Identification of avermectin-high-producing strains by high-throughput screening methods

Applied Microbiology and Biotechnology

Volumn 85, Issue 4, 2010, Pages 1219-1225

  Gao, Hong ^a   Liu, Mei ^a   Zhou, Xianlong ^a   Liu, Jintao ^a,d   Zhuo, Ying ^a,d   Gou, Zhongxuan ^a   Xu, Bing ^e   Zhang, Wenquan ^a   Liu, Xiangyang ^a   Luo, Aiqun ^a   Zheng, Chuansen ^a   Chen, Xiaoping ^c   Zhang, Lixin ^a,b,c  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

^c GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e Hebei Veyong Bio Chemical Co Ltd   (China)

Author keywords

Avermectin; High throughput screening; Miniaturized production; Strain improvement

Indexed keywords

AVERMECTINS; BATCH FERMENTATION; BROAD SPECTRUM; ERLENMEYER FLASKS; GOOD CORRELATIONS; HIGH-THROUGHPUT SCREENING; HOST ORGANISM; MICROPLATES; PRODUCTION STRAIN; SIDE EFFECT; STREPTOMYCES AVERMITILIS; UV ABSORBANCE; YIELD STRAIN;

BOTTLES; FERMENTATION; STRAIN;

THROUGHPUT;

AVERMECTIN;

ANTIBIOTICS; ARTHROPOD; BACTERIUM; BIOTECHNOLOGY; FERMENTATION; IDENTIFICATION METHOD; INDUSTRIAL PRODUCTION; NEMATODE; PARASITE;

ACCURACY; ARTICLE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BATCH FERMENTATION; CONTROLLED STUDY; FERMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; NONHUMAN; REPRODUCIBILITY; ULTRAVIOLET SPECTROSCOPY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FERMENTATION; HIGH-THROUGHPUT SCREENING ASSAYS; INDUSTRIAL MICROBIOLOGY; IVERMECTIN; REPRODUCIBILITY OF RESULTS; STREPTOMYCES; ULTRAVIOLET RAYS;

ARTHROPODA; STREPTOMYCES AVERMITILIS;

EID: 76649128997     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2345-5     Document Type: Article

References (26)

1. HF Askal IH Refaat IA Darwish MA Marzouq 2008 A selective spectrophotometric method for determination of rosoxacin antibiotic using sodium nitroprusside as a chromogenic reagent Spectrochim Acta A Mol Biomol Spectrosc 69 1287 1291 10.1016/j.saa.2007.07.031
2. J Buchs 2001 Introduction to advantages and problems of shaken cultures Biochem Eng J 7 91 98 10.1016/S1369-703X(00)00106-6 1:CAS:528: DC%2BD3MXit1Citrs%3D (Pubitemid 32162694)
3. RW Burg BM Miller EE Baker J Birnbaum SA Currie R Hartman YL Kong RL Monaghan G Olson I Putter JB Tunac H Wallick EO Stapley R Oiwa S Omura 1979 Avermectins, new family of potent anthelmintic agents: producing organism and fermentation Antimicrob Agents Chemother 15 361 367 1:CAS:528:DyaE1MXktlOntro%3D
4. E Curdova V Jechova J Zima Z Vanek 1989 The effect of inorganic phosphate on the production of avermectin in Streptomyces avermitilis J Basic Microbiol 29 341 346 10.1002/jobm.3620290607 1:CAS:528:DyaL1MXmt1yktr8%3D
5. del Cardayré SB (2005) Developments in strain improvement technology: evolutionary engineering of industrial microorganisms through gene, pathway, and genome shuffling. In: Zhang L, Demain AL (eds) Natural products: drug discovery and therapeutics medicines. Humana, Totowa, NJ, pp 33-56
6. LF Dobson CC O'Cleirigh DG O'Shea 2008 The influence of morphology on geldanamycin production in submerged fermentations of Streptomyces hygroscopicus var. geldanus Appl Microbiol Biotechnol 79 859 866 10.1007/s00253-008-1493-3 1:CAS:528:DC%2BD1cXmvFSqtrg%3D
7. CY Du YP Zhang Y Li Z Cao 2007 Novel redox potential-based screening strategy for rapid isolation of Klebsiella pneumoniae mutants with enhanced 1,3-propanediol-producing capability Appl Environ Microbiol 73 4515 4521 10.1128/AEM.02857-06 1:CAS:528:DC%2BD2sXot1egsrc%3D (Pubitemid 47122596)
8. EA du Toit M Rautenbach 2000 A sensitive standardised micro-gel well diffusion assay for the determination of antimicrobial activity J Microbiol Methods 42 159 165 10.1016/S0167-7012(00)00184-6
9. WA Duetz L Ruedi R Hermann K O'Connor J Buchs B Witholt 2000 Methods for intense aeration, growth, storage, and replication of bacterial strains in microtiter plates Appl Environ Microbiol 66 2641 2646 10.1128/AEM.66.6.2641- 2646.2000 1:CAS:528:DC%2BD3cXjvFWnsb0%3D (Pubitemid 30353977)
10. H Gao M Liu JT Liu HQ Dai XL Zhou XY Liu Y Zhuo WQ Zhang L Zhang 2009 Medium optimization for the production of avermectin B1a by Streptomyces avermitilis 14-12A using response surface methodology Bioresour Technol 100 4012 4016 10.1016/j.biortech.2009.03.013 1:CAS:528:DC%2BD1MXmtVelsbk%3D
11. R Hermann M Lehmann J Buchs 2003 Characterization of gas-liquid mass transfer phenomena in microtiter plates Biotechnol Bioeng 81 178 186 10.1002/bit.10456 1:CAS:528:DC%2BD3sXht1WksQ%3D%3D (Pubitemid 36077294)
12. YS Hwang ES Kim S Biro CY Choi 2003 Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains Appl Environ Microbiol 69 1263 1269 10.1128/AEM.69.2.1263-1269.2003 1:CAS:528:DC%2BD3sXhtF2itLc%3D (Pubitemid 36204860)
13. H Ikeda S Omura 1995 Control of avermectin biosynthesis in Streptomyces avermitilis for the selective production of a useful component J Antibiot (Tokyo) 48 549 562 1:CAS:528:DyaK2MXnt1Wqsb0%3D
14. H Ikeda S Omura 1997 Avermectin biosynthesis Chem Rev 97 2591 2610 10.1021/cr960023p 1:CAS:528:DyaK2sXnt1Shtb0%3D
15. K Isett H George W Herber A Amanullah 2007 Twenty-four-well plate miniature bioreactor high-throughput system: assessment for microbial cultivations Biotechnol Bioeng 98 1017 1028 10.1002/bit.21484 1:CAS:528:DC%2BD2sXhtlWitLrI (Pubitemid 350205579)
16. MS Kumar PM Kumar HM Sarnaik AK Sadhukhan 2000 A rapid technique for screening of lovastatin-producing strains of Aspergillus terreus by agar plug and Neurospora crassa bioassay J Microbiol Methods 40 99 104 10.1016/S0167-7012(99)00135-9 1:CAS:528:DC%2BD3cXhtFansbg%3D (Pubitemid 30089563)
17. J Lee Y Hwang S Kim E Kim C Choi 2000 Effect of a global regulatory gene, afsR2, from Streptomyces lividans on avermectin production in Streptomyces avermitilis J Biosci Bioeng 89 606 608 10.1016/S1389-1723(00)80065-1 1:CAS:528:DC%2BD3cXmtFGjtbY%3D (Pubitemid 30497647)
18. R Sams 1993 Chemical assay of avermectins by high performance liquid chromatography with fluorescence detection Vet Parasitol 48 59 66 10.1016/0304-4017(93)90144-C 1:CAS:528:DyaK3sXmtFKmsbc%3D (Pubitemid 223053775)
19. KE Tyo H Zhou GN Stephanopoulos 2006 High-throughput screen for poly-3-hydroxybutyrate in Escherichia coli and Synechocystis sp. strain PCC6803 Appl Environ Microbiol 72 3412 3417 10.1128/AEM.72.5.3412-3417.2006 1:CAS:528:DC%2BD28XkvFWjs7Y%3D (Pubitemid 43727994)
20. ZN Xu WH Shen XY Chen JP Lin PL Cen 2005 A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates Biotechnol Lett 27 1135 1140 10.1007/s10529-005-8463-y 1:CAS:528:DC%2BD2MXpsVClsLc%3D (Pubitemid 41215917)
21. H Yu K Tyo H Alper D Klein-Marcuschamer G Stephanopoulos 2008 A high-throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors Biotechnol Bioeng 101 788 796 10.1002/bit.21947 1:CAS:528:DC%2BD1cXht1Clt7%2FI
22. Zhang L (2005a) Integrated approaches for discovering novel drugs from microbial natural products. In: Zhang L, Demain AL (eds) Natural products: drug discovery and therapeutics medicines. Humana, New Jersey, pp 33-56
23. Zhang L (2005b) Screening for synergistic compounds. PCT Patent WO 2005/051303
24. L Zhang R An J Wang N Sun S Zhang J Hu J Kuai 2005 Exploring novel bioactive compounds from marine microbes Curr Opin Microbiol 11 655 662
25. L Zhang K Yan Y Zhang J Bian C Zheng H Sun Z Chen N Sun Y Song Y Zhuo J You, et al. 2007 High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections PNAS 104 4606 4611 10.1073/pnas.0609370104 1:CAS:528:DC%2BD2sXjsFOrsLc%3D (Pubitemid 47186272)
26. HF Zimmermann GT John H Trauthwein U Dingerdissen K Huthmacher 2003 Rapid evaluation of oxygen and water permeation through microplate sealing tapes Biotechnol Prog 19 1061 1063 10.1021/bp025774t 1:CAS:528:DC%2BD3sXjs1SqsLY%3D (Pubitemid 36715161)