Retroviral insertional activation in a herpesvirus: Transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus clone

Journal of Virology

Volumn 70, Issue 4, 1996, Pages 2460-2467

  Jones, Dan ^a   Brunovskis, Peter ^a   Witter, Richard ^b   Kung, Hsing Jien ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVIAN LYMPHOMATOSIS HERPETOVIRUS; CHICKEN; CONTROLLED STUDY; GENE EXPRESSION; HERPES VIRUS; LONG TERMINAL REPEAT; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; THYMUS ATROPHY; TRANSACTIVATION; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHICKENS; CHROMOSOME MAPPING; CLONING, MOLECULAR; GENES, VIRAL; HERPESVIRUS 2, GALLID; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; REPETITIVE SEQUENCES, NUCLEIC ACID; RETICULOENDOTHELIOSIS VIRUSES, AVIAN; VIRUS ACTIVATION; VIRUS INTEGRATION;

EID: 0029871775     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.4.2460-2467.1996     Document Type: Article

References (50)

1. Briskin, M. J., R. Y. Hsu, T. Boggs, J. A. Schultz, W. Rishell, and R. A. Bosselman. 1991. Heritable retroviral transgenes are highly expressed in chickens. Proc. Natl. Acad. Sci. USA 88:1736-1740.
2. Brunovskis, P. 1992. Ph.D. thesis. Michigan State University, E Lansing.
3. 2a.Brunovskis, P., and H.-J. Kung. Unpublished data.
4. 2b.Brunovskis, P., and L. F. Velicer. 1995. The Marek's disease virus unique short region: alphaherpesvirus-homologous, fowlpox virus-homologous, and MDV-specific genes. Virology 206:324-338.
5. Calnek, B. W., J. C. Carlisle, J. Fabricant, K. K. Murthy, and K. A. Schat. 1979. Comparative pathogenesis studies with oncogenic and nononcogenic Marek's disease viruses and turkey herpesvirus. Am. J. Vet Res 40:541-548
6. Chirgwin, J. M., A. E. Przbyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease Biochemistry 18:5295-5299.
7. Cui, Z. Z., L. F. Lee, E. J. Smith, R. L. Witter, and T. S. Chang. 1988. Monoclonal-antibody-mediated enzyme-linked immunosorbent assay for detection of reticuloendotheliosis viruses. Avian Dis. 32:32-40.
8. Frohman, M. A. 1990. RACE: rapid amplification of cDNA ends, p. 28-38. In M. A. Innis et al. (ed.), PCR protocols: a guide to methods and applications. Academic Press, San Diego, Calif.
9. Fukuchi, K., M. Sudo, Y.-S. Lee, A. Tanaka, and M. Nonoyama. 1984 Structure of Marek's disease virus DNA detailed restriction enzyme map. J. Virol. 51:102-109.
10. Fukuchi, K., A. Tanaka, L. W. Schierman, R. L. Witter, and M. Nonoyama. 1985. The structure of Marek's disease virus DNA: the presence of unique expansion in nonpathogenic viral DNA Proc. Natl. Acad. Sci. USA 82:751-754.
11. 8a.Hirai, K. Personal communication.
12. Hirano, A., and T. Wong. 1988. Functional interaction between transcriptional elements in the long terminal repeat of reticuloendothelioais virus cooperative DNA binding of promoter- and enhancer-specific factors. Mol Cell. Biol. 8:5232-5244
13. Holden, V. R., R. R. Yalamanchili, R. N. Harty, and D. J. O'Callaghan. 1992. Identification and characterization of an equine herpesvirus 1 late gene encoding a potential zinc finger. Virology 188:704-713.
14. Isfort, R., D. Jones, R. Kost, R. Witter, and H.-J. Kung. 1992 Retrovirus insertion into herpesvirus in vitro and in vivo. Proc Natl. Acad Sci. USA 89:991-995
15. Isfort, R., R. Witter, and H. J. Kung. 1994. Retrovirus insertion into herpesvirus Trends Microbiol 2:174-177.
16. Isfort, R. J., Z. Qian, D. Jones, R. F. Silva, R. Witter, and H. J. Kung. 1994 Integration of multiple chicken retroviruses into multiple chicken herpesviruses: herpesviral gD as a common target of integration. Virology. 203:125-133.
17. Isfort, R. J., R. L. Witter, and H. J. Kung. 1987. c-myc activation in an unusual retrovirus-induced avian T-lymphoma resembling Marek's disease proviral insertion of 5′ exon one enhances the expression of an intron promoter. Oncogene Res. 2:81-94.
18. Jones, D., R. Isfort, R. Witter, R. Kost, and H.-J. Kung. 1993 Retroviral insertions into a herpesvirus are clustered at the junctions of the short repeat and short unique sequences. Proc. Natl. Acad. Sci USA 90:3855-3859.
19. Kashanchi, F., J. Thompson, M. R. Sadaie, J. Doniger, J. Duvall, J. N. Brady, and L. J. Rosenthal. 1994. Transcriptional activation of minimal HIV-1 promoter by ORF-1 protein expressed from the Sall-L fragment of human herpesvirus 6. Virology 201:95-106.
20. Kost, R., D. Jones, R. Isfort, R. L. Witter, and H.-J. Kung. 1993 Retrovirus insertion into herpesvirus characterization of an attenuated Marck's disease virus harboring a solo LTR Virology 192:161-169
21. Kozak, M. 1992. A consideration of alternate models for the initiation of translation m eukaryotes. Crit. Rev. Biochem. Mol. Biol. 27:385-102
22. Kung, H.-J., C. Boerkoel, and T. H. Carter. 1991. Retroviral mutagenesis of cellular oncogenes. a review with insights into the mechanisms of insertional activation, p. 1-26. In H. J. Kung and P. K. Vogt (ed.), Retroviral insertion and oncogene activation Springer-Verlag, Berlin
23. Kung, H.-J., A. Tanaka, and M. Nonoyama. 1995. Two gene families of Marek's disease virus (MDV) with a potential role in tumor induction in chicken. Int. J. Oncol. 6:997-1002.
24. 20a.Li, D., and H.-J. Kung. Unpublished data.
25. 20b Li. D., and N. Ross. Personal communication.
26. Maotani, K., A. Kanamori, K. Ikuta, S. Ueda, S. Kato, and K. Hirai. 1986. Amplification of a tandem direct repeat within inverted repeats of Marek's disease virus DNA during serial in vitro passage. J. Virol. 58:657-660.
27. McGeoch, D. J., A. Dolan, S. Donald, and F. J. Rixon. 1985. Sequence determination and genetic content of the short unique region of the genome of herpes simplex virus type 1. J. Mol. Biol. 181:1-13.
28. McKnight, S. L., and R. Kingsbury. 1982 Transcription control signals of a eukaryotic protein-coding gene. Science 217:316-324.
29. Meignier, B. R., R. Longnecker, P. Maviomaia-Nazos, A. E. Sears, and B. Roizman. 1988. Virulence of and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1. Virology 162:251-254
30. Nicholas, J., and M. E. E. Martin. 1994. Nucleotide sequence analysis of a 39 5-kilobase-pair region of the genome of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene homologs and transactivating functions. J. Virol. 68:597-610.
31. Noori-Daloii, M. R., R. A. Swift, H.-J. Kung, and L. B. Crittenden. 1981. Specific integration of RHV proviruses in avian bursal lymphomas. Nature (London) 294:574-576.
32. Parcells, M. S., A. S. Anderson, J. L. Cantello, and R. W. Morgan. 1994. Characterization of Marek's disease virus infection and deletion mutants that lack US1 (ICP22 homolog), US10, and/or US2 and neighboring short-component open reading frames. J. Virol. 68:8239-8253.
33. Parcells, M. S., A. S. Anderson, and R. W. Morgan. 1995. Retention of oncogeincity by a Marek's disease virus mutant lacking six unique short region genes. J Virol. 69:7888-7898.
34. Rall, G. F., S. Kupershmidt, N. Sugg, R. A. Veach, and T. Ben-Porat. 1992. Functions of the sequences at the ends of the inverted repeats of pseudorabies virus. J. Virol. 66:1506-1519.
35. Reicin, A., J.-Q. Yang, K. B. Marcu, E. Fleissner, C. F. Koehne, and P. V. O'Donnell. 1986. Deregulation of the c-myc oncogene in virus-induced thymic lymphomas of AKR/J mice. Mol. Cell. Biol 6:4088-4092.
36. Ridgway, A. A. 1992 Reticuloendotheliosis virus long terminal repeat elements are efficient promoters in cells of various species and tissue origin, including human lymphoid cells. Gene 121:213-218.
37. Ridgway, A. A., R. A. Swift, H.-J. Kung, and D. J. Fujita. 1985 In vitro transcription analysis of the viral promoter involved in c-myc activation in chicken B lymphomas: detection and mapping of two RNA initiation sites within the reticuloendotheliosis virus long terminal repeat J. Virol. 54:161-170.
38. Sakaguchi, M., T. Urakawa, Y. Hirayama, N. Miki, M. Yamamoto, and K. Hirai. 1992. Sequence determination and genetic content of an 8.9-kb restriction fragment in the short unique region and the internal inverted repeat of Marek's disease virus type 1 DNA. Virus Genes 6:365-378.
39. Sanger, F., S. Nicklen, and A. R. Coulson. 1977 DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA 74:5463-5467.
40. Schat, K. A., B. W. Calnek, J. Fabricant, and D. L. Graham. 1985. Pathogenesis of infection with attenuated Marek's disease virus strains. Avian Pathol. 14:127-146.
41. Silva, R. F., and R. L. Witter. 1985. Genomic expansion of Marek's disease virus DNA is associated with serial in vitro passage. J. Virol. 54:690-696.
42. Stasiak, P. C., and E. S. Mocarski. 1992. Transactivation of the cytomegalovirus ICP36 gene promoter requires the a gene product TRS1 in addition to IE1 and IE2. J. Virol. 66:1050-1058.
43. Swift, R. A., C. Boerkoel, A. Ridgway, D. J. Fujita, J. B. Dodgson, and H.-J. Kung. 1987. B-lymphoma induction by reticuloendotheliosis virus: characterization of a mutated chicken syncytial virus provirus involved in c-myc activation. J. Virol. 61:2084-2090
44. Thomas, P. S. 1980. Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 77:5201.
45. Tomley, F., M. Binns, J. Campbell, and M. Boursnell. 1988. Sequence analysis of an 11 2 kilobase, near-terminal, BamHI fragment of fowlpox virus. J. Gen. Virol. 69:1025-1040.
46. Tsichlis, P. N., and P. A. Lazo. 1991. Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses, p. 95-171. In H. J. Kung and P. K Vogt (ed.), Retroviral insertion and oncogene activation. Springer-Verlag, Berlin.
47. Umene, K. 1987. Transition from a heterozygous to a homozygous state of a pair of loci in the inverted repeat sequences of the L component of the herpes simplex virus type 1 genome. J. Virol. 61:1187-1192.
48. Varmuzza, S. L., and J. R. Smiley, 1984. Unstable heterozygosity in a diploid region of herpes simplex DNA. J. Virol. 49:356-362.
49. Witter, R. L., and L. Offenbacker. 1979. Nonprotective and temperature-sensitive variants of Marek's disease vaccine viruses. J. Natl. Cancer Inst. 62:143-151.
50. Witter, R. L., and D. W. Solter. 1989. Vertical transmission of reticuloendotheliosis virus in breeder turkeys. Avian Dis. 33:226-235.