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Volumn 54, Issue 3, 2004, Pages 665-675

Intestinal barrier dysfunction by enteropathogenic Escherichia coli is mediated by two effector molecules and a bacterial surface protein

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL SURFACE PROTEIN; INTIMIN; MEMBRANE PROTEIN; MITOCHONDRIA ASSOCIATED PROTEIN; OUTER MEMBRANE PROTEIN; PROTEIN ESPF; PROTEIN TIR; RECEPTOR; UNCLASSIFIED DRUG;

EID: 7644225138     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2004.04308.x     Document Type: Article
Times cited : (154)

References (35)
  • 1
    • 0038054523 scopus 로고    scopus 로고
    • Bacterial invasion by a paracellular route: Divide and conquer
    • Balkovetz, D.F., and Katz, J. (2003) Bacterial invasion by a paracellular route: divide and conquer. Microbes Infect 5: 613-619.
    • (2003) Microbes Infect , vol.5 , pp. 613-619
    • Balkovetz, D.F.1    Katz, J.2
  • 2
    • 0027302362 scopus 로고
    • Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers
    • Canil, C., Rosenshine, I., Ruschkowski, S., Donnenberg, M.S., Kaper, J.B., and Finlay, B.B. (1993) Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers. Infect Immun 61: 2755-2762.
    • (1993) Infect Immun , vol.61 , pp. 2755-2762
    • Canil, C.1    Rosenshine, I.2    Ruschkowski, S.3    Donnenberg, M.S.4    Kaper, J.B.5    Finlay, B.B.6
  • 4
    • 0031775047 scopus 로고    scopus 로고
    • Enteropathogenic Escherichia coli virulence genes encoding secreted signalling proteins are essential for modulation of Caco-2 cell electrolyte transport
    • Collington, G.K., Booth, I.W., Donnenberg, M.S., Kaper, J.B., and Knutton, S. (1998) Enteropathogenic Escherichia coli virulence genes encoding secreted signalling proteins are essential for modulation of Caco-2 cell electrolyte transport. Infect Immun 66: 6049-6053.
    • (1998) Infect Immun , vol.66 , pp. 6049-6053
    • Collington, G.K.1    Booth, I.W.2    Donnenberg, M.S.3    Kaper, J.B.4    Knutton, S.5
  • 5
    • 0026411101 scopus 로고
    • Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive selection suicide vector
    • Donnenberg, M.S., and Kaper, J.B. (1991) Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive selection suicide vector. Infect Immun 59: 4310-4317.
    • (1991) Infect Immun , vol.59 , pp. 4310-4317
    • Donnenberg, M.S.1    Kaper, J.B.2
  • 6
    • 0025285812 scopus 로고
    • Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells
    • Donnenberg, M.S., Calderwood, S.B., Donohuerolfe, A., Keusch, G.T., and Kaper, J.B. (1990) Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells. Infect Immun 58: 1561-1571.
    • (1990) Infect Immun , vol.58 , pp. 1561-1571
    • Donnenberg, M.S.1    Calderwood, S.B.2    Donohuerolfe, A.3    Keusch, G.T.4    Kaper, J.B.5
  • 7
    • 0035024818 scopus 로고    scopus 로고
    • EspG, a novel type III system-secreted protein from enteropathogenic Escherichia coli with similarities to VirA of Shigella flexneri
    • Elliott, S.J., Krejany, E.O., Mellies, J.L., Robins-Browne, R.M., Sasakawa, C., and Kaper, J.B. (2001) EspG, a novel type III system-secreted protein from enteropathogenic Escherichia coli with similarities to VirA of Shigella flexneri. Infect Immun 69: 4027-4033.
    • (2001) Infect Immun , vol.69 , pp. 4027-4033
    • Elliott, S.J.1    Krejany, E.O.2    Mellies, J.L.3    Robins-Browne, R.M.4    Sasakawa, C.5    Kaper, J.B.6
  • 8
    • 0029808317 scopus 로고    scopus 로고
    • The cell binding domain of intimin from enteropathogenic Escherichia coli binds to beta(1) integrins
    • Frankel, G., Lider, O., Hershkoviz, R., Mould, A.P., Kachalsky, S.G., Candy, D.C.A., et al. (1996) The cell binding domain of intimin from enteropathogenic Escherichia coli binds to beta(1) integrins. J Biol Chem 271: 20359-20364.
    • (1996) J Biol Chem , vol.271 , pp. 20359-20364
    • Frankel, G.1    Lider, O.2    Hershkoviz, R.3    Mould, A.P.4    Kachalsky, S.G.5    Candy, D.C.A.6
  • 9
    • 0036088604 scopus 로고    scopus 로고
    • Rac1, but not RhoA, signaling protects epithelial adherens junction assembly during ATP depletion
    • Gopalakrishnan, S., Dunn, K.W., and Marrs, J.A. (2002) Rac1, but not RhoA, signaling protects epithelial adherens junction assembly during ATP depletion. Am J Physiol Cell Physiol 283: C261-C272.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Gopalakrishnan, S.1    Dunn, K.W.2    Marrs, J.A.3
  • 11
    • 0142248438 scopus 로고    scopus 로고
    • Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells
    • Jepson, M.A., Pellegrin, S., Peto, L., Banbury, D.N., Leard, A.D., Mellor, H., and Kenny, B. (2003) Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells. Cell Microbiol 5: 773-783.
    • (2003) Cell Microbiol , vol.5 , pp. 773-783
    • Jepson, M.A.1    Pellegrin, S.2    Peto, L.3    Banbury, D.N.4    Leard, A.D.5    Mellor, H.6    Kenny, B.7
  • 12
    • 0036064379 scopus 로고    scopus 로고
    • Enteropathogenic Escherichia coli (EPEC) - A crafty subversive little bug
    • Kenny, B. (2002) Enteropathogenic Escherichia coli (EPEC) - a crafty subversive little bug. Microbiology 148: 1967-1978.
    • (2002) Microbiology , vol.148 , pp. 1967-1978
    • Kenny, B.1
  • 13
    • 0034518855 scopus 로고    scopus 로고
    • Targeting of an enteropathogenic Escherichia coli (EPEC) effector protein to host mitochondria
    • Kenny, B., and Jepson, M. (2000) Targeting of an enteropathogenic Escherichia coli (EPEC) effector protein to host mitochondria. Cell Microbiol 2: 579-590.
    • (2000) Cell Microbiol , vol.2 , pp. 579-590
    • Kenny, B.1    Jepson, M.2
  • 14
    • 0030701868 scopus 로고    scopus 로고
    • Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells
    • Kenny, B., DeVinney, R., Stein, M., Reinscheid, D.J., Frey, E.A., and Finlay, B.B. (1997) Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 91: 511-520.
    • (1997) Cell , vol.91 , pp. 511-520
    • Kenny, B.1    DeVinney, R.2    Stein, M.3    Reinscheid, D.J.4    Frey, E.A.5    Finlay, B.B.6
  • 15
    • 0036096793 scopus 로고    scopus 로고
    • Co-ordinate regulation of distinct host cell signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules
    • Kenny, B., Ellis, S., Leard, A.D., Warawa, J., Mellor, H., and Jepson, M.A. (2002) Co-ordinate regulation of distinct host cell signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules. Mol Microbiol 44: 1095-1107.
    • (2002) Mol Microbiol , vol.44 , pp. 1095-1107
    • Kenny, B.1    Ellis, S.2    Leard, A.D.3    Warawa, J.4    Mellor, H.5    Jepson, M.A.6
  • 16
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmlli, U. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmlli, U.1
  • 17
    • 0034733884 scopus 로고    scopus 로고
    • The molecular structure of the tight junction
    • Lapierre, L.A. (2000) The molecular structure of the tight junction. Adv Drug Deliv Rev 41: 255-264.
    • (2000) Adv Drug Deliv Rev , vol.41 , pp. 255-264
    • Lapierre, L.A.1
  • 18
    • 0021825282 scopus 로고
    • The diarrheal response of humans to some classical serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor
    • Levine, M.M., Nataro, J.P., Karch, H., Baldini, M.M., Kaper, J.B., and Black, K.L. (1985) The diarrheal response of humans to some classical serotypes of enteropathogenic Escherichia coli is dependent on a plasmid encoding an enteroadhesiveness factor. J Infect Dis 152: 550-559.
    • (1985) J Infect Dis , vol.152 , pp. 550-559
    • Levine, M.M.1    Nataro, J.P.2    Karch, H.3    Baldini, M.M.4    Kaper, J.B.5    Black, K.L.6
  • 19
    • 0031711022 scopus 로고    scopus 로고
    • A novel proline-rich protein, EspF, is secreted from enteropathogenic Escherichia coli via the type III export pathway
    • McNamara, B.P., and Donnenberg, M.S. (1998) A novel proline-rich protein, EspF, is secreted from enteropathogenic Escherichia coli via the type III export pathway. FEMS Microbiol Lett 166: 71-78.
    • (1998) FEMS Microbiol Lett , vol.166 , pp. 71-78
    • McNamara, B.P.1    Donnenberg, M.S.2
  • 20
    • 0035095037 scopus 로고    scopus 로고
    • Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function
    • McNamara, B.P., Koutsouris, A., O'Connell, C.B., Nougayrede, J.P., Donnenberg, M.S., and Hecht, G. (2001) Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function. J Clin Invest 107: 621-629.
    • (2001) J Clin Invest , vol.107 , pp. 621-629
    • McNamara, B.P.1    Koutsouris, A.2    O'Connell, C.B.3    Nougayrede, J.P.4    Donnenberg, M.S.5    Hecht, G.6
  • 21
    • 0029051550 scopus 로고
    • FK506 increases permeability in rat intestine by inhibiting mitochondrial function
    • Madsen, K.L., Yanchar, N.L., Sigalet, D.L., Reigel, T., and Fedorak, R.N. (1995) FK506 increases permeability in rat intestine by inhibiting mitochondrial function. Gastroenterology 109: 107-114.
    • (1995) Gastroenterology , vol.109 , pp. 107-114
    • Madsen, K.L.1    Yanchar, N.L.2    Sigalet, D.L.3    Reigel, T.4    Fedorak, R.N.5
  • 22
    • 0027339375 scopus 로고
    • Uncoupling of the molecular fence and paracellular gate functions in epithelial tight junctions
    • Mandel, L.J., Bacallo, R., and Zampighi, G. (1993) Uncoupling of the molecular fence and paracellular gate functions in epithelial tight junctions. Nature 361: 552-555.
    • (1993) Nature , vol.361 , pp. 552-555
    • Mandel, L.J.1    Bacallo, R.2    Zampighi, G.3
  • 23
    • 0344851638 scopus 로고    scopus 로고
    • Disruption of cell polarity by enteropathogenic Escherichia coli enables basolateral membrane proteins to migrate apically and to potentiate physiological consequences
    • Muza-Moons, M.M., Koutsouris, A., and Hecht, G. (2003) Disruption of cell polarity by enteropathogenic Escherichia coli enables basolateral membrane proteins to migrate apically and to potentiate physiological consequences. Infect Immun 71: 7069-7078.
    • (2003) Infect Immun , vol.71 , pp. 7069-7078
    • Muza-Moons, M.M.1    Koutsouris, A.2    Hecht, G.3
  • 24
    • 0031984684 scopus 로고    scopus 로고
    • Diarrheagenic Escherichia coli
    • Nataro, J.P., and Kaper, J.B. (1998) Diarrheagenic Escherichia coli. Clin Microbiol Rev 11: 142-201.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 142-201
    • Nataro, J.P.1    Kaper, J.B.2
  • 25
    • 0034040795 scopus 로고    scopus 로고
    • Intimin from enteropathogenic Escherichia coli mediates remodelling of the eukaryotic cell surface
    • Phillips, A.D., Giron, J., Hicks, S., Dougan, G., and Frankel, G. (2000) Intimin from enteropathogenic Escherichia coli mediates remodelling of the eukaryotic cell surface. Microbiology 146: 1333-1344.
    • (2000) Microbiology , vol.146 , pp. 1333-1344
    • Phillips, A.D.1    Giron, J.2    Hicks, S.3    Dougan, G.4    Frankel, G.5
  • 26
    • 0030007493 scopus 로고    scopus 로고
    • Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions
    • Philpott, D.J., McKay, D.M., Sherman, P.M., and Perdue, M.H. (1996) Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions. Am J Physiol 33: G634-G645.
    • (1996) Am J Physiol , vol.33
    • Philpott, D.J.1    McKay, D.M.2    Sherman, P.M.3    Perdue, M.H.4
  • 27
    • 0034799581 scopus 로고    scopus 로고
    • EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption
    • Savkovic, S.D., Ramaswamy, A., Koutsouris, A., and Hecht, G. (2001) EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruption. Am J Physiol 281: G890-G898.
    • (2001) Am J Physiol , vol.281
    • Savkovic, S.D.1    Ramaswamy, A.2    Koutsouris, A.3    Hecht, G.4
  • 28
    • 0033853899 scopus 로고    scopus 로고
    • Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions
    • Simonovic, I., Rosenberg, J., Koutsouris, A., and Hecht, G. (2000) Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions. Cell Microbiol 2: 305-315.
    • (2000) Cell Microbiol , vol.2 , pp. 305-315
    • Simonovic, I.1    Rosenberg, J.2    Koutsouris, A.3    Hecht, G.4
  • 29
    • 0037169481 scopus 로고    scopus 로고
    • Cell surface-localized nucleolin is a eukaryotic receptor for the adhesin intimin-gamma of enterohemorrhagic Escherichia coli O157:H7
    • Sinclair, J.F., and O'Brien, A.D. (2002) Cell surface-localized nucleolin is a eukaryotic receptor for the adhesin intimin-gamma of enterohemorrhagic Escherichia coli O157:H7. J Biol Chem 277: 2876-2885.
    • (2002) J Biol Chem , vol.277 , pp. 2876-2885
    • Sinclair, J.F.1    O'Brien, A.D.2
  • 30
    • 0028961732 scopus 로고
    • Enteropathogenic Escherichia coli adherence to intestinal epithelial monolayers diminishes barrier function
    • Spitz, J., Yuhan, R., Koutsouris, A., Blatt, C., Alverdy, J., and Hecht, G. (1995) Enteropathogenic Escherichia coli adherence to intestinal epithelial monolayers diminishes barrier function. Am J Physyol 31: G374-G379.
    • (1995) Am J Physyol , vol.31
    • Spitz, J.1    Yuhan, R.2    Koutsouris, A.3    Blatt, C.4    Alverdy, J.5    Hecht, G.6
  • 31
    • 0037238121 scopus 로고    scopus 로고
    • EspH, a new cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli
    • Tu, X.L., Nisan, I., Yona, C., Hanski, E., and Rosenshine, I. (2003) EspH, a new cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli. Mol Microbiol 47: 595-606.
    • (2003) Mol Microbiol , vol.47 , pp. 595-606
    • Tu, X.L.1    Nisan, I.2    Yona, C.3    Hanski, E.4    Rosenshine, I.5
  • 32
    • 0032868135 scopus 로고    scopus 로고
    • Type III secretion-dependent hemolytic activity of enteropathogenic Escherichia coli
    • Warawa, J., Finlay, B.B., and Kenny, B. (1999) Type III secretion-dependent hemolytic activity of enteropathogenic Escherichia coli. Infect Immun 67: 5538-5540.
    • (1999) Infect Immun , vol.67 , pp. 5538-5540
    • Warawa, J.1    Finlay, B.B.2    Kenny, B.3
  • 33
    • 7644228592 scopus 로고
    • Enteropathogenic E. coli induced phosphorylation of myosin light chain increases intestinal epithelial paracellular permeability
    • Yuhan, R., Koutsouris, A., and Hecht, G. (1995) Enteropathogenic E. coli induced phosphorylation of myosin light chain increases intestinal epithelial paracellular permeability. Gastroenterology 108: A948-A948.
    • (1995) Gastroenterology , vol.108
    • Yuhan, R.1    Koutsouris, A.2    Hecht, G.3
  • 34
    • 0035578711 scopus 로고    scopus 로고
    • Collective efforts to modulate the host actin cytoskeleton by Salmonella type III-secreted effector proteins
    • Zhou, D.G. (2001) Collective efforts to modulate the host actin cytoskeleton by Salmonella type III-secreted effector proteins. Trends Microbiol 9: 567-569.
    • (2001) Trends Microbiol , vol.9 , pp. 567-569
    • Zhou, D.G.1
  • 35
    • 0036305854 scopus 로고    scopus 로고
    • A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
    • Zolotarevsky, Y., Hecht, G., Koutsouris, A., Gonzalez, D.E., Quan, C., Tom, J., et al. (2002) A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123: 163-172.
    • (2002) Gastroenterology , vol.123 , pp. 163-172
    • Zolotarevsky, Y.1    Hecht, G.2    Koutsouris, A.3    Gonzalez, D.E.4    Quan, C.5    Tom, J.6


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