Plasma osteopontin concentrations in preeclampsia - Is there an association with endothelial injury?

Clinical Chemistry and Laboratory Medicine

Volumn 48, Issue 2, 2010, Pages 181-187

  Stenczer, Balázs ^a   Rigó Jr , János ^a   Prohászka, Zoltán ^b,c   Derzsy, Zoltán ^a   Lázár, Levente ^a   Makó, Veronika ^b   Cervenak, László ^c   Balogh, Krisztián ^d   Mézes, Miklós ^d   Karádi, István ^b   Molvarec, Attila ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d SZENT ISTVÁN UNIVERSITY   (Hungary)

Author keywords

Endothelial injury; Fibronectin; Osteopontin; Preeclampsia; Pregnancy

Indexed keywords

C REACTIVE PROTEIN; CELL DNA; FIBRONECTIN; MALONALDEHYDE; OSTEOPONTIN; TESTIS DETERMINING FACTOR; THIOBARBITURIC ACID; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; AUTOANALYZER; BIRTH WEIGHT; CASE CONTROL STUDY; CLINICAL ARTICLE; COLORIMETRY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENDOTHELIUM INJURY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS; GESTATIONAL AGE; HUMAN; INFLAMMATION; INTRAUTERINE GROWTH RETARDATION; MATERNAL PLASMA; NEPHELOMETRY; OSTEOPONTIN BLOOD LEVEL; OXIDATIVE STRESS; PREECLAMPSIA; PREGNANT WOMAN; PRIMIPARA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEINURIA; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; TROPHOBLAST;

ADULT; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; DNA; ENDOTHELIUM, VASCULAR; FEMALE; FIBRONECTINS; HUMANS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; INFLAMMATION; MALONDIALDEHYDE; OSTEOPONTIN; OXIDATIVE STRESS; PRE-ECLAMPSIA; PREGNANCY; PRENATAL DIAGNOSIS; RISK FACTORS; TROPHOBLASTS;

EID: 76649125537     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2010.042     Document Type: Article

References (57)

1. Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. Br Med J 2005;330:565.
2. Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999;180:499-506.
3. Saito S, Sakai M. Th1/Th2 balance in preeclampsia. J Reprod Immunol 2003;59:161-173
4. Roberts JM, Gammill HS. Preeclampsia: recent insights. Hypertension 2005;46:1243-1249
5. Molvarec A, Jermendy A, Nagy B, Kovacs M, Varkonyi T, Hupuczi P, et al. Association between tumor necrosis factor (TNF)-alpha G-308A gene polymorphism and preeclampsia complicated by severe fetal growth restriction. Clin Chim Acta 2008;392:52-57
6. Rosta K, Molvarec A, Enzsoly A, Nagy B, Ronai Z, Fekete A, et al. Association of extracellular superoxide dismutase (SOD3) Ala40Thr gene polymorphism with pre-eclampsia complicated by severe fetal growth restriction. Eur J Obstet Gynecol Reprod Biol 2009;142:134-138
7. Nagy B, Varkonyi T, Molvarec A, Lazar L, Hupuczi P, Gabor Than N, et al. Leptin gene (TTTC)(n) microsatellite polymorphism in pre-eclampsia and HELLP syndrome. Clin Chem Lab Med 2009;47:1033-1037
8. Jaaskelainen E, Toivonen S, Keski-Nisula L, Paattiniemi EL, Helisalmi S, Punnonen K, et al. CTLA-4 polymorphism 49AG is associated with placental abruption and preeclampsia in Finnish women. Clin Chem Lab Med 2008;46:169-173
9. Zhang J, Bai H, Liu X, Fan P, Liu R, Huang Y, et al. Genotype distribution of estrogen receptor alpha polymorphisms in pregnant women from healthy and preeclampsia populations and its relation to blood pressure levels. Clin Chem Lab Med 2009;47: 391-397
10. Apparao KB, Murray MJ, Fritz MA, Meyer WR, Chambers AF, Truong PR, et al. Osteopontin and its receptor alphavbeta( 3) integrin are coexpressed in the human endometrium during the menstrual cycle but regulated differentially. J Clin Endocrinol Metab 2001;86:4991-5000.
11. Johnson GA, Burghardt RC, Joyce MM, Spencer TE, Bazer FW, Pfarrer C, et al. Osteopontin expression in uterine stroma indicates a decidualization-like differentiation during ovine pregnancy. Biol Reprod 2003;68:1951-1958
12. Briese J, Oberndorfer M, Patschenik C, Schulte HM, Makrigiannakis A, Loning T, et al. Osteopontin is colocalized with the adhesion molecule CEACAM1 in the extravillous trophoblast of the human placenta and enhances invasion of CEACAM1- expressing placental cells. J Clin Endocrinol Metab 2005;90:5407-5413
13. O'Brien ER, Garvin MR, Stewart DK, Hinohara T, Simpson JB, Schwartz SM, et al. Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb 1994;14:1648-1656
14. Wang KX, Denhardt DT. Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev 2008; 19:333-345
15. Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, et al. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 2000; 287:860-864
16. Johnson GA, Burghardt RC, Bazer FW, Spencer TE. Osteopontin: roles in implantation and placentation. Biol Reprod 2003;69:1458-1471
17. Scatena M, Liaw L, Giachelli CM. Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease. Arterioscler Thromb Vasc Biol 2007;27:2302-2309
18. Wong CK, Lit LC, Tam LS, Li EK, Lam CW. Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus. Rheumatology (Oxford) 2005;44:602-606
19. Comabella M, Pericot I, Goertsches R, Nos C, Castillo M, Blas Navarro J, et al. Plasma osteopontin levels in multiple sclerosis. J Neuroimmunol 2005;158:231-239
20. Mishima R, Takeshima F, Sawai T, Ohba K, Ohnita K, Isomoto H, et al. High plasma osteopontin levels in patients with inflammatory bowel disease. J Clin Gastroenterol 2007;41:167-172
21. Mohler ER 3rd, Adam LP, McClelland P, Graham L, Hathaway DR. Detection of osteopontin in calcified human aortic valves. Arterioscler Thromb Vasc Biol 1997;17:547-552
22. Ohmori R, Momiyama Y, Taniguchi H, Takahashi R, Kusuhara M, Nakamura H, et al. Plasma osteopontin levels are associated with the presence and extent of coronary artery disease. Atherosclerosis 2003;170:333-337
23. Georgiadou P, Iliodromitis EK, Varounis C, Mavroidis M, Kolokathis F, Andreadou I, et al. Relationship between plasma osteopontin and oxidative stress in patients with coronary artery disease. Expert Opin Ther Targets 2008;12:917-920
24. Kurata M, Okura T, Watanabe S, Fukuoka T, Higaki J. Osteopontin and carotid atherosclerosis in patients with essential hypertension. Clin Sci (Lond) 2006;111:319-324
25. Giachelli CM, Bae N, Almeida M, Denhardt DT, Alpers CE, Schwartz SM. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest 1993;92:1686-1696
26. Roberts JM, Gammill H. Pre-eclampsia and cardiovascular disease in later life. Lancet 2005;366:961-962
27. Paternoster DM, Fantinato S, Stella A, Nanhorngue KN, Milani M, Plebani M, et al. C-reactive protein in hypertensive disorders in pregnancy. Clin Appl Thromb Hemost 2006;12:330-337
28. Molvarec A, Kalabay L, Derzsy Z, Szarka A, Halmos A, Stenczer B, et al. Preeclampsia is associated with decreased serum alpha(2)-HS glycoprotein (fetuin-A) concentration. Hypertens Res 2009;32:665-669
29. Molvarec A, Rigo J Jr, Boze T, Derzsy Z, Cervenak L, Mako V, et al. Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. Thromb Haemost 2009;101:305-311
30. Stubbs TM, Lazarchick J, Horger EO 3rd. Plasma fibronectin levels in preeclampsia: a possible biochemical marker for vascular endothelial damage. Am J Obstet Gynecol 1984;150: 885-887
31. Paternoster D, Stella A, Simioni P, Trovo S, Plebani P, Girolami A. Clotting inhibitors and fibronectin as potential markers in preeclampsia. Int J Gynaecol Obstet 1994;47:215-221
32. Paternoster DM, Stella A, Simioni P, Girolami A, Plebani M. Fibronectin and antithrombin as markers of pre-eclampsia in pregnancy. Eur J Obstet Gynecol Reprod Biol 1996;70:33-39
33. Aydin S, Benian A, Madazli R, Uludag S, Uzun H, Kaya S. Plasma malondialdehyde, superoxide dismutase, sE-selectin, fibronectin, endothelin-1 and nitric oxide levels in women with preeclampsia. Eur J Obstet Gynecol Reprod Biol 2004;113: 21-25
34. Ostlund E, Hansson LO, Bremme K. Fibronectin is a marker for organ involvement and may reflect the severity of preeclampsia. Hypertens Pregnancy 2001;20:79-87.
35. Paternoster DM, Stella A, Simioni P, Mussap M, Plebani M. Coagulation and plasma fibronectin parameters in HELLP syndrome. Int J Gynaecol Obstet 1995;50:263-268
36. Leeflang MM, Cnossen JS, van der Post JA, Mol BW, Khan KS, ter Riet G. Accuracy of fibronectin tests for the prediction of pre-eclampsia: a systematic review. Eur J Obstet Gynecol Reprod Biol 2007;133:12-19
37. Paternoster DM, Stella A, Mussap M, Plebani M, Gambaro G, Grella PV. Predictive markers of pre-eclampsia in hypertensive disorders of pregnancy. Int J Gynaecol Obstet 1999;66:237-243
38. Uotila JT, Tuimala RJ, Aarnio TM, Pyykko KA, Ahotupa MO. Findings on lipid peroxidation and antioxidant function in hypertensive complications of pregnancy. Br J Obstet Gynaecol 1993;100:270-276
39. Gupta S, Agarwal A, Sharma RK. The role of placental oxidative stress and lipid peroxidation in preeclampsia. Obstet Gynecol Surv 2005;60:807-816
40. Padmini E, Lavanya S, Uthra V. Preeclamptic placental stress and over expression of mitochondrial HSP70. Clin Chem Lab Med 2009;47:1073-1080
41. Zhong XY, Holzgreve W, Hahn S. The levels of circulatory cell free fetal DNA in maternal plasma are elevated prior to the onset of preeclampsia. Hypertens Pregnancy 2002;21:77-83.
42. Lo YM, Leung TN, Tein MS, Sargent IL, Zhang J, Lau TK, et al. Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia. Clin Chem 1999;45:184-188
43. Molvarec A, Rigo J Jr, Lazar L, Balogh K, Mako V, Cervenak L, et al. Increased serum heat-shock protein 70 levels reflect systemic inflammation, oxidative stress and hepatocellular injury in preeclampsia. Cell Stress Chaperones 2009;14:151-159
44. Molvarec A, Derzsy Z, Kocsis J, Boze T, Nagy B, Balogh K, et al. Circulating anti-heat-shock-protein antibodies in normal pregnancy and preeclampsia. Cell Stress Chaperones 2009;14: 491-498
45. Joubert K. Standards of the body mass and body length of birth in Hungary on the basis of the 1990-1996 nation-wide liveborn data. Magy Noorv L 2000;63:155-163
46. Placer ZA, Cushman LL, Johnson BC. Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems. Anal Biochem 1966;16:359-364
47. Lazar L, Nagy B, Ban Z, Nagy GR, Papp Z. Presence of cellfree fetal DNA in plasma of women with ectopic pregnancies. Clin Chem 2006;52:1599-1601
48. Coskun S, Atalar E, Ozturk E, Yavuz B, Ozer N, Goker H, et al. Plasma osteopontin levels are elevated in non-ST-segment elevation acute coronary syndromes. J Natl Med Assoc 2006; 98:1746-1750
49. Soejima H, Irie A, Fukunaga T, Oe Y, Kojima S, Kaikita K, et al. Osteopontin expression of circulating T cells and plasma osteopontin levels are increased in relation to severity of heart failure. Circ J 2007;71:1879-1884
50. Fitzpatrick LA, Severson A, Edwards WD, Ingram RT. Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis. J Clin Invest 1994;94:1597-1604
51. Cho HJ, Cho HJ, Kim HS. Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification. Curr Atheroscler Rep 2009;11:206-213
52. Saito S, Umekage H, Sakamoto Y, Sakai M, Tanebe K, Sasaki Y, et al. Increased T-helper-1-type immunity and decreased Thelper- 2-type immunity in patients with preeclampsia. Am J Reprod Immunol 1999;41:297-306.
53. Gabinskaya T, Salafia CM, Gulle VE, Holzman IR, Weintraub AS. Gestational age-dependent extravillous cytotrophoblast osteopontin immunolocalization differentiates between normal and preeclamptic pregnancies. Am J Reprod Immunol 1998;40: 339-346
54. Schmidt M, Hoffmann B, Beelen D, Gellhaus A, Winterhager E, Kimmig R, et al. Detection of circulating trophoblast particles in peripheral maternal blood in preeclampsia complicated pregnancies. Hypertens Pregnancy 2008;27:131-142
55. Beninati S, Senger DR, Cordella-Miele E, Mukherjee AB, Chackalaparampil I, Shanmugam V, et al. Osteopontin: its transglutaminase-catalyzed posttranslational modifications and cross-linking to fibronectin. J Biochem 1994;115:675-682
56. Grundmann M, Woywodt A, Kirsch T, Hollwitz B, Oehler K, Erdbruegger U, et al. Circulating endothelial cells: a marker of vascular damage in patients with preeclampsia. Am J Obstet Gynecol 2008;198:317.e1-317.e5.
57. Nadar SK, Al Yemeni E, Blann AD, Lip GY. Thrombomodulin, von Willebrand factor and E-selectin as plasma markers of endothelial damage/dysfunction and activation in pregnancy induced hypertension. Thromb Res 2004;113:123-128