Protective effect of squalene on certain lysosomal hydrolases and free amino acids in isoprenaline-induced myocardial infarction in rats

International Journal of Pharmacology

Volumn 6, Issue 2, 2010, Pages 97-103

  Farvin, K H S ^a,c   Surendraraj, A ^b,c   Anandan, R ^c  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b MADRAS VETERINARY COLLEGE   (India)

^c CENTRAL INSTITUTE OF FISHERIES TECHNOLOGY   (India)

Author keywords

Arginine; Aspartate; Glutamate; Hydroxyproline; Lysosomal hydrolases; Taurine

Indexed keywords

ACID PHOSPHATASE; AMINO ACID; ASPARTIC ACID; BETA GALACTOSIDASE; BETA GLUCOSIDASE; BETA GLUCURONIDASE; CATHEPSIN D; FREE RADICAL; HYDROXYPROLINE; ISOPRENALINE; LYSOSOME ENZYME; SQUALENE; TAURINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME BLOOD LEVEL; HEART INFARCTION; HEART MUSCLE FIBER MEMBRANE; HEART PROTECTION; LYSOSOME MEMBRANE; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 76549104422     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2010.97.103     Document Type: Article

References (41)

1. Agha, A.M. and Z.M. Gad, 1995. Lipid peroxidation and lysosomal integrity in different inflammatory models in rats. The effect of indomethacin and naptazone. Pharm. Res., 32: 279-285.
2. Aioi, A., T. Shimizu and K. Kuriyama, 1995. Effect of Squalene on superoxide anion generation induced by a skin irritant, lauroylsarcosine. Int. J. Pharm., 113: 159-164.
3. Arstall, M.A., D.B. Sawyer, R. Fukazawa and R.A. Kelly, 1999. Cytokine-mediated apoptosis in cardiac myocytes: The role of inducible nitric oxide synthase induction and peroxynitrite generation. Circ Res., 85: 829-840.
4. Backstrom, T., M. Goiny, U. Lockowandt, J. Liska and A. Franco-Cereceda, 2003. Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion. J. Applied Physiol., 94: 1122-1128.
5. Chapman, R.A., M.S. Suleiman and Y.E. Earm, 1993. Taurine and the heart. Cardiovasc Res., 27: 358-363.
6. Conchie, J., A.L. Gelman and G.A. Levry, 1967.. Inhibition of glycosidases by aldonolactones of corresponding configuration. The C-4 and C-6 specificity of beta-glucosidase and beta-galactosidase. Biochem. J., 103: 609-615.
7. Dessi, M.A., M. Deiana, B.W. Day, A. Rosa, S. Banni and F.P. Corongui, 2002. Oxidative stability of polyunsaturated fatty acids: Effect of squalene. Eur. J. Lipid Sci. Technol., 104: 506-512.
8. Farvin, K.H.S., R. Anandan, S.H.S. Kumar, K.S. Shiny, T.V. Sankar and T.K. Thankappan, 2004. Effect of squalene on tissue defence system in isoproterenol-induced myocardial infarction in rats. Pharmacol. Res., 50: 231-236.
9. Farvin, K.H.S., R. Anandan, T.V. Sankar and P.G.N. Viswanathan, 2005. Protective effect of squalene against isoproterenol-induced myocardial infarction in rats. J. Clin. Biochem. Nutr., 37: 55-60.
10. Farvin, K.H.S., R. Anandan, S.H.S. Kumar, K.S. Shiny, T.V. Sankar and P. G. V. Nair, 2006. Protective effect of squalene on changes in lipid profile in experimentally induced myocardial infarction in rats. J. Med. Food, 9: 531-536.
11. Farvin, K.H.S., S.H.S. Kumar, R. Anandan, S. Mathew, T.V. Sankar and P.G.V. Nair, 2007. Supplementation of squalene attenuates experimentally induced myocardial infarction in rats. Food Chem., 105: 1390-1395.
12. Ganesan, B. and R. Anandan, 2009. Protective effect of betaine on changes in the levels of lysosomal enzyme activities in heart tissue in isoprenaline-induced myocardial infarction in Wistar rats. Cell Stress Chaperones. 10.1007/s12192-009-0111-3
13. Gupta, R. and V.P. Gupta, 1998. Lessions for prevention of coronary heart disease epidemiological study in Western India. Curr. Sci., 74: 1074-1077.
14. Gustafsson, A.B. and L.L. Brunton, 2000. Beta-adrenergic stimulation of rat cardiac fibroblasts enhances induction of nitric-oxide synthase by interleukin-1beta via message stabilization. Mol. Pharmacol., 58: 1470-1478.
15. Haines, T.H., 2001. Do sterols reduce proton and sodium leaks through lipid bilayers?. Prog. Lipid Res., 40: 299-324.
16. Hayashi, K. and T. Takagi, 1981. Distribution of squalene and diacyl glyceryl ethers in the different tissue of deep sea shark, Dalatias licha. Bull. Jpn. Soc. Sci. Fish., 47: 281-288.
17. Ishada, Y., T. Fugita and K. Asai, 1981. New detection and separation method for aminoacid by high performance liquid chromatography. J. Chromato., 204: 143-148.
18. Ivashkevich, S.P., L.I. Apukhovskaia and V.P. Vendt, 1981. Effects of sterols having different chemical structure and squalene on osmotic resistance of erythrocytes. Biokhimiia, 46: 1420-1425.
19. Kalra, J., K. Lautner, L. Massey and K. Prasad, 1988. Oxygen free radicals induced release of lysosomal enzymes in vitro. Mol. Cell Biochem., 84: 233-238.
20. Kawai, Y. and K. Anno, 1971. Mucopolysaccharides degrading enzymes from the liver of the squid ommastrephes solani paciicus L. hyaluronidase. Biochim. Biophys. Acta., 242: 428-436.
21. Keith, M.E., A. Ball, K.N. Jeejeebhoy, R. Kurian and J. Butany et al., 2001. Conditioned nutritional deficiencies in the cardiomyopathic hamster heart. Can. J. Cardiol., 17: 449-458.
22. King, J., 1965. The Hydrolases-Acid and Alkaline Phosphatases. In: Practical Clinical Enzymology, Van, D. (Ed.). Nostrand Company Limited, London, pp: 191-208.
23. Ko, T.F., T.M. Weng and R.Y. Chiou, 2002. Squalene content and antioxidant activity of Terminalia catappa leaves and seeds. J. Agric. Food Chem., 50: 5343-5348.
24. Kohno, Y., Y. Egawa and S. Itoh, 1995. Kinetic study of quenching reaction of singlet oxygen and scavenging reaction of free radical by squalene in n-butanol. Biochim. Biophys. Acta, 1257: 52-56.
25. Krishnaswami, S., 1998. Observations on serial changes in coronary artety disease in Indians. Curr. Sci., 74: 1064-1068.
26. Nirmala, C. and R. Puvanakrishnan, 1996. Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats. Biochem. Pharmacol., 51: 47-51.
27. Okuda, M. and A.M. Lefer, 1979. Lysosomal hypothesis in evolution of myocardial infarction. Subcellular fractionation and electron microscopic cytochemical study. Jpn. Heart. J., 20: 643-656.
28. Passi, S., O. De-Pita, P. Puddu and G.P. Littarru, 2002. Lipophilic antioxidants in human sebum and aging. Free Radic. Res., 36: 471-477.
29. Qureshi, A.A., J.W. Lehman and D.M. Peterson, 1996. Amaranth and its oil inhibit cholesterol biosynthesis in six week old female chickens. J. Nutr., 126: 1972-1978.
30. Ravichandran, L.V., R. Puvanakrishnan and T.K. Joseph, 1990. Alterations in heart lysosomal stability in isoproterenol induced myocardial infarction in rats. Biochem. Int., 22: 387-396.
31. Reddy, K.S., 2002. Cardiovascular diseases in the developing countries: Dimensions, determinants, dynamics and directions for public health action. Public Health Nutr., 5: 231-237.
32. Richter, E. and S.G. Schafer, 1982. Effect of squalene on hexachlorobenzene (HCB) concentrations in tissue of mice. J. Environ. Sci. Health, 17: 195-203.
33. Sapolsky, A.L., R.D. Altman and D.S. Howell, 1973. Cathepsin-D activity in normal and ostearthritic human cartilage. Fed. Proc., 32: 1489-1493.
34. Song, D., M.H. O'Regan and J.W. Phillis, 1996. Release of excitotoxic amino acids, glutamate and aspartate, from the isolated ischemic/anoxic rat heart. Neurosci. Lett., 220: 1-4.
35. Steenbergen, C., M.L. Hill and R.B. Jennings, 1985. Volume regulation and plasma membrane injury in aerobic, anaerobic and ischemic myocardium in vitro. Effects of osmotic cell swelling on plasma membrane integrity. Circ. Res., 57: 864-875.
36. Tilvis, R.S. and T.A. Miettinen, 1983. Dietary squalene increases tissue sterols and fecal bile acids in the rat. Lipids, 18: 32-36.
37. Upasani, C.D. and R. Balaraman, 2001. Effect of vitamin E., Vitamin C and spirulina on the levels of membrane bound enzymes and lipids in some organs of rats exposed to lead. Ind. J. Pharmacol., 33: 185-191.
38. Warskulat, U., U. Flogel, C. Jacoby, H.G. Hartwig and M. Thewissen et al., 2004. Taurine transporter knockout depletes muscle taurine levels and results in severe skeletal muscle impairment but leaves cardiac function uncompromised. FASEB J., 18: 577-579.
39. Wattiaux, R., 1977. Mammalian Cell Membranes. 2nd Edn., Butterworth, London, pp: 165.
40. Wildenthal, K., 1978. Lysosomal alterations in ischemic myocardium: Result or cause of myocellular damage?. J. Mol. Cell. Cardiol., 10: 595-603.
41. Xu, R.B., W.W. Liu and M.Y. Wang, 2005. Progress of preparation and application in squalene. Shand. J. Med., 45: 69-70.