Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor

Virology

Volumn 397, Issue 2, 2010, Pages 369-378

  Choi, Young Bong ^a   Nicholas, John ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Angiogenesis; C EBP ; CCL2; HHV 8; MCP 1; ORF74; Transcription; vGPCR

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CHEMOKINE RECEPTOR CCR; G PROTEIN COUPLED RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG; VIRAL G PROTEIN COUPLED RECEPTOR;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN HERPESVIRUS 8; KAPOSI SARCOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS MUTATION; VIRUS PATHOGENESIS; VIRUS TRANSCRIPTION;

CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; CHEMOKINE CCL2; ENDOTHELIAL CELLS; HERPESVIRUS 8, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; RECEPTORS, CHEMOKINE;

HUMAN HERPESVIRUS 8;

EID: 75749145758     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.11.024     Document Type: Article

References (42)

1. Ablashi D.V., Chatlynne L.G., Whitman Jr. J.E., and Cesarman E. Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases. Clin. Microbiol. Rev. 15 3 (2002) 439-464
2. Abraham S., Sweet T., Sawaya B.E., Rappaport J., Khalili K., and Amini S. Cooperative interaction of C/EBP beta and Tat modulates MCP-1 gene transcription in astrocytes. J. Neuroimmunol. 160 1-2 (2005) 219-227
3. Aoki Y., Jaffe E.S., Chang Y., Jones K., Teruya-Feldstein J., Moore P.S., and Tosato G. Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6. Blood 93 12 (1999) 4034-4043
4. Bais C., Santomasso B., Coso O., Arvanitakis L., Raaka E.G., Gutkind J.S., Asch A.S., Cesarman E., Gershengorn M.C., and Mesri E.A. G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 391 6662 (1998) 86-89
5. Brinkmann M.M., Pietrek M., Dittrich-Breiholz O., Kracht M., and Schulz T.F. Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. J. Virol. 81 1 (2007) 42-58
6. Caselli E., Fiorentini S., Amici C., Di Luca D., Caruso A., and Santoro M.G. Human herpesvirus 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1-dependent capillary-like structure formation: role of the IKK/NF-kappaB pathway. Blood 109 7 (2007) 2718-2726
7. Chang Y., Cesarman E., Pessin M.S., Lee F., Culpepper J., Knowles D.M., and Moore P.S. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266 5192 (1994) 1865-1869
8. Chiou C.J., Poole L.J., Kim P.S., Ciufo D.M., Cannon J.S., ap Rhys C.M., Alcendor D.J., Zong J.C., Ambinder R.F., and Hayward G.S. Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus. J. Virol. 76 7 (2002) 3421-3439
9. Choi Y.B., and Nicholas J. Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines. J. Virol. 82 13 (2008) 6501-6513
10. Ensoli B., Sturzl M., and Monini P. Reactivation and role of HHV-8 in Kaposi's sarcoma initiation. Adv. Cancer Res. 81 (2001) 161-200
11. Fielding C.A., McLoughlin R.M., Colmont C.S., Kovaleva M., Harris D.A., Rose-John S., Topley N., and Jones S.A. Viral IL-6 blocks neutrophil infiltration during acute inflammation. J. Immunol. 175 6 (2005) 4024-4029
12. Glaunsinger B., and Ganem D. Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesis. J. Exp. Med. 200 3 (2004) 391-398
13. Glaunsinger B., and Ganem D. Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover. Mol. Cell. 13 5 (2004) 713-723
14. Hengge U.R., Ruzicka T., Tyring S.K., Stuschke M., Roggendorf M., Schwartz R.A., and Seeber S. Update on Kaposi's sarcoma and other HHV8 associated diseases: Part 2. Pathogenesis, Castleman's disease, and pleural effusion lymphoma. Lancet, Infect. Dis. 2 6 (2002) 344-352
15. Hu J., Roy S.K., Shapiro P.S., Rodig S.R., Reddy S.P., Platanias L.C., Schreiber R.D., and Kalvakolanu D.V. ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma. J. Biol. Chem. 276 1 (2001) 287-297
16. Hungness E.S., Pritts T.A., Luo G.J., Hershko D.D., Robb B.W., and Hasselgren P.O. IL-1beta activates C/EBP-beta and delta in human enterocytes through a mitogen-activated protein kinase signaling pathway. Int. J. Biochem. Cell Biol. 34 4 (2002) 382-395
17. Jensen K.K., and Lira S.A. Chemokines and Kaposi's sarcoma. Semin. Cancer Biol. 14 3 (2004) 187-194
18. Jeong J., Papin J., and Dittmer D. Differential regulation of the overlapping Kaposi's sarcoma-associated herpesvirus vGCR (orf74) and LANA (orf73) promoters. J. Virol. 75 4 (2001) 1798-1807
19. Kirshner J.R., Staskus K., Haase A., Lagunoff M., and Ganem D. Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis. J. Virol. 73 7 (1999) 6006-6014
20. Lee B.S., Lee S.H., Feng P., Chang H., Cho N.H., and Jung J.U. Characterization of the Kaposi's sarcoma-associated herpesvirus K1 signalosome. J. Virol. 79 19 (2005) 12173-12184
21. Martin D., Galisteo R., Ji Y., Montaner S., and Gutkind J.S. An NF-kappaB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia. Oncogene 27 13 (2008) 1844-1852
22. Montaner S., Sodhi A., Molinolo A., Bugge T.H., Sawai E.T., He Y., Li Y., Ray P.E., and Gutkind J.S. Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell. 3 1 (2003) 23-36
23. Mukerjee R., Deshmane S.L., Darbinian N., Czernik M., Khalili K., Amini S., and Sawaya B.E. St. John's Wort protein, p27SJ, regulates the MCP-1 promoter. Mol. Immunol. 45 15 (2008) 4028-4035
24. Nador R.G., Milligan L.L., Flore O., Wang X., Arvanitakis L., Knowles D.M., and Cesarman E. Expression of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor monocistronic and bicistronic transcripts in primary effusion lymphomas. Virology 287 1 (2001) 62-70
25. Nelson J.D., Denisenko O., and Bomsztyk K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat. Protoc. 1 1 (2006) 179-185
26. Pati S., Cavrois M., Guo H.G., Foulke Jr. J.S., Kim J., Feldman R.A., and Reitz M. Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis. J. Virol. 75 18 (2001) 8660-8673
27. Prakash O., Swamy O.R., Peng X., Tang Z.Y., Li L., Larson J.E., Cohen J.C., Gill J., Farr G., Wang S., and Samaniego F. Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis. Blood 105 10 (2005) 3987-3994
28. Sadagopan S., Sharma-Walia N., Veettil M.V., Raghu H., Sivakumar R., Bottero V., and Chandran B. Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression. J. Virol. 81 8 (2007) 3949-3968
29. Salcedo R., Ponce M.L., Young H.A., Wasserman K., Ward J.M., Kleinman H.K., Oppenheim J.J., and Murphy W.J. Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 96 1 (2000) 34-40
30. Samaniego F., Pati S., Karp J.E., Prakash O., and Bose D. Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation?. J. Natl. Cancer Inst. Monographs 28 (2001) 15-23
31. Schwarz M., and Murphy P.M. Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-kappa B and induces proinflammatory cytokine and chemokine production via a C-terminal signaling determinant. J. Immunol. 167 1 (2001) 505-513
32. Sciacca F.L., Sturzl M., Bussolino F., Sironi M., Brandstetter H., Zietz C., Zhou D., Matteucci C., Peri G., Sozzani S., et al. Expression of adhesion molecules, platelet-activating factor, and chemokines by Kaposi's sarcoma cells. J. Immunol. 153 10 (1994) 4816-4825
33. Sharma-Walia N., Krishnan H.H., Naranatt P.P., Zeng L., Smith M.S., and Chandran B. ERK1/2 and MEK1/2 induced by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) early during infection of target cells are essential for expression of viral genes and for establishment of infection. J. Virol. 79 16 (2005) 10308-10329
34. Stamatovic S.M., Keep R.F., Mostarica-Stojkovic M., and Andjelkovic A.V. CCL2 regulates angiogenesis via activation of Ets-1 transcription factor. J. Immunol. 177 4 (2006) 2651-2661
35. Tanimoto A., Murata Y., Wang K.Y., Tsutsui M., Kohno K., and Sasaguri Y. Monocyte chemoattractant protein-1 expression is enhanced by granulocyte-macrophage colony-stimulating factor via Jak2-Stat5 signaling and inhibited by atorvastatin in human monocytic U937 cells. J. Biol. Chem. 283 8 (2008) 4643-4651
36. Uccini S., Scarpino S., Ballarini F., Soriani A., Chilosi M., Montesu M.A., Masala M.V., Cottoni F., and Ruco L. In situ study of chemokine and chemokine-receptor expression in Kaposi sarcoma. Am. J. Dermatopathol. 25 5 (2003) 377-383
37. Ueda A., Okuda K., Ohno S., Shirai A., Igarashi T., Matsunaga K., Fukushima J., Kawamoto S., Ishigatsubo Y., and Okubo T. NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J. Immunol. 153 5 (1994) 2052-2063
38. Vart R.J., Nikitenko L.L., Lagos D., Trotter M.W., Cannon M., Bourboulia D., Gratrix F., Takeuchi Y., and Boshoff C. Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells. Cancer Res. 67 9 (2007) 4042-4051
39. Venetsanakos E., Mirza A., Fanton C., Romanov S.R., Tlsty T., and McMahon M. Induction of tubulogenesis in telomerase-immortalized human microvascular endothelial cells by glioblastoma cells. Exp. Cell Res. 273 1 (2002) 21-33
40. Wang L., Wakisaka N., Tomlinson C.C., DeWire S.M., Krall S., Pagano J.S., and Damania B. The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors. Cancer Res. 64 8 (2004) 2774-2781
41. Wolter S., Doerrie A., Weber A., Schneider H., Hoffmann E., von der Ohe J., Bakiri L., Wagner E.F., Resch K., and Kracht M. c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol. Cell. Biol. 28 13 (2008) 4407-4423
42. Yang T.Y., Chen S.C., Leach M.W., Manfra D., Homey B., Wiekowski M., Sullivan L., Jenh C.H., Narula S.K., Chensue S.W., and Lira S.A. Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma. J. Exp. Med. 191 3 (2000) 445-454