Linaclotide - A secretagogue and antihyperalgesic agent - What next?

Neurogastroenterology and Motility

Volumn 22, Issue 3, 2010, Pages 227-231

  Bharucha, A E ^a   Linden, D R ^a  

^a Clinical Enteric Neuroscience Translational and Epidemiological Research Mayo Clinic   (United States)

Author keywords

Colorectal distension; Functional bowel disorders; Irritable bowel syndrome; ST enterotoxin receptor; Visceral hypersensitivity

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CYCLIC AMP; CYCLIC GMP; ENDOCANNABINOID; GASTROINTESTINAL AGENT; GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; GUANYLATE CYCLASE C; GUANYLIN; LINACLOTIDE; LUBIPROSTONE; NEUROKININ 1 RECEPTOR; PRUCALOPRIDE; TEGASEROD; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG; UROGUANYLIN; VANILLOID RECEPTOR 1; VASOPRESSIN RECEPTOR; WATER;

ABDOMINAL DISCOMFORT; BLOATING; CELL PROLIFERATION; CLINICAL TRIAL; COLITIS; COLON DILATATION; CONSTIPATION; DIGESTIVE SYSTEM FUNCTION DISORDER; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG EFFECT; ELECTRIC POTENTIAL; HUMAN; HYPERALGESIA; HYPERSENSITIVITY; IMMOBILIZATION STRESS; INFLAMMATION; INTESTINE MUCOSA PERMEABILITY; INTESTINE SECRETION; INTESTINE TRANSIT TIME; IRRITABLE COLON; NATRIURESIS; PRIORITY JOURNAL; PROTEIN FAMILY; REVIEW; STRESS; VISCERAL PAIN;

ANIMALS; CLINICAL TRIALS AS TOPIC; COLON; CONSTIPATION; HUMANS; IRRITABLE BOWEL SYNDROME; PEPTIDES; RATS;

EID: 76349111067     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2009.01465.x     Document Type: Review

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