. (2009)
17. Mao X., et al. APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nat. Cell Biol. 8 (2006) 516-523
18. Winder W.W., and Hardie D.G. AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am. J. Physiol. 277 (1999) E1-E10
19. Ruderman N.B., Saha A.K., Vavvas D., and Witters L.A. Malonyl-CoA, fuel sensing, and insulin resistance. Am. J. Physiol. 276 (1999) E1-E18
20. Yoon M.J., Lee G.Y., Chung J.J., Ahn Y.H., Hong S.H., and Kim J.B. Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha. Diabetes 55 (2006) 2562-2570
21. Yamauchi T., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7 (2001) 941-946
22. Ceddia R.B., Somwar R., Maida A., Fang X., Bikopoulos G., and Sweeney G. Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells. Diabetologia 48 (2005) 132-139
23. Tomas E., Tsao T.S., Saha A.K., Murrey H.E., Zhang C., Itani S.I., Lodish H.F., and Ruderman N.B. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc. Natl. Acad. Sci. USA 99 (2002) 16309-16313
24. Onay-Besikci A., Altarejos J.Y., and Lopaschuk G.D. GAd-globular head domain of adiponectin increases fatty acid oxidation in newborn rabbit hearts. J. Biol. Chem. 279 (2004) 44320-44326
25. Wu X., Motoshima H., Mahadev K., Stalker T.J., Scalia R., and Goldstein B.J. Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes 52 (2003) 1355-1363
26. Yamauchi T., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423 (2003) 762-769
27. Chen M.B., et al. Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics. J. Clin. Endocrinol. Metab. 90 (2005) 3665-3672