Caspase cleavage of Ets-1 p51 generates fragments with transcriptional dominant-negative function

Biochemical Journal

Volumn 426, Issue 2, 2010, Pages 229-241

  Choul Li, Souhaila ^a   Leroy, Catherine ^a   Leprivier, Gabriel ^a,b   Laitem, Clelia ^a,c   Tulasne, David ^a   Aumercier, Marc ^a  

^a UNIV LILLE   (France)

^b BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Apoptosis; Caspase; Ets 1 isoform; Exon VII encoded region; Transcriptional regulation

Indexed keywords

BINDING SITES; TRANSCRIPTION;

C-TERMINAL FRAGMENTS; CASPASES; EXON VII-ENCODED REGION; ISOFORMS; PATHOLOGICAL PROCESS; TRANSACTIVATION DOMAIN; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL REGULATION;

CELL DEATH;

CASPASE 3; PROTEIN P51; TRANSCRIPTION FACTOR ETS 1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DOWN REGULATION; EXON; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL LINE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; TRANSACTIVATION;

EID: 76549109444     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090877     Document Type: Article

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