Single-molecule DNA biosensors for protein and ligand detection

Angewandte Chemie - International Edition

Volumn 49, Issue 7, 2010, Pages 1316-1320

  Lymperopoulos, Konstantinos ^a,b   Crawford, Robert ^a   Torella, Joseph P ^a   Heilemann, Mike ^a,c   Hwang, Ling Chin ^a   Holden, Seamus J ^a   Kapanidis, Achillefs N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c BIELEFELD UNIVERSITY   (Germany)

Author keywords

Biosensors; Laser spectroscopy; Protein dna interactions; Single molecule studies; Transcription factors

Indexed keywords

BIOLOGICAL SAMPLES; CHEMICAL EQUATIONS; DNA BIOSENSORS; FLUORESCENCE ASSAY; PROTEIN-DNA INTERACTIONS; SINGLE-MOLECULE; SINGLE-MOLECULE STUDIES; SMALL MOLECULES; SOLID SUPPORTS;

BINDING ENERGY; BINDING SITES; BIOSENSORS; COMPLEXATION; DNA; GENES; LASER SPECTROSCOPY; MOLECULES; STOICHIOMETRY; SUGAR (SUCROSE); TRANSCRIPTION FACTORS;

TRANSCRIPTION;

DNA; ISOPROPYL THIOGALACTOSIDE; LIGAND; TRANSCRIPTION FACTOR;

ARTICLE; CHEMISTRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC PROCEDURES; PROTEIN BINDING;

BIOSENSING TECHNIQUES; DNA; FLUORESCENCE RESONANCE ENERGY TRANSFER; ISOPROPYL THIOGALACTOSIDE; LIGANDS; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 76349117468     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200904597     Document Type: Article

References (24)

1. C. Branden, J. Tooze, Introduction to Protein Structure, Garland Publishing, New York, 1999.
2. B. Vogelstein, D. Lane, A. J. Levine, Nature 2000, 408, 307.
3. S. Fredriksson, M. Gullberg, J. Jarvius, C. Olsson, K. Pietras, S. M. Gustafsdottir, A. Ostman, U. Landegren, Nat. Biotechnol. 2002, 20, 473.
4. E. Heyduk, Y. Fei, T. Heyduk, Comb. Chem. High Throughput Screening 2003, 6, 347.
5. E. Heyduk, E. Knoll, T. Heyduk, Anal. Biochem. 2003, 316, 1.
6. T. Heyduk, E. Heyduk, Nat. Biotechnol. 2002, 20, 171.
7. A. N. Kapanidis, N. K. Lee, T. A. Laurence, S. Doose, E. Margeat, S. Weiss, Proc. Natl. Acad. Sci. USA 2004, 101, 8936.
8. Y. Santoso, L. C. Hwang, L. Le Reste, A. N. Kapanidis, Biochem. Soc. Trans. 2008, 36, 738.
9. N. K. Lee, A. N. Kapanidis, Y. Wang, X. Michalet, J. Mukhopadhyay, R. H. Ebright, S. Weiss, Biophys. J. 2005, 88, 2939.
10. R. H. Ebright, Y. W. Ebright, A. Gunasekera, Nucleic Acids Res. 1989, 17, 10295.
11. M. Fried, D. M. Crothers, Nucleic Acids Res. 1981, 9, 6505.
12. C. M. Falcon, K. S. Matthews, Biochemistry 2000, 39, 11074.
13. K. J. Breslauer, R. Frank, H. Blocker, L. A. Marky, Proc. Natl. Acad. Sci. USA 1986, 83, 3746.
14. M. J. Lane, T. Paner, I. Kashin, B. D. Faldasz, B. Li, F. J. Gallo, A. S. Benight, Nucleic Acids Res. 1997, 25, 611.
15. M. D. Barkley, A. D. Riggs, A. Jobe, S. Burgeois, Biochemistry 1975, 14, 1700.
16. M. Lewis, C. R. Biol. 2005, 328, 521.
17. A. D. Riggs, R. F. Newby, S. Bourgeois, J. Mol. Biol. 1970, 51, 303.
18. E. Southern, K. Mir, M. Shchepinov, Nat. Genet. 1999, 21, 5.
19. S. B. Zimmerman, S. O. Trach, J. Mol. Biol. 1991, 222, 599.
20. N. M. Nichols, K. S. Matthews, Biochemistry 2001, 40, 3847.
21. M. de Lumley, D. J. Hart, M. A. Cooper, S. Symeonides, J. M. Blackburn, J. Mol. Biol. 2004, 339, 1059.
22. M. S. Ozers, J. J. Hill, K. Ervin, J. R. Wood, A. M. Nardulli, C. A. Royer, J. Gorski, J. Biol. Chem. 1997, 272, 30405.
23. L. Ma, J. Wagner, J.J. Rice, W. Hu, A. J. Levine, G.A. Stolovitzky, Proc. Natl. Acad. Sci. USA 2005, 102, 14266.
24. J. Elf, G. W. Li, X. S. Xie, Science 2007, 316, 1191.