Activation of R235A mutant orotidine 5′-monophosphate decarboxylase by the guanidinium cation: Effective molarity of the cationic side chain of Arg-235

Biochemistry

Volumn 49, Issue 5, 2010, Pages 824-826

  Barnett, Shonoi A ^a   Amyes, Tina L ^a   Wood, B McKay ^b   Gerlt, John A ^b   Richard, John P ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DECARBOXYLASES; GUANIDINIUM CATIONS; MOLARITY; MONOPHOSPHATES; MUTANT ENZYMES; SIDE CHAINS; TRANSITION STATE; WILD-TYPE ENZYMES;

CARBOXYLATION; ENZYMES;

POSITIVE IONS;

ARGININE; GUANIDINE; MUTANT PROTEIN; OROTIDINE 5' PHOSPHATE DECARBOXYLASE;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DECARBOXYLATION; ENZYME ACTIVATION; ENZYME BINDING; ENZYME KINETICS; ENZYME STABILITY; IONIC STRENGTH; PRIORITY JOURNAL; WILD TYPE;

ALANINE; AMINO ACID SUBSTITUTION; ARGININE; CATALYSIS; CATIONS, MONOVALENT; ENZYME ACTIVATION; ENZYME STABILITY; FUNGAL PROTEINS; GUANIDINE; OROTIDINE-5'-PHOSPHATE DECARBOXYLASE; PROTEIN BINDING; PROTEIN SUBUNITS;

EID: 75749143420     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi902174q     Document Type: Article

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