Isotopomics: A top-down systems biology approach for understanding dynamic metabolism in rats using [1,2-13C2] acetate

Analytical Chemistry

Volumn 82, Issue 2, 2010, Pages 646-653

  Godin, Jean Philippe ^a   Ross, Alastair B ^a   Rezzi, Serge ^a   Poussin, Carine ^a   Martin, Francois Pierre ^a   Fuerholz, Andreas ^a   Cléroux, Marilyn ^a   Mermoud, Anne France ^a   Tornier, Lionel ^a   Vera, Francia Arce ^a   Pouteau, Etienne ^a   Ramadan, Ziad ^a   Kochhar, Sunil ^a   Fay, Laurent Bernard ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

FREE FATTY ACID; GAS CHROMATOGRAPHY/MASS SPECTROMETRY; ISOTOPIC ENRICHMENT; KINETIC CURVES; MAMMALIAN SYSTEMS; MAPPING DYNAMICS; METABOLIC INTERMEDIATES; METABOLIC PATHWAYS; METABONOMICS; MOLE PERCENT; NOVEL APPLICATIONS; NUTRITIONAL STATE; PLASMA METABOLITES; PLASMA SAMPLES; QUANTITATIVE DATA; SHORT-CHAIN FATTY ACIDS; STABLE-ISOTOPE LABELING; SYSTEMS BIOLOGY; TIME DEPENDENT; TOPDOWN; TURNOVER RATE;

AMINO ACIDS; ANIMALS; BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; DYNAMIC RESPONSE; FATTY ACIDS; GLUCOSE; ISOTOPES; METABOLITES; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPEN SYSTEMS; ORGANIC ACIDS; RATS; RESONANCE; SODIUM;

METABOLISM;

ACETIC ACID; CARBON;

ANIMAL; ARTICLE; BLOOD; KINETICS; MALE; MASS FRAGMENTOGRAPHY; METABOLISM; METABOLOMICS; METHODOLOGY; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; TIME;

ANIMALS; CARBON ISOTOPES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOMICS; MULTIVARIATE ANALYSIS; RATS; SODIUM ACETATE; TIME FACTORS;

EID: 75649125313     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac902086g     Document Type: Article

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