Synthesis and antiviral activity of purine 2',3'-dideoxy-2',3'-difluoro-D- arabinofuranosyl nucleosides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 28, Issue 5-7, 2009, Pages 519-536

  Sivets, Grigorii G ^a   Kalinichenko, Elena N ^a   Mikhailopulo, Igor A ^a   Detorio, Mervi A ^b   McBrayer, Tami R ^b   Whitaker, Tony ^b   Schinazi, Raymond F ^b  

^a INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antiviral activity; Conformational analysis; Fluoro nucleosides; Purines

Indexed keywords

2 CHLORO 9 (2',3' DIDEOXY 2,3 DIFLUORO BETA DEXTRO ARABINOFURANOSYL)ADENINE; 9 (2',3' DIDEOXY 2',3' DIFLUORO BETA DEXTRO ARABINOFURANOSYL)ADENINE; ADENINE DERIVATIVE; NUCLEOSIDE DERIVATIVE; PURINE 2',3' DIDEOXY 2',3' DIFLUORO DEXTRO ARABINOFURANOSYL NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONFORMATION; DRUG SYNTHESIS; GLYCOSYLATION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERIZATION; REPLICON;

ANTIVIRAL AGENTS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; FLUORINE COMPOUNDS; HEPACIVIRUS; HEPATITIS C; HIV INFECTIONS; HIV-1; HUMANS; LYMPHOCYTES; MOLECULAR CONFORMATION; PURINE NUCLEOSIDES;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 75749124237     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770903053979     Document Type: Article

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