Stereoelectronic and steric effects in side chains preorganize a protein main chain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 2, 2010, Pages 559-564

  Shoulders, Matthew D ^a   Satyshur, Kenneth A ^a   Forest, Katrina T ^a   Raines, Ronald T ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Collagen triple helix; Nonnatural amino acid; Preorganization; Protein stability; X ray crystallography

Indexed keywords

4 FLUOROPROLINE; 4 METHYLPROLINE; COLLAGEN; PROLINE; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; ENTROPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE; STEREOCHEMISTRY; STEREOSPECIFICITY;

AMINO ACID SEQUENCE; COLLAGEN; CRYSTALLOGRAPHY, X-RAY; DRUG STABILITY; ELECTRONICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROLINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; SOLUBILITY; STEREOISOMERISM;

EID: 76249128181     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909592107     Document Type: Article

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