Induction of ROS, p38 MAP kinase and apoptosis via pulmonary toxic drugs

Biochip Journal

Volumn 3, Issue 4, 2009, Pages 306-315

  Song, Mee ^a   Kim, Youn Jung ^a   Ryu, Jae Chun ^a  

^a Korea Institute of Science and Technology   (South Korea)

Author keywords

Apoptosis; Drug; p38 MAPK; Pulmonary toxicity; ROS

Indexed keywords

EID: 76149097213     PISSN: 19760280     EISSN: 20927843     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Rosenow, E.C. Drug-induced pulmonary disease. Dis. Mon. 40, 253-310 (1994).
2. Ali, A. & Schmidt, M.F.J. Drug-Induced Pulmonary Toxicity. emedicine.medscape.com (2008).
3. Texada, J.C. & Singh, S.P. Radiology: Mcgraw-hill Specialty Board Review, 280-289 (2009).
4. Adamson, I.Y. Drug-induced pulmonary fibrosis. Environ. Health Perspect. 55, 25-36 (1984).
5. Herman, S., Zurgil, N. & Deutsch, M. Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines. Inflamm. Res. 54, 273-280 (2005).
6. Kim, Y.J., Song, M. & Ryu, J.C. Gene expression profiling of human bronchial epithelial (BEAS-2B) cells treated with nitrofurantoin, a pulmonary toxicant. Mol. & Cell. Toxicol. 5, 222-230 (2007).
7. Begriche, K., Igoudjil, A., Pessayre, D. & Fromenty, B. Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion 6, 1-28 (2006).
8. Pérez Martín, J.M., Fernández Freire, P., Labrador, V. & Hazen, M.J. Carbamazepine induces mitotic arrest in mammalian Vero cells. Mutat. Res. 637, 124-133 (2007).
9. Yoshikawa, Y., Hosomi, H., Fukami, T., Nakajima, M. & Yokoi, T. Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity. Toxicol. In Vitro 23, 1179-1187 (2009).
10. Hsu, P.C., Lan, J.L., Hsieh, T.Y., Jan, Y.J. & Huang, W.N. Methotrexate pneumonitis in a patient with rheumatoid arthritis. J. Microbiol. Immunol. Infect. 36, 137-140 (2003).
11. Turesson, C. & Matteson, E.L. Genetics of rheumatoid arthritis. Mayo. Clin. Proc. 81, 94-101 (2006).
12. Wilschut, F.A. et al. Recurrent respiratory distress associated with carbamazepine overdose. Eur. Respir. J. 10, 2163-2165 (1997).
13. Ozkan, M., Dweik, R.A. & Ahmad, M. Drug-induced lung disease. Cleve. Clin. J. Med. 68, 782-785, 789-795 (2001).
14. Azad, N., Rojanasakul, Y. & Vallyathan, V. Inflammation and lung cancer: roles of reactive oxygen/nitrogen species. J. Toxicol. Environ. Health B Crit. Rev. 11, 1-15.(2008).
15. Daba, M.H., El-Tahir, K.E., Al-Arifi, M.N. & Gubara, O.A. Drug-induced pulmonary fibrosis. Saudi. Med. J. 25, 700-706 (2004).
16. Hu, H. et al. Calpain-1 induces apoptosis in pulmonary microvascular endothelial cells under septic conditions. Microvasc. Res. 78, 33-39 (2009).
17. Mishra, A., Doyle, N.A. & Martin, W.J. 2cnd. Bleomycin-mediated pulmonary toxicity: evidence for a p53-mediated response. Am. J. Respir. Cell Mol. Biol. 22, 543-549 (2000).
18. Choi, I.S. et al. Amiodarone induces apoptosis in L-132 human lung epithelial cell line. Toxicol. Lett. 132, 47-55 (2002).
19. Mossman, B.T., Lounsbury, K.M. & Reddy, S.P. Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. Am. J. Respir. Cell Mol. Biol. 34, 666-669 (2006).
20. Higenbottam, T., Kuwano, K., Nemery, B. & Fujita, Y. Understanding the mechanisms of drug-associated interstitial lung disease. Br. J. Cancer. 91, S31-37 (2004).
21. Canal-Raffin, M. et al. Cytotoxicity of folpet fungi-cide on human bronchial epithelial cells. Toxicology 249, 160-166 (2008).
22. Park, J.H. et al. Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases. Oncol. Rep. 20, 379-384 (2008).
23. Harvilchuck, J.A., Pu, X., Klaunig, J.E. & Carlson, G.P. Indicators of oxidative stress and apoptosis in mouse whole lung and Clara cells following exposure to styrene and its metabolites. Toxicology 264, 171-178 (2009).
24. Sener, G., Ekşioǧlu-Demiralp, E., Cetiner, M., Ercan, F. & Yeǧen, B.C. Beta-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects. Eur. J. Pharmacol. 542, 170-178 (2006).
25. Dershwitz, M., Ts'ao, C.H. & Novak, R.F. Metabolic and morphologic effects of the antimicrobial agent nitrofurantoin on human erythrocytes in vitro. Biochem. Pharmacol. 34, 1963-1970 (1985).
26. Halici, Z. et al. Amiodarone has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced paw edema. Eur. J. Pharmacol. 566, 215-221 (2007).
27. Santos, N.A. et al. Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs. Toxicol. In Vitro 22, 1820-1824 (2008).
28. Kim, Y.J., Song, M. & Ryu, J.C. Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway. Toxicology 256, 183-190 (2009).
29. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63 (1983).
30. Tusher, V.G., Tibshirani, R., & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. U.S.A. 98, 5116-5121 (2001).