Doxycyline inhibits mononuclear cell-mediated connective tissue breakdown

FEMS Immunology and Medical Microbiology

Volumn 58, Issue 2, 2010, Pages 218-225

  Gu, Ying ^a   Lee, Hsi Ming ^a   Sorsa, Timo ^b   Simon, Sanford R ^c   Golub, Lorne M ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Cytokine; Doxycycline; Extracellular matrix; Lipopolysaccharide; Matrix metalloproteinase; Monocyte

Indexed keywords

COLLAGENASE; CYTOKINE; DOXYCYCLINE; GELATINASE B; GELATINASE; IMMUNOLOGIC FACTOR; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CARDIOVASCULAR DISEASE; CHRONIC INFLAMMATION; CONNECTIVE TISSUE; DEGRADATION; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME INHIBITION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MACROPHAGE; MONONUCLEAR CELL; PERIODONTITIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PLEIOTROPY; PRIORITY JOURNAL; RISK REDUCTION; CELL CULTURE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; SECRETION;

CELLS, CULTURED; COLLAGENASES; DOXYCYCLINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; GELATINASES; HUMANS; IMMUNOBLOTTING; IMMUNOLOGIC FACTORS; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; MATRIX METALLOPROTEINASE 9; TUMOR NECROSIS FACTOR-ALPHA;

EID: 76349120589     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2009.00625.x     Document Type: Article

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