Amyloid and Tau accumulate in the brains of aged hydrocephalic rats

Brain Research

Volumn 1317, Issue , 2010, Pages 286-296

  Silverberg, Gerald D ^a   Miller, Miles C ^a   Machan, Jason T ^b   Johanson, Conrad E ^a   Caralopoulos, Ilias N ^a   Pascale, Crissey L ^a   Heile, Anna ^c   Klinge, Petra M ^a  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

^c INTERNATIONAL NEUROSCIENCE INSTITUTE   (Germany)

Author keywords

Amyloid; Clearance; CSF circulation; NPH; pTau

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; EPITOPE; FLUORESCENT DYE; KAOLIN; TAU PROTEIN;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN CORTEX; BRAIN NERVE CELL; CEREBROSPINAL FLUID; CLEARANCE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; NEUROCHEMISTRY; NONHUMAN; NORMOTENSIVE HYDROCEPHALUS; PARENCHYMA; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT;

AGING; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HYDROCEPHALUS, NORMAL PRESSURE; KAOLIN; MALE; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; TAU PROTEINS; TIME FACTORS;

ANIMALIA; RATTUS;

EID: 75849165166     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.12.065     Document Type: Article

References (50)

1. Augustinack J.C., Schneider A., Mandelkow E.M., and Hyman B.T. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol. (Berl) 103 (2002) 26-35
2. Bech R.A., Waldemar G., Gjerris F., Klinken L., and Juhler M. Shunting effects in patients with idiopathic normal pressure hydrocephalus; correlation with cerebral and leptomeningeal biopsy findings. Acta Neurochir. (Wien) 141 (1999) 633-639
3. Bell R.D., and Zlokovic B.V. Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol. 118 (2009) 103-113
4. Bell R.D., Sagare A.P., Friednab A.E., Bedi G.S., Holtzman D.M., Deane R., and Zlokovic B.V. Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system. J. Cereb. Blood Flow Metab. 27 (2006) 909-918
5. Boon A.J., Tans J.T., Delwel E.J., Egeler-Peerdeman S.M., Hanlo P.W., Wurzer J.A., and Hermans J. Does CSF outflow resistance predict the response to shunting in patients with normal pressure hydrocephalus?. Acta Neurochir. Suppl. (Wien) 71 (1998) 331-333
6. Brinker T., Beck H., Klinge P., Kischnik B., Oi S., and Samii M. Sinusoidal intrathecal infusion for assessment of CSF dynamics in kaolin-induced hydrocephalus. Acta Neurochir. (Wien) 140 (1998) 1069-1075
7. Busciglio J., Lorenzo A., Yeh J., and Yankner B.A. Beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron 14 (1995) 879-888
8. Clarke J., Thornell A., Corbett D., Soininen H., Hiltunen M., and Jolkkonen J. Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats. Eur. J. Neurosci. 26 (2007) 1845-1852
9. Davson H., and Oldendorf W.H. Symposium on membrane transport. Transport in the central nervous system. Proc. R. Soc. Med. 60 (1967) 326-329
10. De Felice F.G., Wu D., Lambert M.P., Fernandez S.J., Velasco P.T., Lacor P.N., Bigio E.H., Jerecic J., Acton P.J., Shughrue P.J., Chen-Dodson E., Kinney G.G., and Klein W.L. Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Abeta oligomers. Neurobiol. Aging 29 (2008) 1334-1347
11. Del Bigio M.R., Cardoso E.R., and Halliday W.C. Neuropathological changes in chronic adult hydrocephalus: cortical biopsies and autopsy findings. Can. J. Neurol. Sci. 24 (1997) 121-126
12. Deren K.E., Forsyth J., Abdullah O., Hsu F.W., Klinge P.M., Silverberg G.D., Johanson C.E., and McAllister J.P. Clearance of amyloid-beta in neonatal hydrocephalus. Cerebrospinal Fluid Res. 6 (2009) 4
13. Esler W.P., Stimson E.R., Jennings J.M., Ghilardi J.R., Mantyh P.W., and Maggio J.E. Zinc-induced aggregation of human and rat β-amyloid peptides in vitro. J. Neurochem. 66 (1996) 723-732
14. Fukumoto H., Tomita T., Matsunaga H., Ishibashi Y., Saido T.C., and Iwatsubo T. Primary cultures of neuronal and non-neuronal rat brain cells secrete similar proportions of amyloid β peptides ending at Aβ40 and Aβ42. NeuroReport 10 (1999) 2965-2969
15. Goedert M., Jakes R., Crowther R.A., Cohen P., Vanmechelen E., Vandermeeren M., and Cras P. Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. Biochem. J. 301 (1994) 871-877
16. Golomb J., Wisoff J., Miller D.C., Boksay I., Kluger A., Weiner H., Saltom J., and Graves W. Alzheimer's disease comorbidity in normal pressure hydrocephalus: prevalence and shunt response. J. Neurol. Neurosurg. Psychiatry 68 (2000) 778-781
17. Hakim S., and Adams R.D. The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics. J. Neurol. Sci. 2 (1965) 307-2327
18. Hochwald G.M., and Sahar A. Effect of spinal fluid pressure on cerebrospinal fluid formation. Exp. Neurol. 32 (1971) 30-40
19. Hochwald G.M., Nakamura S., and Camins M.B. The rat in experimental obstructive hydrocephalus. Z. Kinderchir. 34 (1981) 403-410
20. Iwata N., Tsubuki S., Takaki Y., Watanabe K., Sekiguchi M., Hosoki E., Kawashima-Morishima M., Lee H.J., Hama E., Sekine-Aizawa Y., and Saido T.C. Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition. Nat. Med. 6 (2000) 143-150
21. Kawamata T., Katayama Y., Tsuji N., and Nishimoto H. Metabolic derangements in interstitial brain edema with preserved blood flow: selective vulnerability of the hippocampal CA3 region in hydrocephalic rats. Acta Neurochir. Suppl. 86 (2000) 545-547
22. Klinge P.M., Samii A., Muhlendyck A., Visnyei K., Meyer G.J., Walter G.F., Silverberg G.D., and Brinker T. Cerebral hypoperfusion and delayed hippocampal response after induction of adult kaolin hydrocephalus. Stroke 34 (2003) 193-199
23. Klinge P., Mühlendyck A., Lee S., Ludemann W., Groos S., Samii M., and Brinker T. Temporal and regional profile of neuronal and glial cellular injury after induction of kaolin hydrocephalus. Acta Neurochir. Suppl. 81 (2002) 275-277
24. Klinge P.M., Samii A., Niesken S., Brinker T., and Silverberg G.D. Brain amyloid accumulation in aged rats with kaolin-induced hydrocephalus. NeuroReport 17 (2006) 657-660
25. Kondziella D., Ludemann W., Brinker T., Sletvold O., and Sonnewald U. Alterations in brain metabolism, CNS morphology and CSF dynamics in adult rats with kaolin-induced hydrocephalus. Brain Res. 927 (2002) 35-41
26. Kuchiwaki H., Nagasaka M., Inao S., and Sugita K. Progression of kaolin-induced hydrocephalus and changes in performance of operant tasks by rats. J. Neurol. Sci. 121 (1994) 32-38
27. Lecanu L., Greeson J., and Papadopoulos V. Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain. Pharmacology 76 (2006) 19-33
28. Li L., Zhang X., Yang D., Luo G., Chen S., and Le W. Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP. Neurobiol. Aging 30 (2009) 1091-1098
29. McKee A., Carreras I., Hossain L., Ryu H., Klein W.L., Oddo S., LaFerla F.M., Jenkins B.G., Kowall N.W., and Dedeoglu A. Ibuprophen reduces A-beta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain 1207 (2008) 225-236
30. Mizoroki T., Meshitsuka S., Maeda S., Murayama M., Sahara N., and Takashima A. Aluminum induces tau aggregation in vitro but not in vivo. J. Alzheimers Dis. 12 (2007) 313-315
31. Mudher A., and Lovestone S. Alzheimer's disease-do tauists and baptists finally shake hands?. Trends Neurosci. 25 (2002) 22-26
32. Nadler Y., Alexandrovich A., Grigoriatis N., Hartmann T., Rao K.S., Shohami E., and Stein R. Increased expression of the gamma-secretase components presenilin-1 and nicastrin in the activated astrocytes and microglia following traumatic brain injury. Glia 56 (2008) 552-567
33. Oddo S., Caccamo A., Tran L., Lambert M.P., Glabe C.G., Klein W.L., and LaFerla F.M. Temporal profile of amyloid-beta (A-beta) oligomerization in an in vivo model of Alzheimer disease. A link between A-beta and Tau pathology. J. Biol. Chem. 281 (2006) 1599-1604
34. Olsson A., Csajbok L., Ost M., Höglund K., Nylén K., Rosengren L., Nellgård B., and Blennow K. Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury. J. Neurol. 251 (2004) 870-876
35. Rodella L.F., Ricci F., Borsana E., Stacchiotti A., Foglio E., Favero G., Rezzani R., Mariani C., and Bianchi R. Aluminium exposure induces Alzheimer's disease-like histopathological alterations in mouse brain. Histol. Histopathol. 23 (2008) 433-439
36. Savolainen S., Paljarvi L., and Vapalahti M. Prevalence of Alzheimer's disease in patients investigated for presumed normal pressure hydrocephalus: a clinical and neuropathological study. Acta Neurochir. (Wien) 141 (1999) 849-853
37. 1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J. Clin. Invest. 106 (2000) 1489-1499
38. Shim I., Ha Y., Chung J.Y., Lee H.J., Yang K.H., and Chang J.W. Association of learning and memory impairments with changes in the septohippocampal cholinergic system in rats with kaolin-induced hydrocephalus. Neurosurgery 53 (2003) 416-425
39. Silverberg G.D. Normal pressure hydrocephalus (NPH): ischaemia, CSF stagnation or both. (editorial) Brain 127 (2004) 947-948
40. Silverberg G.D., Huhn S., Jaffee R.A., Chang S.D., Saul T., Heit G., Von Essen A., and Rubenstein E. Downregulation of cerebrospinal fluid production in patients with chronic hydrocephalus. J. Neurosurg. 97 (2002) 1271-1275
41. Silverberg G.D., Mayo M., Saul T., Rubenstein E., and McGuire D. Alzheimer's disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: a hypothesis. Lancet Neurol. 2 (2003) 506-511
42. Silverberg G.D., Caralopoulos I.N., Slone S.L., Miller M., Messier A., Kenney E., and Johanson C.E. Amyloid and Tau accumulation precede CSF production decline in normal aging (Abstract). Cerebrospinal Fluid Res. (2009) electronic publication 6(Suppl. 1):S38 (3 February 2009)
43. Silverberg, G.D., Miller, M.C., Messier, A.A., Majmudar, S., Machan, J.T., Donahue, J.E., Stopa, E.G., Johanson, C.E., 2010. Amyloid deposition and influx transporter expression at the blood-brain barrier increase in normal aging. J. Neuropathol. Exp. Neurol. 69, 98-108.
44. Snowdon D.A., Greiner L.H., Mortimer J.A., Riley K.P., Greiner P.A., and Markesbery W.R. Brain infarction and the clinical expression of Alzheimer's disease. JAMA 277 (1997) 813-817
45. 717 mutants). Science 264 (1994) 336-340
46. Van Den Heuval C., Thornton E., and Vink R. Traumatic brain injury and Alzheimer's disease: a review. Prog. Brain Res. 161 (2007) 303-316
47. Van Groen T., Puurunen K., Maki H.M., Sivenius J., and Jolkkonen J. Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus after transient occlusion of the middle cerebral artery in rats. Stroke 36 (2005) 1551-1556
48. Weller R.O. Pathology of cerebrospinal fluid and interstitial fluid of the CNS: significance for Alzheimer's disease, prion disorders and multiple sclerosis. J. Neuropathol. Exp. Neurol. 57 (1998) 885-894
49. Weller R.O., and Boche D. Nicoll JA. Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy. Acta Neuropathol. 118 (2009) 87-102
50. Xu G., Gonzales V., and Borchelt D. A[beta] deposition does not cause the aggregation of endogenous Tau in transgenic mice. Alzheimer Dis. Assoc. Disord. 16 (2002) 196-201