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1
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Factors affecting women's selection of a combined hormonal contraceptive method: The TEAM-06 Spanish cross-sectional study
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This article compares acceptability rates for the contraceptive IVR, pill, and skin patch
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Lete I, Doval JL, Perez-Campos E, et al. Factors affecting women's selection of a combined hormonal contraceptive method: The TEAM-06 Spanish cross-sectional study. Contraception 2007; 76:77-83. This article compares acceptability rates for the contraceptive IVR, pill, and skin patch.
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Lete, I.1
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This article compares acceptability rates for pill users randomized to the IVR or skin patch
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Creinin MD, Meyn LA, Borgatta L, et al. Multicenter comparison of the contraceptive ring and patch: a randomized controlled trial. Obstet Gynecol 2008; 111 (2 Pt 1):267-277. This article compares acceptability rates for pill users randomized to the IVR or skin patch.
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This article describes acceptability of the IVR, especially as related to insertion and removal
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Merki-Feld GS, Hund M. Clinical experience with NuvaRing® in daily practice in Switzerland: Cycle control and acceptability among women of all reproductive ages. Eur J Contracept Reprod Heath Care 2007; 12:240-247. This article describes acceptability of the IVR, especially as related to insertion and removal.
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Ahrendt HJ, Nisand I, Bastianelli C, et al. Efficacy, acceptability and tolerability of the combined contraceptive ring, NuvaRing, compared with an oral contraceptive containing 30 microg of ethinyl estradiol and 3mg of drospirenone. Contraception 2006; 74:451-457.
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Schafer JE, Osborne LM, Davis AR, Westhoff C. Acceptability and satisfaction using Quick Start with the contraceptive vaginal ring versus an oral contraceptive. Contraception 2006; 73:488-492.
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10
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This article describes the use and acceptability of a new microbicide product with an applicator that serves as a mechanical barrier
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Ballagh SA, Brache V, Mauck C, et al. A phase I study of the functional performance, safety and acceptability of the BufferGel Duet. Contraception 2008; 77:130-137. This article describes the use and acceptability of a new microbicide product with an applicator that serves as a mechanical barrier.
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Ballagh, S.A.1
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Balzarini J, Van Damme L. Microbicide drug candidates to prevent HIV infection. Lancet 2007; 369:787-797. This review article describes different categories of microbicide drugs, their mechanisms of action and status of development. Progress in phase III trials is reported.
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12
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Balzarini J, Van Damme L. Intravaginal and intrarectal microbicides to prevent HIV infection. CMAJ 2005; 172:461-464.
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Olmsted SS, Khanna KV, Ng EM, et al. Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model. BMC Infect Dis 2005; 5:79.
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This paper reports on the in-vitro binding of HIV-1 to epithelial cells in the presence of microbicide gels currently in preclinical and clinical trials
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Roth S, Monsour M, Dowland A, et al. Effect of Topical microbicides on infectious human immunodeficiency virus type 1 binding to epithelial cells. Antimicrob Agents Chemother 2007; 51:1972-1978. This paper reports on the in-vitro binding of HIV-1 to epithelial cells in the presence of microbicide gels currently in preclinical and clinical trials.
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Trifonova RT, Pasicznyk JM, Fichorova RN. Biocompatibility of solid-dosage formsof antihuman immunodeficiency virus type 1 microbicideswith the human cervicovaginal mucosa modeled ex vivo. Antimicrob Agents Chemother 2006; 50:4005-4010.
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Alliance for Microbicide Development. Microbicide candidates in clinical development. Microbicide Quarterly 2007; 5: 4. http://www.microbicide. org/microbicideinfo/reference/TMQ.Apr-Jun2007.FINAL.pdf. [Accessed 17 March 2008].
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This study established the safety and acceptability of the Invisible Condom. It is now in phase I/II clinical trials
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Trottier S, Omar RE, Désormeaux A, et al. Safety, tolerance and acceptability of the Invisible Condom and its vaginal applicator in healthy women and their male sexual partners. Contraception 2007; 76:117-125. This study established the safety and acceptability of the Invisible Condom. It is now in phase I/II clinical trials.
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This paper describes the in-vitro anti-HIV effect of PC-815, a combination gel product containing Carraguard and the NNRTI MIV-150
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Fernandez-Romero JA, Thorn M, Turville SG, et al. Carrageenan/MIV-150 (PC-815): a combination microbicide. Sex Transm Dis 2007; 34:9-14. This paper describes the in-vitro anti-HIV effect of PC-815, a combination gel product containing Carraguard and the NNRTI MIV-150.
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Indevus Pharmaceuticals Provides Update on PRO 2000 Program. http:// phx.corporate-ir.net/phoenix.zhtml?c=92810&p=irol-newsArticle&ID= 1108774 &highlight=. [Accessed on 18 March 2008].
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This paper established that PRO2000, which is now in phase III, is acceptable to Indian women
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Joglekar N, Joshi S, Kakde M, et al. Acceptability of PRO2000 vaginal gel among HIV un-infected women in Pune, India. AIDS Care 2007; 19:817-821. This paper established that PRO2000, which is now in phase III, is acceptable to Indian women.
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Feldblum PJ, Adeiga A, Bakare R, et al. SAVVY vaginal gel (C31G) for prevention of HIV infection: a randomized controlled trial in Nigeria. PLoS ONE 2008; 3:e1474. This phase III study showed that SAVVY did not reduce HIV infection.
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Peterson L, Nanda K, Opoku BK, et al. SAVVY® (C31G) gel for prevention of HIV infection in women: a phase 3, double-blind, randomized, placebo-controlled trial in Ghana. PLoS ONE 2007; 2:e1312. This phase III study was not able to show that SAVVY use was associated with reduction of HIV incidence. Although not associated with a higher incidence of adverse events overall, it was associated with a higher incidence of reproductive adverse events.
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