Inhibitory effects on bacterial growth and β-ketoacyl-ACP reductase by different species of maple leaf extracts and tannic acid

Phytotherapy Research

Volumn 24, Issue SUPPL. 1, 2010, Pages

  Wu, Dan ^a   Wu, Xiao Dong ^b   You, Xue Fu ^c   Ma, Xiao Feng ^a   Tian, Wei Xi ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

ketoacyl ACP reductase (FabG); Antibacteria; Enzyme inhibition; Maple leaves; Tannic acid

Indexed keywords

ACER CAMPESTRE EXTRACT; ACER PLATANOIDES EXTRACT; ACER RUBRUM EXTRACT; ACER TRUNCATUM EXTRACT; BETA KETOACYL ACP REDUCTASE; LEVOFLOXACIN; MAPLE LEAF EXTRACT; OXIDOREDUCTASE; PLANT EXTRACT; TANNIN; UNCLASSIFIED DRUG;

ACER; ACER CAMPESTRE; ACER PLATANOIDES; ACER RUBRUM; ACER SACCHARUM; ACER TRUNCATUM; ACINETOBACTER CALCOACETICUS; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CANADA; CHINA; CONTROLLED STUDY; DENMARK; ENTEROBACTER AEROGENES; ENTEROBACTER CLOACAE; ENTEROCOCCUS; ENZYME INHIBITION; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HIGHER PLANT; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLANT LEAF; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM; SERRATIA MARCESCENS; SHIGELLA DYSENTERIAE; SHIGELLA SONNEI; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

ACER; ALCOHOL OXIDOREDUCTASES; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL PROTEINS; FATTY ACIDS; MICROBIAL SENSITIVITY TESTS; OFLOXACIN; PLANT EXTRACTS; PLANT LEAVES; TANNINS;

ACER; ACER CAMPESTRE; ACER PLATANOIDES; ACER RUBRUM; ACER SACCHARUM; ACER TRUNCATUM; BACTERIA (MICROORGANISMS); NEGIBACTERIA; POSIBACTERIA;

EID: 75749123015     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2873     Document Type: Article

References (17)

1. Barbehenn R, Cheek S, Gasperut A, Lister E, Maben R. 2005. Phenolic compounds in red oak and sugar maple leaves have prooxidant activities in the midgut fluids of Malacosoma disstria and Orgyia leucostigma caterpillars. J Chem Ecol 31: 969-988.
2. Bhargava HN, Leonard PA. 1996. Triclosan: applications and safety. Am J Infect Control 24: 209-218.
3. Butler MS. 2004. The role of natural product chemistry in drug discovery. J Nat Prod 67: 2141-2153.
4. Cohen-Gonsaud M, Ducasse S, Hoh F, Zerbib D, Labesse G, Quemard A. 2002. Crystal structure of MabA from Mycobacterium tuberculosis, a reductase involved in long-chain fatty acid biosynthesis. J Mol Biol 320: 249-261.
5. Fisher M, Kroon JT, Martindale W, Stuitje AR, Slabas AR, Rafferty JB. 2000. The x-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis. Structure 8: 339-347.
6. Kumar A, Schweizer HP. 2005. Bacterial resistance to antibiotics: active efflux and reduced uptake. Adv Drug Deliv Rev 57: 1486-1513.
7. McMurry LM, Oethinger M, Levy SB. 1998. Triclosan targets lipid synthesis. Nature 394: 531-532.
8. Price AC, Zhang YM, Rock CO, White SW. 2001. Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis. Biochemistry 40: 12772-12781.
9. Ren Q, Sierro N, Witholt B, Kessler B. 2000. FabG, an NADPH-dependent 3-ketoacyl reductase of Pseudomonas aeruginosa, provides precursors for medium-chain-length poly-3-hydroxyalkanoate biosynthesis in Escherichia coli. J Bacteriol 182: 2978-2981.
10. Rock CO, Jackowski S. 2002. Forty years of bacterial fatty acid synthesis. Biochem Biophys Res Commun 292: 1155-1166.
11. Slayden RA, Lee RE, Barry CE 3rd. 2000. Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis. Mol Microbiol 38: 514-525.
12. Sun YH, Cheng Q, Tian WX, Wu XD. 2008. A substitutive substrate for measurements of beta-ketoacyl reductases in two fatty acid synthase systems. J Biochem Biophys Methods 70: 850-856.
13. Wang J, Kodali S, Lee SH et al. 2007. Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc Natl Acad Sci USA 104: 7612-7616.
14. Wang J, Soisson SM, Young K et al. 2006. Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441: 358-361.
15. Wright HT, Reynolds KA. 2007. Antibacterial targets in fatty acid biosynthesis. Curr Opin Microbiol 10: 447-453.
16. Zhang F, Luo SY, Ye YB et al. 2008. The antibacterial efficacy of aceraceous plant may be related to inhibition of bacterial beta-ketoacyl-ACP reductase (FabG). Biotechnol Appl Biochem 51: 73-78.
17. Zhang Y M, White SW, Rock CO. 2006. Inhibiting bacterial fatty acid synthesis. J Biol Chem 281: 17541-17544.