Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4-O-carbamate derivatives

Journal of Antibiotics

Volumn 63, Issue 1, 2010, Pages 3-8

  Ma, Chenchen ^a   Liu, Zhaopeng ^a   Song, Hualong ^a   Jiang, Rentao ^a   He, Fawen ^a   Ma, Shutao ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

4 O carbamate derivatives; Antibacterial activity; Macrolides; Resistance; Synthesis

Indexed keywords

4'' O [[(2 CHLOROPHENETHYL)AMINO] 4 OXOBUTYL]CARBAMOYLAZITHROMYCIN 11,12 CYCLIC CARBONATE; 4'' O [[(3 CHLOROBENZYL)AMINO] 4 OXOBUTYL]CARBAMOYLAZITHROMYCIN 11,12 CYCLIC CARBONATE; 4'' O [[(4 HYDROXYPHENETHYL)AMINO] 4 OXOBUTYL]CARBAMOYLAZITHROMYCIN 11,12 CYCLIC CARBONATE; 4'' O [[(4 METHOXYBENZYL)AMINO] 4 OXOBUTYL]CARBAMOYLAZITHROMYCIN 11,12 CYCLIC CARBONATE; 4'' O [[(PHENETHYL)AMINO] 4 OXOBUTYL]CARBAMOYLAZITHROMYCIN 11,12 CYCLIC CARBONATE; AZITHROMYCIN; CARBAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GENE; DRUG DESIGN; DRUG SYNTHESIS; ERM GENE; IN VITRO STUDY; MEF GENE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; BACTERIAL PROTEINS; CARBAMATES; CARBONATES; DRUG RESISTANCE, BACTERIAL; ERYTHROMYCIN; MEMBRANE PROTEINS; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; STRUCTURE-ACTIVITY RELATIONSHIP;

STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

EID: 76449114848     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2009.108     Document Type: Article

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