Functional evaluation of the role of reticuloendotheliosis virus long terminal repeat (LTR) integrated into the genome of a field strain of Marek's disease virus

Virology

Volumn 397, Issue 2, 2010, Pages 270-276

  Sun, Ai jun ^a   Xu, Xiao yun ^a   Petherbridge, Lawrence ^b   Zhao, Yu guang ^b   Nair, Venugopal ^b   Cui, Zhi zhong ^a  

^a SHANDONG AGRICULTURAL UNIVERSITY   (China)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

LTR; MDV; Pathogenesis; REV

Indexed keywords

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BIRD DISEASE; CONTROLLED STUDY; DELETION MUTANT; DNA SEQUENCE; GENE CONSTRUCT; GENE TRANSFER; GROWTH INHIBITION; LONG TERMINAL REPEAT; MARDIVIRUS; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETICULOENDOTHELIOSIS VIRUS; STRUCTURE ACTIVITY RELATION; VIRAL PHENOMENA AND FUNCTIONS; VIRUS GENOME; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; BIRDS; DNA, VIRAL; IMMUNOSUPPRESSION; MARDIVIRUS; MAREK DISEASE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; RECOMBINATION, GENETIC; RETICULOENDOTHELIOSIS VIRUS; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; TERMINAL REPEAT SEQUENCES;

AVES; GALLID HERPESVIRUS 2; RETICULOENDOTHELIOSIS VIRUS;

EID: 75749147917     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.11.017     Document Type: Article

References (29)

1. Adler H., Messerle M., and Koszinowski U.H. Cloning of herpesviral genomes as bacterial artificial chromosomes. Rev. Med. Virol. 13 2 (2003) 111-121
2. Baigent S.J., Petherbridge L.J., Smith L.P., Zhao Y., Chesters P.M., and Nair V.K. Herpesvirus of turkey reconstituted from bacterial artificial chromosome clones induces protection against Marek's disease. J. Gen. Virol. 87 Pt. 4 (2006) 769-776
3. Cui Z.Z., Lee L.F., Liu J.L., and Kung H.J. Structural analysis and transcriptional mapping of the Marek's disease virus gene encoding pp38, an antigen associated with transformed cells. J. Virol. 65 12 (1991) 6509-6515
4. Cui H., Wang Y., Shi X., Tong G., Lan D., He L., Qiu H., Liu C., and Wang M. Construction of Marek's disease virus serotype 814 strain as an infectious bacterial artificial chromosome. Sheng Wu Gong Cheng Xue Bao 24 4 (2008) 569-575
5. Cui H.Y., Wang Y.F., Shi X.M., An T.Q., Tong G.Z., Lan D.S., He L., Liu C.J., and Wang M. Construction of an infectious Marek's disease virus bacterial artificial chromosome and characterization of protection induced in chickens. J. Virol. Methods 156 1-2 (2009) 66-72
6. Datsenko K.A., and Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 97 12 (2000) 6640-6645
7. Davidson I., and Borenshtain R. In vivo events of retroviral long terminal repeat integration into Marek's disease virus in commercial poultry: detection of chimeric molecules as a marker. Avian. Dis. 45 1 (2001) 102-121
8. Isfort R., Jones D., Kost R., Witter R., and Kung H.J. Retrovirus insertion into herpesvirus in vitro and in vivo. Proc. Natl. Acad. Sci. U. S. A. 89 3 (1992) 991-995
9. Isfort R.J., Qian Z., Jones D., Silva R.F., Witter R., and Kung H.J. Integration of multiple chicken retroviruses into multiple chicken herpesviruses: herpesviral gD as a common target of integration. Virology 203 1 (1994) 125-133
10. Jones D., Brunovskis P., Witter R., and Kung H.J. Retroviral insertional activation in a herpesvirus: transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus clone. J. Virol. 70 4 (1996) 2460-2467
11. Jones D., Isfort R., Witter R., Kost R., and Kung H.J. Retroviral insertions into a herpesvirus are clustered at the junctions of the short repeat and short unique sequences. Proc. Natl. Acad. Sci. U. S. A. 90 9 (1993) 3855-3859
12. Kost R., Jones D., Isfort R., Witter R., and Kung H.J. Retrovirus insertion into herpesvirus: characterization of a Marek's disease virus harboring a solo LTR. Virology 192 1 (1993) 161-169
13. Lee L.F., Liu X., and Witter R.L. Monoclonal antibodies with specificity for three different serotypes of Marek's disease viruses in chickens. J. Immunol. 130 2 (1983) 1003-1006
14. Lee L.F., Wu P., Sui D., Ren D., Kamil J., Kung H.J., and Witter R.L. The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus. Proc. Natl. Acad. Sci. U. S. A. 97 11 (2000) 6091-6096
15. Lupiani B., Lee L.F., Cui X., Gimeno I., Anderson A., Morgan R.W., Silva R.F., Witter R.L., Kung H.J., and Reddy S.M. Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication. Proc. Natl. Acad. Sci. U. S. A. 101 32 (2004) 11815-11820
16. Muyrers J.P., Zhang Y., Testa G., and Stewart A.F. Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res. 27 6 (1999) 1555-1557
17. Narayanan K.R., Williamson Y., Zhang A., Stewart F., and Ioannou P.A. Efficient and precise engineering of a 200 kb beta-globin human bacterial artificial chromosome in E. coli DH10B using an inducible homologous recombination system. Gene Ther. 6 (1999) 442-447
18. Petherbridge L., Howes K., Baigent S.J., Sacco M.A., Evans S., Osterrieder N., and Nair V. Replication-competent bacterial artificial chromosomes of Marek's disease virus: novel tools for generation of molecularly defined herpesvirus vaccines. J. Virol. 77 16 (2003) 8712-8718
19. Petherbridge L., Brown A.C., Baigent S.J., Howes K., Sacco M.A., Osterrieder N., and Nair V.K. Oncogenicity of virulent Marek's disease virus cloned as bacterial artificial chromosomes. J. Virol. 78 23 (2004) 13376-13380
20. Petherbridge L., Xu H., Zhao Y., Smith L.P., Simpson J., Baigent S., and Nair V. Cloning of Gallid herpesvirus 3 (Marek's disease virus serotype-2) genome as infectious bacterial artificial chromosomes for analysis of viral gene functions. J. Virol. Methods 158 1-2 (2009) 11-17
21. Reddy S.M., Lupiani B., Gimeno I., Silva R.F., Lee L.F., and Witter R.L. Rescue of a pathogenic Marek's disease virus with overlapping cosmid DNAs: use of a pp38 mutant to validate the technology for the study of gene function. Proc. Natl. Acad. Sci. U. S. A. 99 10 (2002) 7054-7059
22. Sambrook, J., and Russell, D.W., (2001). "Molecular Cloningcloning: A a Laboratory laboratory Manualmanual." Third ed., 1. 3 vols. Cold Spring Harbor laboratory Press, Cold Spring Harbor, New York.
23. Schumacher D., Tischer B.K., Fuchs W., and Osterrieder N. Reconstitution of Marek's disease virus serotype 1 (MDV-1) from DNA cloned as a bacterial artificial chromosome and characterization of a glycoprotein B-negative MDV-1 mutant. J. Virol. 74 23 (2000) 11088-11098
24. Sun A.J., Petherbridge L.P., Zhao Y., Li Y.P., Nair V.K., and Cui Z.Z. A BAC clone of MDV strain GX0101 with REV-LTR integration retained its pathogenicity. Chinese Science Bulletin 54 15 (2009) 2641-2647
25. Sun S.H., Cui Z.Z., and Sun A.J. Comparisons of preventive effects of maternal antibody on immunosuppression induced by homologous and heterologous reticuloendotheliosis viruses. Acta Veterinaria et Zootechnica Sinica 38 5 (2007) 488-492
26. Tulman E.R., Afonso C.L., Lu Z., Zsak L., Rock D.L., and Kutish G.F. The genome of a very virulent Marek's disease virus. J. Virol. 74 17 (2000) 7980-7988
27. Witter R.L., Li D., Jones D., Lee L.F., and Kung H.J. Retroviral insertional mutagenesis of a herpesvirus: a Marek's disease virus mutant attenuated for oncogenicity but not for immunosuppression or in vivo replication. Avian Dis. 41 2 (1997) 407-421
28. Zhang Z., and Cui Z. Isolation of recombinant field strains of Marek's disease virus integration with reticuloendotheliosis virus genome fragments. Sci. China C. Life Sci. 48 1 (2005) 81-88
29. Zhao Y., Petherbridge L., Smith L.P., Baigent S., and Nair V. Self-excision of the BAC sequences from the recombinant Marek's disease virus genome increases replication and pathogenicity. Virol. J. 5 (2008) 19