Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors

Thrombosis Research

Volumn 125, Issue 2, 2010, Pages 159-165

  Chang, Hung ^a,b   Yanachkov, Ivan B ^c   Michelson, Alan D ^a,d   Li, YouFu ^a   Barnard, M R ^a,d   Wright, George E ^c   Frelinger III, Andrew L ^a,d  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c GLSYNTHESIS INC   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

ADP; diadenosine tetraphosphate; platelet aggregation; platelets; purinergic receptors

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIUM ION; DIADENOSINE TETRAPHOSPHATE; PURINERGIC P2X1 RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y12 RECEPTOR; VASODILATOR STIMULATED PHOSPHOPROTEIN;

AGONIST; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYTOSOL; EXTRACELLULAR CALCIUM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INHIBITION KINETICS; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTE SHAPE;

BLOOD PLATELETS; CYTOPLASMIC GRANULES; DINUCLEOSIDE PHOSPHATES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; RECEPTORS, PURINERGIC P2;

EID: 76449090320     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.11.006     Document Type: Article

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