-
1
-
-
76249101760
-
SEER Cancer Statistics Review, 1975-2006. Bethesda, Md: National Cancer Institute
-
Horner MJ, Ries LAG, Krapcho M, et al, eds, Available at:, Accessed on June 15, 2009
-
Horner MJ, Ries LAG, Krapcho M, et al, eds. SEER Cancer Statistics Review, 1975-2006. Bethesda, Md: National Cancer Institute. Based on the November 2008 SEER data submission; posted to the SEER website, 2009. Available at: http://info.cancerresearch.uk.org/cancerstats/types/kidney/incidence/. Accessed on June 15, 2009.
-
(2009)
Based on the November 2008 SEER data submission; posted to the SEER website
-
-
-
2
-
-
84880324406
-
-
Cancer Research UK, London, United Kingdom: Cancer Research UK;
-
Cancer Research UK. UK Kidney Cancer Incidence Statistics, 2009. London, United Kingdom: Cancer Research UK; 2009.
-
(2009)
UK Kidney Cancer Incidence Statistics, 2009
-
-
-
4
-
-
33645763970
-
WHO classification of the renal tumors of the adults
-
Lopez-Beltran A, Scarpelli M, Montironi R, Kirkali Z. 2004 WHO classification of the renal tumors of the adults. Eur Urol. 2006;49:798-805.
-
(2004)
Eur Urol
, vol.2006
, Issue.49
, pp. 798-805
-
-
Lopez-Beltran, A.1
Scarpelli, M.2
Montironi, R.3
Kirkali, Z.4
-
5
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
Hollstein M, Rice K, Greenblatt MS, et al. Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res. 1994;22:3551-3555.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
-
6
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D, Li FP, Strong LC, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science. 1990;250:1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
-
7
-
-
0028823020
-
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature. 1995;378:203-206.
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature. 1995;378:203-206.
-
-
-
-
9
-
-
0030860911
-
Repression of p53-mediated transcription by MDM2: A dual mechanism
-
Thut CJ, Goodrich JA, Tjian R. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev. 1997;11:1974-1986.
-
(1997)
Genes Dev
, vol.11
, pp. 1974-1986
-
-
Thut, C.J.1
Goodrich, J.A.2
Tjian, R.3
-
11
-
-
0034708458
-
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
-
Fang S, Jensen JP, Ludwig RL, Vousden KH, Weissman AM. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J Biol Chem. 2000;275: 8945-8951.
-
(2000)
J Biol Chem
, vol.275
, pp. 8945-8951
-
-
Fang, S.1
Jensen, J.P.2
Ludwig, R.L.3
Vousden, K.H.4
Weissman, A.M.5
-
12
-
-
33749188859
-
MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation
-
Yang JY, Zong CS, Xia W, et al. MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation. Mol Cell Biol. 2006;26:7269-7282.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7269-7282
-
-
Yang, J.Y.1
Zong, C.S.2
Xia, W.3
-
13
-
-
0036157247
-
Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods
-
Lu ML, Wikman F, Orntoft TF, et al. Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods. Clin Cancer Res. 2002;8:171-179.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 171-179
-
-
Lu, M.L.1
Wikman, F.2
Orntoft, T.F.3
-
14
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman CE, Lim DS, Cimprich KA, et al. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science. 1998;281:1677-1679.
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
-
15
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
Bode AM, Dong Z. Post-translational modification of p53 in tumorigenesis. Nat Rev Cancer. 2004;4:793-805.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
16
-
-
27644590943
-
Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry
-
Nenutil R, Smardova J, Pavlova S, et al. Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry. J Pathol. 2005; 207:251-259.
-
(2005)
J Pathol
, vol.207
, pp. 251-259
-
-
Nenutil, R.1
Smardova, J.2
Pavlova, S.3
-
17
-
-
15244362062
-
P53 abnormalities and outcomes in colorectal cancer: A systematic review
-
Munro AJ, Lain S, Lane DP. P53 abnormalities and outcomes in colorectal cancer: a systematic review. Br J Cancer. 2005;92:434-444.
-
(2005)
Br J Cancer
, vol.92
, pp. 434-444
-
-
Munro, A.J.1
Lain, S.2
Lane, D.P.3
-
18
-
-
2342461756
-
To die or not to die: How does p53 decide?
-
Slee EA, O'Connor DJ, Lu X. To die or not to die: how does p53 decide? Oncogene. 2004;23:2809-2818.
-
(2004)
Oncogene
, vol.23
, pp. 2809-2818
-
-
Slee, E.A.1
O'Connor, D.J.2
Lu, X.3
-
19
-
-
0030460978
-
The p53 response to ionising radiation in adult and developing murine tissues
-
MacCallum DE, Hupp TR, Midgley CA, et al. The p53 response to ionising radiation in adult and developing murine tissues. Oncogene. 1996;13:2575-2587.
-
(1996)
Oncogene
, vol.13
, pp. 2575-2587
-
-
MacCallum, D.E.1
Hupp, T.R.2
Midgley, C.A.3
-
20
-
-
0842332406
-
Dynamics of the p53-Mdm2 feedback loop in individual cells
-
Lahav G, Rosenfeld N, Sigal A, et al. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet. 2004;36:147-150.
-
(2004)
Nat Genet
, vol.36
, pp. 147-150
-
-
Lahav, G.1
Rosenfeld, N.2
Sigal, A.3
-
21
-
-
1542615083
-
p53 pathway in renal cell carcinoma is repressed by a dominant mechanism
-
Gurova KV, Hill JE, Razorenova OV, Chumakov PM, Gudkov AV. p53 pathway in renal cell carcinoma is repressed by a dominant mechanism. Cancer Res. 2004; 64:1951-1958.
-
(2004)
Cancer Res
, vol.64
, pp. 1951-1958
-
-
Gurova, K.V.1
Hill, J.E.2
Razorenova, O.V.3
Chumakov, P.M.4
Gudkov, A.V.5
-
22
-
-
23044508514
-
p53 regulation and function in renal cell carcinoma
-
Warburton HE, Brady M, Vlatkovic N, Linehan WM, Parsons K, Boyd MT. p53 regulation and function in renal cell carcinoma. Cancer Res. 2005;65:6498-6503.
-
(2005)
Cancer Res
, vol.65
, pp. 6498-6503
-
-
Warburton, H.E.1
Brady, M.2
Vlatkovic, N.3
Linehan, W.M.4
Parsons, K.5
Boyd, M.T.6
-
23
-
-
39049165830
-
Regulation of angiogenic factors by HDM2 in renal cell carcinoma
-
Carroll VA, Ashcroft M. Regulation of angiogenic factors by HDM2 in renal cell carcinoma. Cancer Res. 2008; 68:545-552.
-
(2008)
Cancer Res
, vol.68
, pp. 545-552
-
-
Carroll, V.A.1
Ashcroft, M.2
-
24
-
-
64549154074
-
Molecular signatures of localized clear cell renal cell carcinoma to predict disease-free survival after nephrectomy
-
Klatte T, Seligson DB, LaRochelle J, et al. Molecular signatures of localized clear cell renal cell carcinoma to predict disease-free survival after nephrectomy. Cancer Epidemiol Biomarkers Prev. 2009;18:894-900.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 894-900
-
-
Klatte, T.1
Seligson, D.B.2
LaRochelle, J.3
-
25
-
-
45449099580
-
Differential expression of prognostic markers in histological subtypes of papillary renal cell carcinoma
-
Perret AG, Clemencon A, Li G, Tostain J, Peoc'h M. Differential expression of prognostic markers in histological subtypes of papillary renal cell carcinoma. BJU Int. 2008;102:183-187.
-
(2008)
BJU Int
, vol.102
, pp. 183-187
-
-
Perret, A.G.1
Clemencon, A.2
Li, G.3
Tostain, J.4
Peoc'h, M.5
-
26
-
-
34247637684
-
Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma
-
Phuoc NB, Ehara H, Gotoh T, et al. Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma. Urology. 2007; 69:843-848.
-
(2007)
Urology
, vol.69
, pp. 843-848
-
-
Phuoc, N.B.1
Ehara, H.2
Gotoh, T.3
-
27
-
-
33750726054
-
The association of immunoreactive p53 and Ki-67 with T-stage, grade, occurrence of metastases and survival in renal cell carcinoma
-
Kankuri M, Soderstrom KO, Pelliniemi TT, Vahlberg T, Pyrhonen S, Salminen E. The association of immunoreactive p53 and Ki-67 with T-stage, grade, occurrence of metastases and survival in renal cell carcinoma. Anticancer Res. 2006;26(5B):3825-3833.
-
(2006)
Anticancer Res
, vol.26
, Issue.5 B
, pp. 3825-3833
-
-
Kankuri, M.1
Soderstrom, K.O.2
Pelliniemi, T.T.3
Vahlberg, T.4
Pyrhonen, S.5
Salminen, E.6
-
28
-
-
25844478044
-
Prognostic significance of ploidy, MIB-1 proliferation marker, and p53 in renal cell carcinoma
-
Kramer BA, Gao X, Davis M, Hall M, Holzbeierlein J, Tawfik O. Prognostic significance of ploidy, MIB-1 proliferation marker, and p53 in renal cell carcinoma. J Am Coll Surg. 2005;201:565-570.
-
(2005)
J Am Coll Surg
, vol.201
, pp. 565-570
-
-
Kramer, B.A.1
Gao, X.2
Davis, M.3
Hall, M.4
Holzbeierlein, J.5
Tawfik, O.6
-
29
-
-
14144249315
-
The pT1a and pT1b category subdivision in renal cell carcinoma: Is it reflected by differences in tumour biology?
-
Langner C, Ratschek M, Rehak P, Tsybrovskyy O, Zigeuner R. The pT1a and pT1b category subdivision in renal cell carcinoma: is it reflected by differences in tumour biology? BJU Int. 2005;95:310-314.
-
(2005)
BJU Int
, vol.95
, pp. 310-314
-
-
Langner, C.1
Ratschek, M.2
Rehak, P.3
Tsybrovskyy, O.4
Zigeuner, R.5
-
30
-
-
14944358654
-
Cyclooxygenase-2 and p53 expression as prognostic indicators in conventional renal cell carcinoma
-
Cho DS, Joo HJ, Oh DK, et al. Cyclooxygenase-2 and p53 expression as prognostic indicators in conventional renal cell carcinoma. Yonsei Med J. 2005;46:133-140.
-
(2005)
Yonsei Med J
, vol.46
, pp. 133-140
-
-
Cho, D.S.1
Joo, H.J.2
Oh, D.K.3
-
31
-
-
13744253120
-
p53 is an independent predictor of tumor recurrence and progression after nephrectomy in patients with localized renal cell carcinoma
-
Shvarts O, Seligson D, Lam J, et al. p53 is an independent predictor of tumor recurrence and progression after nephrectomy in patients with localized renal cell carcinoma. J Urol. 2005;173:725-728.
-
(2005)
J Urol
, vol.173
, pp. 725-728
-
-
Shvarts, O.1
Seligson, D.2
Lam, J.3
-
32
-
-
14944365551
-
Expression of p53 oncoprotein and bcl-2 in renal cell carcinoma
-
Uzunlar AK, Sahin H, Yilmaz F, Ozekinci S. Expression of p53 oncoprotein and bcl-2 in renal cell carcinoma. Saudi Med J. 2005;26:37-41.
-
(2005)
Saudi Med J
, vol.26
, pp. 37-41
-
-
Uzunlar, A.K.1
Sahin, H.2
Yilmaz, F.3
Ozekinci, S.4
-
33
-
-
1842789760
-
Value of p53 as a prognostic marker in histologic subtypes of renal cell carcinoma: A systematic analysis of primary and metastatic tumor tissue
-
Zigeuner R, Ratschek M, Rehak P, Schips L, Langner C. Value of p53 as a prognostic marker in histologic subtypes of renal cell carcinoma: a systematic analysis of primary and metastatic tumor tissue. Urology. 2004;63: 651-655.
-
(2004)
Urology
, vol.63
, pp. 651-655
-
-
Zigeuner, R.1
Ratschek, M.2
Rehak, P.3
Schips, L.4
Langner, C.5
-
34
-
-
4143060340
-
Using protein expressions to predict survival in clear cell renal carcinoma
-
Kim HL, Seligson D, Liu X, et al. Using protein expressions to predict survival in clear cell renal carcinoma. Clin Cancer Res. 2004;10:5464-5471.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5464-5471
-
-
Kim, H.L.1
Seligson, D.2
Liu, X.3
-
35
-
-
0036129145
-
Clinical significance of p53, mdm2, and bcl-2 proteins in renal cell carcinoma
-
Uchida T, Gao JP, Wang C, et al. Clinical significance of p53, mdm2, and bcl-2 proteins in renal cell carcinoma. Urology. 2002;59:615-620.
-
(2002)
Urology
, vol.59
, pp. 615-620
-
-
Uchida, T.1
Gao, J.P.2
Wang, C.3
-
36
-
-
0035141999
-
p53 immunoreactivity correlates with Ki-67 and bcl-2 expression in renal cell carcinoma
-
Olumi AF, Weidner N, Presti JC. p53 immunoreactivity correlates with Ki-67 and bcl-2 expression in renal cell carcinoma. Urol Oncol. 2001;6:63-67.
-
(2001)
Urol Oncol
, vol.6
, pp. 63-67
-
-
Olumi, A.F.1
Weidner, N.2
Presti, J.C.3
-
37
-
-
0035091293
-
p53 expression in correlation to clinical outcome in patients with renal cell carcinoma
-
Ljungberg B, Bozoky B, Kovacs G, et al. p53 expression in correlation to clinical outcome in patients with renal cell carcinoma. Scand J Urol Nephrol. 2001;35:15-20.
-
(2001)
Scand J Urol Nephrol
, vol.35
, pp. 15-20
-
-
Ljungberg, B.1
Bozoky, B.2
Kovacs, G.3
-
38
-
-
0035104991
-
P53 mutations and other prognostic factors of renal cell carcinoma
-
Girgin C, Tarhan H, Hekimgil M, Sezer A, Gurel G. P53 mutations and other prognostic factors of renal cell carcinoma. Urol Int. 2001;66:78-83.
-
(2001)
Urol Int
, vol.66
, pp. 78-83
-
-
Girgin, C.1
Tarhan, H.2
Hekimgil, M.3
Sezer, A.4
Gurel, G.5
-
39
-
-
0034026143
-
mdm2 expression as a prognostic indicator in clear cell renal cell carcinoma: Comparison with p53 overexpression and clinicopathological parameters
-
Haitel A, Wiener HG, Baethge U, Marberger M, Susani M. mdm2 expression as a prognostic indicator in clear cell renal cell carcinoma: comparison with p53 overexpression and clinicopathological parameters. Clin Cancer Res. 2000; 6:1840-1844.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1840-1844
-
-
Haitel, A.1
Wiener, H.G.2
Baethge, U.3
Marberger, M.4
Susani, M.5
-
40
-
-
0034114740
-
Value of immunohistochemical Ki-67 and p53 determinations as predictive factors of outcome in renal cell carcinoma
-
Rioux-Leclercq N, Turlin B, Bansard J, et al. Value of immunohistochemical Ki-67 and p53 determinations as predictive factors of outcome in renal cell carcinoma. Urology. 2000;55:501-505.
-
(2000)
Urology
, vol.55
, pp. 501-505
-
-
Rioux-Leclercq, N.1
Turlin, B.2
Bansard, J.3
-
41
-
-
0033015616
-
Expression of bcl-2, p53 oncoprotein, and proliferating cell nuclear antigen in renal cell carcinoma
-
Sejima T, Miyagawa I. Expression of bcl-2, p53 oncoprotein, and proliferating cell nuclear antigen in renal cell carcinoma. Eur Urol. 1999;35:242-248.
-
(1999)
Eur Urol
, vol.35
, pp. 242-248
-
-
Sejima, T.1
Miyagawa, I.2
-
42
-
-
0032101601
-
P53, bcl-2, and Bax expression in renal cell carcinoma
-
Vasavada SP, Novick AC, Williams BR. P53, bcl-2, and Bax expression in renal cell carcinoma. Urology. 1998; 51: 1057-1061.
-
(1998)
Urology
, vol.51
, pp. 1057-1061
-
-
Vasavada, S.P.1
Novick, A.C.2
Williams, B.R.3
-
43
-
-
0031435603
-
Nuclear p53 overexpression in bladder, prostate, and renal carcinomas
-
Sinik Z, Alkibay T, Ataoglu O, et al. Nuclear p53 overexpression in bladder, prostate, and renal carcinomas. Int J Urol. 1997;4:546-551.
-
(1997)
Int J Urol
, vol.4
, pp. 546-551
-
-
Sinik, Z.1
Alkibay, T.2
Ataoglu, O.3
-
44
-
-
0030877698
-
Value of p53 expression, cellular proliferation, and DNA content as prognostic indicators in renal cell carcinoma
-
Papadopoulos I, Rudolph P, Weichert-Jacobsen K. Value of p53 expression, cellular proliferation, and DNA content as prognostic indicators in renal cell carcinoma. Eur Urol. 1997;32:110-117.
-
(1997)
Eur Urol
, vol.32
, pp. 110-117
-
-
Papadopoulos, I.1
Rudolph, P.2
Weichert-Jacobsen, K.3
-
46
-
-
0030695994
-
Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma
-
Gelb AB, Sudilovsky D, Wu CD, Weiss LM, Medeiros LJ. Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma. Cancer. 1997;80:1768-1775.
-
(1997)
Cancer
, vol.80
, pp. 1768-1775
-
-
Gelb, A.B.1
Sudilovsky, D.2
Wu, C.D.3
Weiss, L.M.4
Medeiros, L.J.5
-
47
-
-
0031034067
-
Clinical significance of immunohistochemically detectable p53 protein in renal cell carcinoma
-
Shiina H, Igawa M, Urakami S, Shirakawa H, Ishibe T, Kawanishi M. Clinical significance of immunohistochemically detectable p53 protein in renal cell carcinoma. Eur Urol. 1997;31:73-80.
-
(1997)
Eur Urol
, vol.31
, pp. 73-80
-
-
Shiina, H.1
Igawa, M.2
Urakami, S.3
Shirakawa, H.4
Ishibe, T.5
Kawanishi, M.6
-
48
-
-
0030893002
-
p53 protein expression but not mdm-2 protein expression is associated with rapid tumor cell proliferation and prognosis in renal cell carcinoma
-
Moch H, Sauter G, Gasser TC, et al. p53 protein expression but not mdm-2 protein expression is associated with rapid tumor cell proliferation and prognosis in renal cell carcinoma. Urol Res. 1997;25(suppl 1):S25-S30.
-
(1997)
Urol Res
, vol.25
, Issue.SUPPL. 1
-
-
Moch, H.1
Sauter, G.2
Gasser, T.C.3
-
49
-
-
0030513772
-
Expression of p53 and bcl-2 in primary locally confined renal cell carcinomas: No evidence for prognostic significance
-
Hofmockel G, Wittmann A, Dammrich J, Bassukas ID. Expression of p53 and bcl-2 in primary locally confined renal cell carcinomas: no evidence for prognostic significance. Anticancer Res. 1996;16(6B):3807-3811.
-
(1996)
Anticancer Res
, vol.16
, Issue.6 B
, pp. 3807-3811
-
-
Hofmockel, G.1
Wittmann, A.2
Dammrich, J.3
Bassukas, I.D.4
-
50
-
-
0029116583
-
Elevated content of p53 protein in the absence of p53 gene mutations as a possible prognostic marker for human renal cell tumors
-
Chemeris G, Loktinov A, Rempel A, Schwarz M, Bannasch P. Elevated content of p53 protein in the absence of p53 gene mutations as a possible prognostic marker for human renal cell tumors. Virchows Arch. 1995;426:563-569.
-
(1995)
Virchows Arch
, vol.426
, pp. 563-569
-
-
Chemeris, G.1
Loktinov, A.2
Rempel, A.3
Schwarz, M.4
Bannasch, P.5
-
51
-
-
0028344419
-
Expression of proliferating cell nuclear antigen (PC10), p53 protein and c-erbB-2 in renal adenocarcinoma
-
Lipponen P, Eskelinen M, Hietala K, Syrjanen K, Gambetta RA. Expression of proliferating cell nuclear antigen (PC10), p53 protein and c-erbB-2 in renal adenocarcinoma. Int J Cancer. 1994;57:275-280.
-
(1994)
Int J Cancer
, vol.57
, pp. 275-280
-
-
Lipponen, P.1
Eskelinen, M.2
Hietala, K.3
Syrjanen, K.4
Gambetta, R.A.5
-
52
-
-
0028075573
-
Proliferating cell nuclear antigen but not p53 or human papillomavirus DNA correlates with advanced clinical stage in renal cell carcinoma
-
Kamel D, Turpeenniemi-Hujanen T, Vahakangas K, Paakko P, Soini Y. Proliferating cell nuclear antigen but not p53 or human papillomavirus DNA correlates with advanced clinical stage in renal cell carcinoma. Histopathology. 1994;25:339-347.
-
(1994)
Histopathology
, vol.25
, pp. 339-347
-
-
Kamel, D.1
Turpeenniemi-Hujanen, T.2
Vahakangas, K.3
Paakko, P.4
Soini, Y.5
-
53
-
-
0028224804
-
Prognostic factors in renal-cell carcinoma: Immunohistochemical detection of p53 protein versus clinico-pathological parameters
-
Bot FJ, Godschalk JC, Krishnadath KK, van der Kwast TH, Bosman FT. Prognostic factors in renal-cell carcinoma: immunohistochemical detection of p53 protein versus clinico-pathological parameters. Int J Cancer. 1994; 57:634-637.
-
(1994)
Int J Cancer
, vol.57
, pp. 634-637
-
-
Bot, F.J.1
Godschalk, J.C.2
Krishnadath, K.K.3
van der Kwast, T.H.4
Bosman, F.T.5
-
54
-
-
0027942884
-
Association of immunohistochemical staining for p53 with metastatic progression and poor survival in patients with renal cell carcinoma
-
Uhlman DL, Nguyen PL, Manivel JC, et al. Association of immunohistochemical staining for p53 with metastatic progression and poor survival in patients with renal cell carcinoma. J Natl Cancer Inst. 1994;86:1470-1475.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1470-1475
-
-
Uhlman, D.L.1
Nguyen, P.L.2
Manivel, J.C.3
-
55
-
-
77953440105
-
-
Boyd MT, Vlatkovic N. p53: a molecular marker for the detection of cancer. Expert Opin Med Diagn. 2008;2:1013-1024.
-
Boyd MT, Vlatkovic N. p53: a molecular marker for the detection of cancer. Expert Opin Med Diagn. 2008;2:1013-1024.
-
-
-
-
56
-
-
38149054906
-
Does the nonsense-mediated mRNA decay mechanism prevent the synthesis of truncated BRCA1, CHK2, and p53 proteins?
-
Anczukow O, Ware MD, Buisson M, et al. Does the nonsense-mediated mRNA decay mechanism prevent the synthesis of truncated BRCA1, CHK2, and p53 proteins? Hum Mutat. 2008;29:65-73.
-
(2008)
Hum Mutat
, vol.29
, pp. 65-73
-
-
Anczukow, O.1
Ware, M.D.2
Buisson, M.3
-
57
-
-
37349055876
-
TP53 mutations and survival in squamous-cell carcinoma of the head and neck
-
Poeta ML, Manola J, Goldwasser MA, et al. TP53 mutations and survival in squamous-cell carcinoma of the head and neck. N Engl J Med. 2007;357:2552-2561.
-
(2007)
N Engl J Med
, vol.357
, pp. 2552-2561
-
-
Poeta, M.L.1
Manola, J.2
Goldwasser, M.A.3
-
58
-
-
33846490110
-
Mutations in BHD and TP53 genes, but not in HNF1beta gene, in a large series of sporadic chromophobe renal cell carcinoma
-
Gad S, Lefevre SH, Khoo SK, et al. Mutations in BHD and TP53 genes, but not in HNF1beta gene, in a large series of sporadic chromophobe renal cell carcinoma. Br J Cancer. 2007;96:336-340.
-
(2007)
Br J Cancer
, vol.96
, pp. 336-340
-
-
Gad, S.1
Lefevre, S.H.2
Khoo, S.K.3
-
59
-
-
0033094077
-
Infrequent alteration of p53 pathway in metastatic renal cell carcinoma
-
Kawasaki T, Bilim V, Takahashi K, Tomita Y. Infrequent alteration of p53 pathway in metastatic renal cell carcinoma. Oncol Rep. 1999;6:329-333.
-
(1999)
Oncol Rep
, vol.6
, pp. 329-333
-
-
Kawasaki, T.1
Bilim, V.2
Takahashi, K.3
Tomita, Y.4
-
60
-
-
0031038176
-
Mutation of the p53 tumour suppressor gene occurs preferentially in the chromophobe type of renal cell tumour
-
Contractor H, Zariwala M, Bugert P, Zeisler J, Kovacs G. Mutation of the p53 tumour suppressor gene occurs preferentially in the chromophobe type of renal cell tumour. J Pathol. 1997;181:136-139.
-
(1997)
J Pathol
, vol.181
, pp. 136-139
-
-
Contractor, H.1
Zariwala, M.2
Bugert, P.3
Zeisler, J.4
Kovacs, G.5
-
61
-
-
0031938641
-
A novel p53 mutation hotspot at codon 132 (AAG→AGG) in human renal cancer
-
Dahiya R, Deng G, Selph C, Carroll P, Presti J Jr. A novel p53 mutation hotspot at codon 132 (AAG→AGG) in human renal cancer. Biochem Mol Biol Int. 1998;44:407-415.
-
(1998)
Biochem Mol Biol Int
, vol.44
, pp. 407-415
-
-
Dahiya, R.1
Deng, G.2
Selph, C.3
Carroll, P.4
Presti Jr, J.5
-
62
-
-
0029902408
-
Chromosomal findings and p53-mutation analysis in chromophilic renal-cell carcinomas
-
Dijkhuizen T, Van den Berg E, Van den Berg A, et al. Chromosomal findings and p53-mutation analysis in chromophilic renal-cell carcinomas. Int J Cancer. 1996;68:47-50.
-
(1996)
Int J Cancer
, vol.68
, pp. 47-50
-
-
Dijkhuizen, T.1
Van den Berg, E.2
Van den Berg, A.3
-
63
-
-
0028898538
-
Mutations of the p53 gene and p53 protein overexpression are associated with sarcomatoid transformation in renal cell carcinomas
-
Oda H, Nakatsuru Y, Ishikawa T. Mutations of the p53 gene and p53 protein overexpression are associated with sarcomatoid transformation in renal cell carcinomas. Cancer Res. 1995;55:658-662.
-
(1995)
Cancer Res
, vol.55
, pp. 658-662
-
-
Oda, H.1
Nakatsuru, Y.2
Ishikawa, T.3
-
64
-
-
0029588556
-
Detection of p53 gene alteration in renal-cell cancer by micropreparation techniques of tumor specimens
-
Kuczyk MA, Serth J, Bokemeyer C, et al. Detection of p53 gene alteration in renal-cell cancer by micropreparation techniques of tumor specimens. Int J Cancer. 1995;64:399-406.
-
(1995)
Int J Cancer
, vol.64
, pp. 399-406
-
-
Kuczyk, M.A.1
Serth, J.2
Bokemeyer, C.3
-
65
-
-
0027998416
-
Genomic instability of microsatellite repeats and mutations of H-, K-, and N-ras, and p53 genes in renal cell carcinoma
-
Uchida T, Wada C, Wang C, Egawa S, Ohtani H, Koshiba K. Genomic instability of microsatellite repeats and mutations of H-, K-, and N-ras, and p53 genes in renal cell carcinoma. Cancer Res. 1994;54:3682-3685.
-
(1994)
Cancer Res
, vol.54
, pp. 3682-3685
-
-
Uchida, T.1
Wada, C.2
Wang, C.3
Egawa, S.4
Ohtani, H.5
Koshiba, K.6
-
66
-
-
0028276903
-
Polymerase chain reaction-single strand conformation polymorphism analysis of the p53 gene in paraffin-embedded surgical material from human renal cell carcinomas
-
Kikuchi Y, Kishi T, Suzuki M, Furusato M, Aizawa S. Polymerase chain reaction-single strand conformation polymorphism analysis of the p53 gene in paraffin-embedded surgical material from human renal cell carcinomas. Virchows Arch. 1994;424:229-233.
-
(1994)
Virchows Arch
, vol.424
, pp. 229-233
-
-
Kikuchi, Y.1
Kishi, T.2
Suzuki, M.3
Furusato, M.4
Aizawa, S.5
-
67
-
-
0028506828
-
p53 mutations and MDM-2 amplification in renal cell cancers
-
Imai Y, Strohmeyer TG, Fleischhacker M, Slamon DJ, Koeffler HP. p53 mutations and MDM-2 amplification in renal cell cancers. Mod Pathol. 1994;7:766-770.
-
(1994)
Mod Pathol
, vol.7
, pp. 766-770
-
-
Imai, Y.1
Strohmeyer, T.G.2
Fleischhacker, M.3
Slamon, D.J.4
Koeffler, H.P.5
-
68
-
-
0027282013
-
Chromosome 17p deletions and p53 mutations in renal cell carcinoma
-
Reiter RE, Anglard P, Liu S, Gnarra JR, Linehan WM. Chromosome 17p deletions and p53 mutations in renal cell carcinoma. Cancer Res. 1993;53:3092-3097.
-
(1993)
Cancer Res
, vol.53
, pp. 3092-3097
-
-
Reiter, R.E.1
Anglard, P.2
Liu, S.3
Gnarra, J.R.4
Linehan, W.M.5
-
69
-
-
0026534279
-
Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis
-
Suzuki Y, Tamura G, Satodate R, Fujioka T. Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis. Jpn J Cancer Res. 1992;83:233-235.
-
(1992)
Jpn J Cancer Res
, vol.83
, pp. 233-235
-
-
Suzuki, Y.1
Tamura, G.2
Satodate, R.3
Fujioka, T.4
-
70
-
-
0026984656
-
p53 gene mutation in primary human renal cell carcinoma
-
Torigoe S, Shuin T, Kubota Y, Horikoshi T, Danenberg K, Danenberg PV. p53 gene mutation in primary human renal cell carcinoma. Oncol Res. 1992;4:467-472.
-
(1992)
Oncol Res
, vol.4
, pp. 467-472
-
-
Torigoe, S.1
Shuin, T.2
Kubota, Y.3
Horikoshi, T.4
Danenberg, K.5
Danenberg, P.V.6
-
71
-
-
34248379012
-
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
-
Petitjean A, Mathe E, Kato S, et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat. 2007;28:622-629.
-
(2007)
Hum Mutat
, vol.28
, pp. 622-629
-
-
Petitjean, A.1
Mathe, E.2
Kato, S.3
-
72
-
-
0035751937
-
Assessing TP53 status in human tumours to evaluate clinical outcome
-
Soussi T, Beroud C. Assessing TP53 status in human tumours to evaluate clinical outcome. Nat Rev Cancer. 2001;1:233-240.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 233-240
-
-
Soussi, T.1
Beroud, C.2
-
73
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo C, Latres E, Drobnjak M, et al. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res. 1994;54:794-799.
-
(1994)
Cancer Res
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
-
74
-
-
34547220487
-
MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma
-
Hirata H, Hinoda Y, Kikuno N, et al. MDM2 SNP309 polymorphism as risk factor for susceptibility and poor prognosis in renal cell carcinoma. Clin Cancer Res. 2007;13:4123-4129.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4123-4129
-
-
Hirata, H.1
Hinoda, Y.2
Kikuno, N.3
-
75
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science. 2004;303:844-848.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
-
76
-
-
41649102468
-
Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
-
Shangary S, Qin D, McEachern D, et al. Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition. Proc Natl Acad Sci USA. 2008;105:3933-3938.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3933-3938
-
-
Shangary, S.1
Qin, D.2
McEachern, D.3
-
77
-
-
20444369867
-
Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells
-
Yang Y, Ludwig RL, Jensen JP, et al. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells. Cancer Cell. 2005;7:547-559.
-
(2005)
Cancer Cell
, vol.7
, pp. 547-559
-
-
Yang, Y.1
Ludwig, R.L.2
Jensen, J.P.3
-
79
-
-
61349141840
-
9-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-kappaB and p53 pathways
-
Guo C, Gasparian AV, Zhuang Z, et al. 9-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-kappaB and p53 pathways. Oncogene. 2009;28:1151-1161.
-
(2009)
Oncogene
, vol.28
, pp. 1151-1161
-
-
Guo, C.1
Gasparian, A.V.2
Zhuang, Z.3
-
80
-
-
60649103811
-
MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53
-
Enge M, Bao W, Hedstrom E, Jackson SP, Moumen A, Selivanova G. MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53. Cancer Cell. 2009;15:171-183.
-
(2009)
Cancer Cell
, vol.15
, pp. 171-183
-
-
Enge, M.1
Bao, W.2
Hedstrom, E.3
Jackson, S.P.4
Moumen, A.5
Selivanova, G.6
-
81
-
-
59549099511
-
Effect of renal cancer size on the prevalence of metastasis at diagnosis and mortality
-
discussion 1027
-
Nguyen MM, Gill IS. Effect of renal cancer size on the prevalence of metastasis at diagnosis and mortality. J Urol. 2009;181:1020-1027; discussion 1027.
-
(2009)
J Urol
, vol.181
, pp. 1020-1027
-
-
Nguyen, M.M.1
Gill, I.S.2
-
82
-
-
33645705685
-
Nonmetastatic renal-cell carcinoma: Is it really possible to define rational guidelines for post-treatment follow-up?
-
Rouviere O, Bouvier R, Negrier S, Badet L, Lyonnet D. Nonmetastatic renal-cell carcinoma: is it really possible to define rational guidelines for post-treatment follow-up? Nat Clin Pract Oncol. 2006;3:200-213.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 200-213
-
-
Rouviere, O.1
Bouvier, R.2
Negrier, S.3
Badet, L.4
Lyonnet, D.5
|